LOCUS BC002577 1219 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens proteasome (prosome, macropain) subunit, alpha type,
1, mRNA (cDNA clone MGC:1667 IMAGE:3140784), complete cds.
ACCESSION BC002577
VERSION BC002577.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1219)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1219)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002577.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: d Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23110933.
FEATURES Location/Qualifiers
source 1..1219
/db_xref="H-InvDB:HIT000031005"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1667 IMAGE:3140784"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_9"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1219
/gene="PSMA1"
/gene_synonym="HC2"
/gene_synonym="MGC14542"
/gene_synonym="MGC14575"
/gene_synonym="MGC14751"
/gene_synonym="MGC1667"
/gene_synonym="MGC21459"
/gene_synonym="MGC22853"
/gene_synonym="MGC23915"
/gene_synonym="NU"
/gene_synonym="PROS30"
/db_xref="GeneID:5682"
/db_xref="HGNC:HGNC:9530"
/db_xref="MIM:602854"
CDS 66..857
/gene="PSMA1"
/gene_synonym="HC2"
/gene_synonym="MGC14542"
/gene_synonym="MGC14575"
/gene_synonym="MGC14751"
/gene_synonym="MGC1667"
/gene_synonym="MGC21459"
/gene_synonym="MGC22853"
/gene_synonym="MGC23915"
/gene_synonym="NU"
/gene_synonym="PROS30"
/codon_start=1
/product="proteasome (prosome, macropain) subunit, alpha
type, 1"
/protein_id="AAH02577.1"
/db_xref="GeneID:5682"
/db_xref="HGNC:HGNC:9530"
/db_xref="MIM:602854"
/translation="MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHA
VLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRP
LPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMS
IGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKD
LEFTIYDDDDVSPFLEGLEERPQRKAQPAQPADEPAEKADEPMEH"
BASE COUNT 388 a 230 c 254 g 347 t
ORIGIN
1 ctttcggcag cacctccttg attctcagtt ttgctggagg ccgcaaccag gcccgcgccg
61 ccaccatgtt tcgaaatcag tatgacaatg atgtcactgt ttggagcccc cagggcagga
121 ttcatcaaat tgaatatgca atggaagctg ttaaacaagg ttcagccaca gttggtctga
181 aatcaaaaac tcatgcagtt ttggttgcat tgaaaagggc gcaatcagag cttgcagctc
241 atcagaaaaa aattctccat gttgacaacc atattggtat ctcaattgcg gggcttactg
301 ctgatgctag actgttatgt aattttatgc gtcaggagtg tttggattcc agatttgtat
361 tcgatagacc actgcctgtg tctcgtcttg tatctctaat tggaagcaag acccagatac
421 caacacaacg atatggccgg agaccatatg gtgttggtct ccttattgct ggttatgatg
481 atatgggccc tcacattttc caaacctgtc catctgctaa ctattttgac tgcagagcca
541 tgtccattgg agcccgttcc caatcagctc gtacttactt ggagagacat atgtctgaat
601 ttatggagtg taatttaaat gaactagtta aacatggtct gcgtgcctta agagagacgc
661 ttcctgcaga acaggacctg actacaaaga atgtttccat tggaattgtt ggtaaagact
721 tggagtttac aatctatgat gatgatgatg tgtctccatt cctggaaggt cttgaagaaa
781 gaccacagag aaaggcacag cctgctcaac ctgctgatga acctgcagaa aaggctgatg
841 aaccaatgga acattaagtg ataagccagt ctatatatgt attatcaaat atgtaagaat
901 acaggcacca catactgatg acaataatct atactttgaa ccaaaagttg cagagtggtg
961 gaatgctatg ttttaggaat cagtccagat gtgagttttt tccaagcaac ctcactgaaa
1021 cctatataat ggaatacatt tttctttgaa agggtctgta taatcatttt ctagaaagta
1081 tgggtatcta tactaatgtt tttatatgaa gaacataggt gtctttgtgg ttttaaagac
1141 aactgtgaaa taaaattgtt tcaccgcctg gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1201 aaaaaaaaaa aaaaaaaaa
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