LOCUS BC002630 2068 bp mRNA linear HUM 04-NOV-2003
DEFINITION Homo sapiens integrin, beta 8, mRNA (cDNA clone MGC:3946
IMAGE:3609490), complete cds.
ACCESSION BC002630
VERSION BC002630.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2068)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2068)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 31, 2003 this sequence version replaced BC002630.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 12 Row: a Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504778.
FEATURES Location/Qualifiers
source 1..2068
/db_xref="H-InvDB:HIT000031048"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3946 IMAGE:3609490"
/tissue_type="Uterus, endometrium adenocarcinoma"
/clone_lib="NIH_MGC_44"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2068
/gene="ITGB8"
/db_xref="GeneID:3696"
/db_xref="MIM:604160"
CDS 706..2025
/gene="ITGB8"
/codon_start=1
/product="ITGB8 protein"
/protein_id="AAH02630.1"
/db_xref="GeneID:3696"
/db_xref="MIM:604160"
/translation="MCGSALAFFTAAFVCLQNDRRGPASFLWAAWVFSLVLGLGQGED
NRCASSNAASCARCLALGPECGWCVQEDFISGGSRSERCDIVSNLISKGCSVDSIEYP
SVHVIIPTENEINTQVTPGEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMH
NNIEKLNSVGNDLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDC
MPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEA
KRLLLVMTDQTSHLALDSKLAGIVVPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLID
NNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAANLNNLVVEAYQKLISEVKVQV
ENQVQGIYFNITAICPDGSRKPGMEGCRNVTSNDEVCGCAFFPFKIN"
misc_feature 889..1989
/gene="ITGB8"
/note="integrin_B; Region: Integrin, beta chain. Sequences
cut off at repeats due to overlap with EGF"
/db_xref="CDD:pfam00362"
BASE COUNT 511 a 523 c 525 g 509 t
ORIGIN
1 ggcgggtgct tctagggcgc tcccagagcc gcctccccct gttgctggca tcccgagctt
61 cctcccttgc cagccaggac gctgccgact tgtctttgcc cgctgctccg cagacggggc
121 tgcaaagctg caactaatgg tgttggcctc cctgcccacc tgtggaagca actgcgctga
181 ttgatgcgcc acagactttt ttcccctcga cctcgccggc gtcccctccc acagatccag
241 catcacccag tgaatgtaca ttagggtggt ttccccccca gcttcgggct ttgtttgggt
301 ttgattgtgt ttggctcttc gctaagctga tttatgcagc agaagcccca ccggctggag
361 agaaacaaaa gctcttttct ttgtcccgga gcaggctgcg gagcccttgc agagccctct
421 ctccagtcgc cgccggggcc cttggccgtc gaaggaggtg cttctcgcgg agaccgcggg
481 acccgccgtg ccgagccggg agggccgtag gggccctgag atgccgagcg gtgcccgggc
541 ccgcttacct gcaccgcttg ctccgagccg cggggtccgc ctgctaggcc tgcggaaaac
601 gtcctagcga cactcggccc gcgggccccg aggtgcgccc gggaggcgcg agcccgcgtc
661 cggaaggcag ccaggcggcg ggcgcggggc gggctgtttt gcattatgtg cggctcggcc
721 ctggcttttt ttaccgctgc atttgtctgc ctgcaaaacg accggcgagg tcccgcctcg
781 ttcctctggg cagcctgggt gttttcactt gttcttggac tgggccaagg tgaagacaat
841 agatgtgcat cttcaaatgc agcatcctgt gccaggtgcc ttgcgctggg tccagaatgt
901 ggatggtgtg ttcaagagga tttcatttca ggtggatcaa gaagtgaacg ttgtgatatt
961 gtttccaatt taataagcaa aggctgctca gttgattcaa tagaataccc atctgtgcat
1021 gttataatac ccactgaaaa tgaaattaat acccaggtga caccaggaga agtgtctatc
1081 cagctgcgtc caggagccga agctaatttt atgctgaaag ttcatcctct gaagaaatat
1141 cctgtggatc tttattatct tgttgatgtc tcagcatcaa tgcacaataa tatagaaaaa
1201 ttaaattccg ttggaaacga tttatctaga aaaatggcat ttttctcccg tgactttcgt
1261 cttggatttg gctcatacgt tgataaaaca gtttcaccat acattagcat ccaccccgaa
1321 aggattcata atcaatgcag tgactacaat ttagactgca tgcctcccca tggatacatc
1381 catgtgctgt ctttgacaga gaacatcact gagtttgaga aagcagttca tagacagaag
1441 atctctggaa acatagatac accagaagga ggttttgacg ccatgcttca ggcagctgtc
1501 tgtgaaagtc atatcggatg gcgaaaagag gctaaaagat tgctgctggt gatgacagat
1561 cagacgtctc atctcgctct tgatagcaaa ttggcaggca tagtggtgcc caatgacgga
1621 aactgtcatc tgaaaaacaa cgtctatgtc aaatcgacaa ccatggaaca cccctcacta
1681 ggccaacttt cagagaaatt aatagacaac aacattaatg tcatctttgc agttcaagga
1741 aaacaatttc attggtataa ggatcttcta cccctcttgc caggcaccat tgctggtgaa
1801 atagaatcaa aggctgcaaa cctcaataat ttggtagtgg aagcctatca gaagctcatt
1861 tcagaagtga aagttcaggt ggaaaaccag gtacaaggca tctattttaa cattaccgcc
1921 atctgtccag atgggtccag aaagccaggc atggaaggat gcagaaacgt gacgagcaat
1981 gatgaagtat gtgggtgtgc atttttccct tttaaaataa actaagttgt ttggcgtact
2041 ttcttacaga aaaaaaaaaa aaaaaaaa
//