LOCUS BC002824 2137 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens SRY (sex determining region Y)-box 10, mRNA (cDNA
clone MGC:3510 IMAGE:3635492), complete cds.
ACCESSION BC002824
VERSION BC002824.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2137)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2137)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC002824.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: h Column: 8.
FEATURES Location/Qualifiers
source 1..2137
/db_xref="H-InvDB:HIT000031216"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3510 IMAGE:3635492"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2137
/gene="SOX10"
/gene_synonym="DOM"
/gene_synonym="MGC15649"
/gene_synonym="WS4"
/db_xref="GeneID:6663"
/db_xref="HGNC:HGNC:11190"
/db_xref="MIM:602229"
CDS 93..1493
/gene="SOX10"
/gene_synonym="DOM"
/gene_synonym="MGC15649"
/gene_synonym="WS4"
/codon_start=1
/product="SRY (sex determining region Y)-box 10"
/protein_id="AAH02824.1"
/db_xref="GeneID:6663"
/db_xref="HGNC:HGNC:11190"
/db_xref="MIM:602229"
/translation="MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGGGSGLRA
SPGPGELGKVKKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKP
HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERL
RMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPG
EGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGNV
DIGEISHEVMSNMETFDVAELDQYLPPNGHPGHVSSYSAAGYGLGSALAVASGHSAWI
SKPPGVALPTVSPPGVDAKAQVKTETAGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAF
PSISRPQFDYSDHQPSGPYYGHSGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSH
SPTHWEQPVYTTLSRP"
BASE COUNT 428 a 724 c 678 g 307 t
ORIGIN
1 ccgaggaggt gggcgttgga ctctttgcga ggaccccggc ggctggcccg ggggaggcgg
61 ccgaggcggc ggcggcggcg gccgggggcg acatggcgga ggagcaggac ctatcggagg
121 tggagctgag ccccgtgggc tcggaggagc cccgctgcct gtccccgggg agcgcgccct
181 cgctagggcc cgacggcggc ggcggcggat cgggcctgcg agccagcccg gggccaggcg
241 agctgggcaa ggtcaagaag gagcagcagg acggcgaggc ggacgatgac aagttccccg
301 tgtgcatccg cgaggccgtc agccaggtgc tcagcggcta cgactggacg ctggtgccca
361 tgcccgtgcg cgtcaacggc gccagcaaaa gcaagccgca cgtcaagcgg cccatgaacg
421 ccttcatggt gtgggctcag gcagcgcgca ggaagctcgc ggaccagtac ccgcacctgc
481 acaacgctga gctcagcaag acgctgggca agctctggag gctgctgaac gaaagtgaca
541 agcgcccctt catcgaggag gctgagcggc tccgtatgca gcacaagaaa gaccacccgg
601 actacaagta ccagcccagg cggcggaaga acgggaaggc cgcccagggc gaggcggagt
661 gccccggtgg ggaggccgag caaggtggga ccgccgccat ccaggcccac tacaagagcg
721 cccacttgga ccaccggcac ccaggagagg gctcccccat gtcagatggg aaccccgagc
781 acccctcagg ccagagccat ggcccaccca cccctccaac caccccgaag acagagctgc
841 agtcgggcaa ggcagacccg aagcgggacg ggcgctccat gggggagggc gggaagcctc
901 acatcgactt cggcaacgtg gacattggtg agatcagcca cgaggtaatg tccaacatgg
961 agacctttga tgtggctgag ttggaccagt acctgccgcc caatgggcac ccaggccatg
1021 tgagcagcta ctcagcagcc ggctatgggc tgggcagtgc cctggccgtg gccagtggac
1081 actccgcctg gatctccaag ccaccaggcg tggctctgcc cacggtctca ccacctggtg
1141 tggatgccaa agcccaggtg aagacagaga ccgcggggcc ccaggggccc ccacactaca
1201 ccgaccagcc atccacctca cagatcgcct acacctccct cagcctgccc cactatggct
1261 cagccttccc ctccatctcc cgcccccagt ttgactactc tgaccatcag ccctcaggac
1321 cctattatgg ccactcgggc caggcctctg gcctctactc ggccttctcc tatatggggc
1381 cctcgcagcg gcccctctac acggccatct ctgaccccag cccctcaggg ccccagtccc
1441 acagccccac acactgggag cagccagtat atacgacact gtcccggccc taaagggggc
1501 cctgtcgcca ccaccccccg cccagcccct gcccccagcc tgtgtgccct gttccttgcc
1561 cacctcaggc ctggtggtgg cagtggagga ggctgaggag gctgaagagg ctgacaggtc
1621 ggggggcttt ctgtctggct cactgccctg atgacccacc cgccccatcc aggctccagc
1681 agcaaagccc caggagaaca ggctggacag aggagaagga ggttgactgt tgcacccaca
1741 ctgaaagatg aggggctgca ccttccccca ggaatgaccc tctatcccag gacctgagaa
1801 gggcctgctc accctcctcg gggaggggaa gcaccagggt tggtggcatc ggaggcctta
1861 ccactcctat gactcctgtt ttctctctca cagatagtga gggtctgaca tgcccatgcc
1921 acctatgcca cagtgcctaa gggctaggcc acccagagac tgtgcccgga gctggccgtg
1981 tctcccactc aggggctgag agtagctttg aggagcctca ttggggagtg gggggttcga
2041 gggacttagt ggagttctca tcccttcaat gccccctccc tttctgaagg caggaaggag
2101 ttggcacaga ggccccctga aaaaaaaaaa aaaaaaa
//