LOCUS BC002704 2629 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens signal transducer and activator of transcription 1,
91kDa, mRNA (cDNA clone MGC:3493 IMAGE:3627218), complete cds.
ACCESSION BC002704
VERSION BC002704.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2629)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2629)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002704.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: a Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21536299.
FEATURES Location/Qualifiers
source 1..2629
/db_xref="H-InvDB:HIT000031113"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3493 IMAGE:3627218"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2629
/gene="STAT1"
/gene_synonym="ISGF-3"
/gene_synonym="STAT91"
/db_xref="GeneID:6772"
/db_xref="HGNC:HGNC:11362"
/db_xref="MIM:600555"
CDS 307..2445
/gene="STAT1"
/gene_synonym="ISGF-3"
/gene_synonym="STAT91"
/codon_start=1
/product="signal transducer and activator of transcription
1, 91kDa"
/protein_id="AAH02704.1"
/db_xref="GeneID:6772"
/db_xref="HGNC:HGNC:11362"
/db_xref="MIM:600555"
/translation="MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWE
HAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMS
MIIYSCLKEERKILENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEI
KSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKII
ELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQ
LKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLV
LKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNM
EESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPGLVIDLET
TSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSS
VTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKENINDKNFPFWLWIESILELIK
KHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGG
EPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYS
RPKEAPEPMELDGPKGTGYIKTELISVSEV"
BASE COUNT 746 a 594 c 653 g 636 t
ORIGIN
1 tcgctttcct gcgcagagtc tgcggagggg ctcggctgca ccggggggat cgcgcctggc
61 agaccccaga ccgagcagag gcgacccagc gcgctcggga gaggctgcac cgccgcgccc
121 ccgcctagcc cttccggatc ctgcgcgcag aaaagtttca tttgctgtat gccatcctcg
181 agagctgtct aggttaacgt tcgcactctg tgtatataac ctcgacagtc ttggcaccta
241 acgtgctgtg cgtagctgct cctttggttg aatccccagg cccttgttgg ggcacaaggt
301 ggcaggatgt ctcagtggta cgaacttcag cagcttgact caaaattcct ggagcaggtt
361 caccagcttt atgatgacag ttttcccatg gaaatcagac agtacctggc acagtggtta
421 gaaaagcaag actgggagca cgctgccaat gatgtttcat ttgccaccat ccgttttcat
481 gacctcctgt cacagctgga tgatcaatat agtcgctttt ctttggagaa taacttcttg
541 ctacagcata acataaggaa aagcaagcgt aatcttcagg ataattttca ggaagaccca
601 atccagatgt ctatgatcat ttacagctgt ctgaaggaag aaaggaaaat tctggaaaac
661 gcccagagat ttaatcaggc tcagtcgggg aatattcaga gcacagtgat gttagacaaa
721 cagaaagagc ttgacagtaa agtcagaaat gtgaaggaca aggttatgtg tatagagcat
781 gaaatcaaga gcctggaaga tttacaagat gaatatgact tcaaatgcaa aaccttgcag
841 aacagagaac acgagaccaa tggtgtggca aagagtgatc agaaacaaga acagctgtta
901 ctcaagaaga tgtatttaat gcttgacaat aagagaaagg aagtagttca caaaataata
961 gagttgctga atgtcactga acttacccag aatgccctga ttaatgatga actagtggag
1021 tggaagcgga gacagcagag cgcctgtatt ggggggccgc ccaatgcttg cttggatcag
1081 ctgcagaact ggttcactat agttgcggag agtctgcagc aagttcggca gcagcttaaa
1141 aagttggagg aattggaaca gaaatacacc tacgaacatg accctatcac aaaaaacaaa
1201 caagtgttat gggaccgcac cttcagtctt ttccagcagc tcattcagag ctcgtttgtg
1261 gtggaaagac agccctgcat gccaacgcac cctcagaggc cgctggtctt gaagacaggg
1321 gtccagttca ctgtgaagtt gagactgttg gtgaaattgc aagagctgaa ttataatttg
1381 aaagtcaaag tcttatttga taaagatgtg aatgagagaa atacagtaaa aggatttagg
1441 aagttcaaca ttttgggcac gcacacaaaa gtgatgaaca tggaggagtc caccaatggc
1501 agtctggcgg ctgaatttcg gcacctgcaa ttgaaagaac agaaaaatgc tggcaccaga
1561 acgaatgagg gtcctctcat cgttactgaa gagcttcact cccttagttt tgaaacccaa
1621 ttgtgccagc ctggtttggt aattgacctc gagacgacct ctctgcccgt tgtggtgatc
1681 tccaacgtca gccagctccc gagcggttgg gcctccatcc tttggtacaa catgctggtg
1741 gcggaaccca ggaatctgtc cttcttcctg actccaccat gtgcacgatg ggctcagctt
1801 tcagaagtgc tgagttggca gttttcttct gtcaccaaaa gaggtctcaa tgtggaccag
1861 ctgaacatgt tgggagagaa gcttcttggt cctaacgcca gccccgatgg tctcattccg
1921 tggacgaggt tttgtaagga aaatataaat gataaaaatt ttcccttctg gctttggatt
1981 gaaagcatcc tagaactcat taaaaaacac ctgctccctc tctggaatga tgggtgcatc
2041 atgggcttca tcagcaagga gcgagagcgt gccctgttga aggaccagca gccggggacc
2101 ttcctgctgc ggttcagtga gagctcccgg gaaggggcca tcacattcac atgggtggag
2161 cggtcccaga acggaggcga acctgacttc catgcggttg aaccctacac gaagaaagaa
2221 ctttctgctg ttactttccc tgacatcatt cgcaattaca aagtcatggc tgctgagaat
2281 attcctgaga atcccctgaa gtatctgtat ccaaatattg acaaagacca tgcctttgga
2341 aagtattact ccaggccaaa ggaagcacca gagccaatgg aacttgatgg ccctaaagga
2401 actggatata tcaagactga gttgatttct gtgtctgaag tgtaagtgaa cacagaagag
2461 tgacatgttt acaaacctca agccagcctt gctcctggct ggggcctgtt gaagatgctt
2521 gtattttact tttccattgt aattgctatc gccatcacag ctgaacttgt tgagatcccc
2581 gtgttactgc ctatcagcat tttactactt taaaaaaaaa aaaaaaaaa
//