LOCUS BC002599 825 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens corticotropin releasing hormone, mRNA (cDNA clone
MGC:1770 IMAGE:3160933), complete cds.
ACCESSION BC002599
VERSION BC002599.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 825)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 825)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002599.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: j Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503040.
FEATURES Location/Qualifiers
source 1..825
/db_xref="H-InvDB:HIT000031024"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1770 IMAGE:3160933"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..825
/gene="CRH"
/gene_synonym="CRF"
/db_xref="GeneID:1392"
/db_xref="HGNC:HGNC:2355"
/db_xref="MIM:122560"
CDS 179..769
/gene="CRH"
/gene_synonym="CRF"
/codon_start=1
/product="corticotropin releasing hormone"
/protein_id="AAH02599.1"
/db_xref="GeneID:1392"
/db_xref="HGNC:HGNC:2355"
/db_xref="MIM:122560"
/translation="MRLPLLVSAGVLLVALLPCPPCRALLSRGPVPGARQAPQHPQPL
DFFQPPPQSEQPQQPQARPVLLRMGEEYFLRLGNLNKSPAAPLSPASSLLAGGSGSRP
SPEQATANFFRVLLQQLLLPRRSLDSPAALAERGARNALGGHQEAPERERRSEEPPIS
LDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK"
BASE COUNT 185 a 270 c 250 g 120 t
ORIGIN
1 cagagaccaa gtccattgag agactgaggg gaaagagagg agagaaagaa aaagagagtg
61 ggaacagtaa agagaaagga agacaacctc cagagaaagc ccccggagac gtctctctgc
121 agagaggcgg cagcacccgg ctcacctgcg aagcgcctgg gaagcgagtg cccctaacat
181 gcggctgccg ctgcttgtgt ccgcgggagt cctgctggtg gctctcctgc cctgcccgcc
241 atgcagggcg ctcctgagcc gcgggccggt cccgggagct cggcaggcgc cgcagcaccc
301 tcagcccttg gatttcttcc agccgccgcc gcagtccgag cagccccagc agccgcaggc
361 tcggccggtc ctgctccgca tgggagagga gtacttcctc cgcctgggga acctcaacaa
421 gagcccggcc gctccccttt cgcccgcctc ctcgctcctc gccggaggca gcggcagccg
481 cccttcgccg gaacaggcga ccgccaactt tttccgcgtg ttgctgcagc agctgctgct
541 gcctcggcgc tcgctcgaca gccccgcggc tctcgcggag cgcggcgcta ggaatgccct
601 cggcggccac caggaggcac cggagagaga aaggcggtcc gaggagcctc ccatctccct
661 ggatctcacc ttccacctcc tccgggaagt cttggaaatg gccagggccg agcagttagc
721 acagcaagct cacagcaaca ggaaactcat ggagattatt gggaaataaa acggtgcgtt
781 tggccaaaaa gaatctgcat ttagcacaaa aaaaaaaaaa aaaaa
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