LOCUS BC002838 2004 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 8, mRNA (cDNA clone
MGC:3358 IMAGE:3635744), complete cds.
ACCESSION BC002838
VERSION BC002838.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2004)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2004)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC002838.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: l Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34147427.
FEATURES Location/Qualifiers
source 1..2004
/db_xref="H-InvDB:HIT000031229"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3358 IMAGE:3635744"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2004
/gene="PLEKHA8"
/gene_synonym="FAPP2"
/gene_synonym="MGC3358"
/db_xref="GeneID:84725"
/db_xref="HGNC:HGNC:30037"
/db_xref="MIM:608639"
CDS 92..1414
/gene="PLEKHA8"
/gene_synonym="FAPP2"
/gene_synonym="MGC3358"
/codon_start=1
/product="pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 8"
/protein_id="AAH02838.1"
/db_xref="GeneID:84725"
/db_xref="HGNC:HGNC:30037"
/db_xref="MIM:608639"
/translation="MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSI
QMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQK
EKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCN
TFLKTLEECMQIANAAFTSELLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELS
TCENGSLNMEINGEEEILMKNKNSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGM
ENLKNHDNNLTQSGSDSSCSPECLWEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEA
FLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEA
DVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALRNPTENT"
BASE COUNT 682 a 375 c 467 g 480 t
ORIGIN
1 aggcgatggc cctgctgctg gtgctcctcg cctcttgggg cctggggcag tgagggggcc
61 ggcgggcgtg ggccgagtgg ccgcgggcgc catggagggg gtgctgtaca agtggaccaa
121 ctatctgagc ggttggcagc ctcgatggtt ccttctctgt gggggaatat tgtcctatta
181 tgattctcct gaagatgcct ggaaaggttg caaagggagc atacaaatgg cagtctgtga
241 aattcaagtt cattctgtag ataatacacg catggacctg ataatccctg gggaacagta
301 tttctacctg aaggccagaa gtgtggctga aagacagcgg tggctggtgg ccctgggatc
361 agccaaggct tgcctgactg acagtaggac ccagaaggag aaagagtttg ctgaaaacac
421 tgaaaacttg aaaaccaaaa tgtcagaact aagactctac tgtgacctcc ttgttcagca
481 agtagataaa acaaaagaag tgaccacaac tggtgtgtcc aattctgagg agggaattga
541 tgtgggaact ttgctgaaat caacctgtaa tacttttctg aagaccttgg aagaatgcat
601 gcagatcgca aatgcagcct tcacctctga gctgctctac cgcactccac caggatcacc
661 tcagctggcc atgctcaagt ccagcaagat gaaacatcct attataccaa ttcataattc
721 attggaaagg caaatggagt tgagcacttg tgaaaatgga tctttaaata tggaaataaa
781 tggtgaggaa gaaatcctaa tgaaaaataa gaattcctta tatttgaaat ctgcagagat
841 agactgcagc atatcaagtg aggaaaatac agatgataat ataacagtcc aaggtgaaat
901 aaggaaggaa gatggaatgg aaaacctgaa aaatcatgac aataacttga ctcagtctgg
961 atcagactca agttgctctc cggaatgcct ctgggaggaa ggcaaagaag ttatcccaac
1021 tttctttagt accatgaaca caagctttag tgacattgaa cttctggaag acagtggcat
1081 tcccacagaa gcattcttgg catcatgtta tgctgtggtt ccagtattag acaaacttgg
1141 ccctacagtg tttgctcctg ttaagatgga tcttgttgga aatattaaga aagtaaatca
1201 gaagtatata accaacaaag aagagtttac cactctccag aagatagtgc tgcacgaagt
1261 ggaggcggat gtagcccagg ttaggaactc agcgactgaa gccctcttgt ggctgaagag
1321 aggtctcaaa tttttgaagg gatttttgac agaagtgaaa aatggggaga aggatatcca
1381 gacagcccta agaaatccaa cagaaaacac ttgacaccaa aacataccct gatgaagatc
1441 ctgaacttca agaatgaaga aagaattcct caccattcag gcagaaaaag caagtcacca
1501 agggacctca aacttccttt ccacaagatt ctgtgacggg aaacaatggg ggagtatttc
1561 cgaagttctg agtaggaaaa aagaatgact caaatgtatt attgccaacc aagtcgtcaa
1621 atctaatgtc aagttctctt aagcaggtaa gaactcagaa cataatacct gagtgccttc
1681 ttaaggaaac catttgatag gaaagatgaa ccaaataact caatgatgga tgagctggta
1741 gaaaaaaagc tggtggtgaa ccaaggtcaa actggaaatt atagtcacag tatagatata
1801 gattataaat attacaaacc ctaagatagc taataaattg ggaatgggag aagggaggat
1861 ataagagcac taatgccctc ttattttcat agcagagact tgatactgtc tcaacttttt
1921 tcaaaaacac aatttcttaa attttttggt aatcttttaa ataaacagat ttctaaaaag
1981 aaaaaaaaaa aaaaaaaaaa aaaa
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