LOCUS BC002974 1425 bp mRNA linear HUM 04-NOV-2003
DEFINITION Homo sapiens latrophilin 1, mRNA (cDNA clone IMAGE:3535311),
partial cds.
ACCESSION BC002974
VERSION BC002974.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1425)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1425)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (06-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: a Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22219461.
FEATURES Location/Qualifiers
source 1..1425
/db_xref="H-InvDB:HIT000086199"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3535311"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1425
/gene="LPHN1"
/gene_synonym="CIRL1"
/gene_synonym="FLJ11939"
/gene_synonym="KIAA0821"
/gene_synonym="LEC2"
/db_xref="GeneID:22859"
CDS <1..465
/gene="LPHN1"
/gene_synonym="CIRL1"
/gene_synonym="FLJ11939"
/gene_synonym="KIAA0821"
/gene_synonym="LEC2"
/codon_start=1
/product="LPHN1 protein"
/protein_id="AAH02974.1"
/db_xref="GeneID:22859"
/translation="VAGGPGGADRAEIELLYKALEEPLLLPRAQSVLYQSDLDESESC
TAEDGATSRPLSSPPGRDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEI
YYTSRPPALVARNPLQGYYQVRRPSHEGYLAAPGLEGPGPDGDGQMQLVTSL"
misc_feature 4..462
/gene="LPHN1"
/gene_synonym="CIRL1"
/gene_synonym="FLJ11939"
/gene_synonym="KIAA0821"
/gene_synonym="LEC2"
/note="Latrophilin; Region: Latrophilin Cytoplasmic
C-terminal region. This family consists of the cytoplasmic
C-terminal region in latrophilin. Latrophilin is a
synaptic Ca2+ independent alpha- latrotoxin (LTX) receptor
and is a novel member of the secretin family of G-protein
coupled receptors that are involved in secretion.
Latrophilin mRNA is present only in neuronal tissue.
Lactrophillin interacts with G-alpha O"
/db_xref="CDD:pfam02354"
BASE COUNT 272 a 461 c 441 g 251 t
ORIGIN
1 gtggcgggcg ggcccggggg tgctgaccgg gccgagattg aacttctcta taaggccctg
61 gaggagcctc tgctgctgcc ccgggcccag tcggtgctgt accagagcga tctggacgag
121 tcggagagct gcacggccga ggacggcgcc accagccggc ccctctcctc ccctcctggc
181 cgggactccc tctatgccag cggggccaac ctgcgggact caccctccta cccggacagc
241 agccctgagg ggcccagtga ggccctgccc ccaccccctc ccgcaccccc cggccccccc
301 gaaatctact acacctcgcg cccgccagcc ctggtggccc ggaatcccct gcagggctac
361 taccaggtgc ggcgtcctag ccacgagggc tacctggcag ccccaggcct tgaggggcca
421 gggcccgatg gggacgggca gatgcagctg gtcaccagtc tctgagggca cctcatggac
481 caggggctgg tggcccaggc cagggaggga accctgggca gggctctggt gggagaggga
541 gacagatgga ggcagtggct ggtgggccac tctctccagg tgcccctcag ccatgggccc
601 tacagtcccc tcaggggact ctaacctggg ggcctgaggt gccagggttc acagacaggg
661 tttcccacca gccacacgca ccagctctat ttgggggaag tgtagtgagg aggagcccag
721 aggaccccag gggagtgagg agggagaact tggaagggtg cagcccactt ccagactctc
781 ccctctccca cccttctacc ctgtgaaggg aaatgagggc tttagtttcc tgggcaggga
841 ggggcagctt ctgaggttgc caaaggcccc cactggatgg aacctgttag ctgctcctct
901 ccgcagccag aaatgctgcc ggctgcaccc agagggagca gtgaggcagg acagatggac
961 aggttcctcc tgcgctgtaa ttccctgctc cctggagact gggaaaaggc cgcagggcag
1021 ggggactggg cggtggtggc tggtggttta aaggttgaac tttctctgaa gctcctttcc
1081 ccttgctctt ggtccctgcc ccgcaagcaa acctgccccc tctgcctccc agtgcaccca
1141 atgaccccct cccttggggc gactcctgat gaagcacaac tccccgcagg gcccccagcc
1201 cacaggggtg gccatatttg ggcagttccc agtcctgtgg gctcggctat ctggggagca
1261 gattttgggt ctggatctcc ctggggagtg ggtcctgggc ttggatcttt ccctaggggg
1321 ccctcttact ccttcctctc tcctcctcct tccccattgc tgtaaatatt tcaacgaaat
1381 ggaaaagaaa aaaaaaagac aaaaaaaaaa aaaaaaaaaa aaaaa
//