LOCUS BC002795 2409 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens plasminogen activator, tissue, mRNA (cDNA clone
MGC:3677 IMAGE:3618149), complete cds.
ACCESSION BC002795
VERSION BC002795.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2409)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2409)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002795.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: p Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14702165.
FEATURES Location/Qualifiers
source 1..2409
/db_xref="H-InvDB:HIT000031190"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3677 IMAGE:3618149"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2409
/gene="PLAT"
/gene_synonym="T-PA"
/gene_synonym="TPA"
/db_xref="GeneID:5327"
/db_xref="HGNC:HGNC:9051"
/db_xref="MIM:173370"
CDS 84..1634
/gene="PLAT"
/gene_synonym="T-PA"
/gene_synonym="TPA"
/codon_start=1
/product="plasminogen activator, tissue"
/protein_id="AAH02795.3"
/db_xref="GeneID:5327"
/db_xref="HGNC:HGNC:9051"
/db_xref="MIM:173370"
/translation="MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQGCSEPR
CFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAEC
TNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTP
ACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKH
NYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASH
PWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVP
GEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQL
PDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDT
RSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLD
WIRDNMRP"
BASE COUNT 594 a 654 c 646 g 515 t
ORIGIN
1 caggagtcca gggctggaga gaaaacctct gcgaggaaag ggaaggagca agccgtgaat
61 ttaagggacg ctgtgaagca atcatggatg caatgaagag agggctctgc tgtgtgctgc
121 tgctgtgtgg agcagtcttc gtttcgccca gccaggaaat ccatgcccga ttcagaagag
181 gagccagatc ttaccaaggt tgcagcgagc caaggtgttt caacgggggc acctgccagc
241 aggccctgta cttctcagat ttcgtgtgcc agtgccccga aggatttgct gggaagtgct
301 gtgaaataga taccagggcc acgtgctacg aggaccaggg catcagctac aggggcacgt
361 ggagcacagc ggagagtggc gccgagtgca ccaactggaa cagcagcgcg ttggcccaga
421 agccctacag cgggcggagg ccagacgcca tcaggctggg cctggggaac cacaactact
481 gcagaaaccc agatcgagac tcaaagccct ggtgctacgt ctttaaggcg gggaagtaca
541 gctcagagtt ctgcagcacc cctgcctgct ctgagggaaa cagtgactgc tactttggga
601 atgggtcagc ctaccgtggc acgcacagcc tcaccgagtc gggtgcctcc tgcctcccgt
661 ggaattccat gatcctgata ggcaaggttt acacagcaca gaaccccagt gcccaggcac
721 tgggcctggg caaacataat tactgccgga atcctgatgg ggatgccaag ccctggtgcc
781 acgtgctgaa gaaccgcagg ctgacgtggg agtactgtga tgtgccctcc tgctccacct
841 gcggcctgag acagtacagc cagcctcagt ttcgcatcaa aggagggctc ttcgccgaca
901 tcgcctccca cccctggcag gctgccatct ttgccaagca caggaggtcg cccggagagc
961 ggttcctgtg cgggggcata ctcatcagct cctgctggat tctctctgcc gcccactgct
1021 tccaggagag gtttccgccc caccacctga cggtgatctt gggcagaaca taccgggtgg
1081 tccctggcga ggaggagcag aaatttgaag tcgaaaaata cattgtccat aaggaattcg
1141 atgatgacac ttacgacaat gacattgcgc tgctgcagct gaaatcggat tcgtcccgct
1201 gtgcccagga gagcagcgtg gtccgcactg tgtgccttcc cccggcggac ctgcagctgc
1261 cggactggac ggagtgtgag ctctccggct acggcaagca tgaggccttg tctcctttct
1321 attcggagcg gctgaaggag gctcatgtca gactgtaccc atccagccgc tgcacatcac
1381 aacatttact taacagaaca gtcaccgaca acatgctgtg tgctggagac actcggagcg
1441 gcgggcccca ggcaaacttg cacgacgcct gccagggcga ttcgggaggc cccctggtgt
1501 gtctgaacga tggccgcatg actttggtgg gcatcatcag ctggggcctg ggctgtggac
1561 agaaggatgt cccgggtgtg tacaccaagg ttaccaacta cctagactgg attcgtgaca
1621 acatgcgacc gtgaccagga acacccgact cctcaaaagc aaatgagatc ccgcctcttc
1681 ttcttcagaa gacactgcaa aggcgcagtg cttctctaca gacttctcca gacccaccac
1741 accgcagaag cgggacgaga ccctacagga gagggaagag tgcattttcc cagatacttc
1801 ccattttgga agttttcagg acttggtctg atttcaggat actctgtcag atgggaagac
1861 atgaatgcac actagcctct ccaggaatgc ctcctccctg ggcagaaagt ggccatgcca
1921 ccctgttttc agctaaagcc caacctcctg acctgtcacc gtgagcagct ttggaaacag
1981 gaccacaaaa atgaaagcat gtctcaatag taaaagataa caagatcttt caggaaagac
2041 ggattgcatt agaaatagac agtatattta tagtcacaag agcccagcag ggcctcaaag
2101 ttggggcagg ctggctggcc cgtcatgttc ctcaaaagca cccttgacgt caagtctcct
2161 tcccctttcc ccactccctg gctctcagaa ggtattcctt ttgtgtacag tgtgtaaagt
2221 gtaaatcctt tttctttata aactttagag tagcatgaga gaattgtatc atttgaacaa
2281 ctaggcttca gcatatttat agcaatccat gttagttttt actttctgtt gccacaaccc
2341 tgttttatac tgtacttaat aaattcagat atatttttca cagtttttcc aaaaaaaaaa
2401 aaaaaaaaa
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