LOCUS BC002671 1840 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens dual specificity phosphatase 4, mRNA (cDNA clone
MGC:3713 IMAGE:3605895), complete cds.
ACCESSION BC002671
VERSION BC002671.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1840)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1840)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002671.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: k Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 58331238.
FEATURES Location/Qualifiers
source 1..1840
/db_xref="H-InvDB:HIT000031083"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3713 IMAGE:3605895"
/tissue_type="Uterus, endometrium adenocarcinoma"
/clone_lib="NIH_MGC_44"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1840
/gene="DUSP4"
/gene_synonym="HVH2"
/gene_synonym="MKP-2"
/gene_synonym="MKP2"
/gene_synonym="TYP"
/db_xref="GeneID:1846"
/db_xref="HGNC:HGNC:3070"
/db_xref="MIM:602747"
CDS 159..1343
/gene="DUSP4"
/gene_synonym="HVH2"
/gene_synonym="MKP-2"
/gene_synonym="MKP2"
/gene_synonym="TYP"
/codon_start=1
/product="dual specificity phosphatase 4"
/protein_id="AAH02671.1"
/db_xref="GeneID:1846"
/db_xref="HGNC:HGNC:3070"
/db_xref="MIM:602747"
/translation="MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGK
CLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLY
SAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSK
TKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLD
ALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRV
LVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQV
LATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSP
SC"
BASE COUNT 374 a 574 c 541 g 351 t
ORIGIN
1 ggaagaagag gctctcccgc gggagccctt gaggaccaag tttgcggcca cttctgcagg
61 cgtcccttct tagctctcgc ccgccccttt ctgcagccta ggcggcccgg gttctcttct
121 cttcctcgcg cgcccagccg cctcggttcc cggcgaccat ggtgacgatg gaggagctgc
181 gggagatgga ctgcagtgtg ctcaaaaggc tgatgaaccg ggacgagaat ggcggcggcg
241 cgggcggcag cggcagccac ggcaccctgg ggctgccgag cggcggcaag tgcctgctgc
301 tggactgcag accgttcctg gcgcacagcg cgggctacat cctaggttcg gtcaacgtgc
361 gctgtaacac catcgtgcgg cggcgggcta agggctccgt gagcctggag cagatcctgc
421 ccgccgagga ggaggtacgc gcccgcttgc gctccggcct ctactcggcg gtcatcgtct
481 acgacgagcg cagcccgcgc gccgagagcc tccgcgagga cagcaccgtg tcgctggtgg
541 tgcaggcgct gcgccgcaac gccgagcgca ccgacatctg cctgctcaaa ggcggctatg
601 agaggttttc ctccgagtac ccagaattct gttctaaaac caaggccctg gcagccatcc
661 cacccccggt tccccccagc gccacagagc ccttggacct gggctgcagc tcctgtggga
721 ccccactaca cgaccagggg ggtcctgtgg agatccttcc cttcctctac ctcggcagtg
781 cctaccatgc tgcccggaga gacatgctgg acgccctggg catcacggct ctgttgaatg
841 tctcctcgga ctgcccaaac cactttgaag gacactatca gtacaagtgc atcccagtgg
901 aagataacca caaggccgac atcagctcct ggttcatgga agccatagag tacatcgatg
961 ccgtgaagga ctgccgtggg cgcgtgctgg tgcactgcca ggcgggcatc tcgcggtcgg
1021 ccaccatctg cctggcctac ctgatgatga agaaacgggt gaggctggag gaggccttcg
1081 agttcgttaa gcagcgccgc agcatcatct cgcccaactt cagcttcatg gggcagctgc
1141 tgcagttcga gtcccaggtg ctggccacgt cctgtgctgc ggaggctgct agcccctcgg
1201 gacccctgcg ggagcggggc aagacccccg ccacccccac ctcgcagttc gtcttcagct
1261 ttccggtctc cgtgggcgtg cactcggccc ccagcagcct gccctacctg cacagcccca
1321 tcaccacctc tcccagctgt tagagccgcc ctgggggccc cagaaccaga gctggctccc
1381 agcaagggta ggacgggccg catgcgggca gaaagttggg actgagcagc tgggagcagg
1441 cgaccgagct ccttccccat catttctcct tggccaacga cgaggccagc cagaatggca
1501 ataaggactc cgaatacata ataaaagcaa acagaacact ccaacttaga gcaataacgg
1561 ctgccgcagc agccagggaa gaccttggtt tggtttatgt gtcagtttca cttttccgat
1621 agaaatttct tacctcattt ttttaagcag taaggcttga agtgatgaaa cccacagatc
1681 ctagcaaatg tgcccaacca gctttactaa agggggagga agggagggca aagggatgag
1741 aagacaagtt tcccagaagt gcctggttct gtgtacttgt ccctttgttg tcgttgttgt
1801 agttaaagga atttcatttt ttaaaaaaaa aaaaaaaaaa
//