LOCUS BC002851 984 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens proprotein convertase subtilisin/kexin type 1
inhibitor, mRNA (cDNA clone MGC:3466 IMAGE:3660001), complete cds.
ACCESSION BC002851
VERSION BC002851.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 984)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 984)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 31, 2003 this sequence version replaced BC002851.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: n Column: 24.
FEATURES Location/Qualifiers
source 1..984
/db_xref="H-InvDB:HIT000031239"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3466 IMAGE:3660001"
/tissue_type="Uterus, endometrium adenocarcinoma"
/clone_lib="NIH_MGC_44"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..984
/gene="PCSK1N"
/gene_synonym="PROSAAS"
/gene_synonym="SAAS"
/db_xref="GeneID:27344"
/db_xref="HGNC:HGNC:17301"
/db_xref="MIM:300399"
CDS 21..803
/gene="PCSK1N"
/gene_synonym="PROSAAS"
/gene_synonym="SAAS"
/codon_start=1
/product="proprotein convertase subtilisin/kexin type 1
inhibitor"
/protein_id="AAH02851.1"
/db_xref="GeneID:27344"
/db_xref="HGNC:HGNC:17301"
/db_xref="MIM:300399"
/translation="MAGSPLLWGPRAGGVGLLVLLLLGLFRPPPALCARPVKEPRGLS
AASPPLAETGAPRRFRRSVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQ
ARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARALLRARLDPAALAAQLVPAPVP
AAALRPRPPVYDDGPAGPDAEEAGDETPDVDPELLRYLLGRILAGSADSEGVAAPRRL
RRAADHDVGSELPPEGVLGALLRVKRLETPAPQVPARRLLPP"
BASE COUNT 134 a 379 c 338 g 133 t
ORIGIN
1 gcccggctcg ctggggcagc atggcggggt cgccgctgct ctgggggccg cgggccgggg
61 gcgtcggcct tttggtgctg ctgctgctcg gcctgtttcg gccgcccccc gcgctctgcg
121 cgcggccggt aaaggagccc cgcggcctaa gcgcagcgtc tccgcccttg gctgagactg
181 gcgctcctcg ccgcttccgg cggtcagtgc cccgaggtga ggcggcgggg gcggtgcagg
241 agctggcgcg ggcgctggcg catctgctgg aggccgaacg tcaggagcgg gcgcgggccg
301 aggcgcagga ggctgaggat cagcaggcgc gcgtcctggc gcagctgctg cgcgtctggg
361 gcgccccccg caactctgat ccggctctgg gcctggacga cgaccccgac gcgcctgcag
421 cgcagctcgc tcgcgctctg ctccgcgccc gccttgaccc tgccgcccta gcagcccagc
481 ttgtccccgc gcccgtcccc gccgcggcgc tccgaccccg gcccccggtc tacgacgacg
541 gccccgcggg cccggatgct gaggaggcag gcgacgagac acccgacgtg gaccccgagc
601 tgttgaggta cttgctggga cggattcttg cgggaagcgc ggactccgag ggggtggcag
661 ccccgcgccg cctccgccgt gccgccgacc acgatgtggg ctctgagctg ccccctgagg
721 gcgtgctggg ggcgctgctg cgtgtgaaac gcctagagac cccggcgccc caggtgcctg
781 cacgccgcct cttgccaccc tgagcactgc ccggatcccg tgcaccctgg gacccagaag
841 tgcccccgcc atcccgccac caggactgct ccccgccagc acgtccagag caacttaccc
901 cggccagcca gccctctcac ccgaggatcc ctaccccctg gccccacaat aaacatgatc
961 tgaagcaaaa aaaaaaaaaa aaaa
//