LOCUS BC002487 1508 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens tumor susceptibility gene 101, mRNA (cDNA clone
MGC:1317 IMAGE:3350039), complete cds.
ACCESSION BC002487
VERSION BC002487.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1508)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1508)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: p Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18765712.
FEATURES Location/Qualifiers
source 1..1508
/db_xref="H-InvDB:HIT000030933"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1317 IMAGE:3350039"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1508
/gene="TSG101"
/gene_synonym="VPS23"
/db_xref="GeneID:7251"
/db_xref="HGNC:HGNC:15971"
/db_xref="MIM:601387"
CDS 85..1257
/gene="TSG101"
/gene_synonym="VPS23"
/codon_start=1
/product="tumor susceptibility gene 101"
/protein_id="AAH02487.1"
/db_xref="GeneID:7251"
/db_xref="HGNC:HGNC:15971"
/db_xref="MIM:601387"
/translation="MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVF
NDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKH
VDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPN
TSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRD
GTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTR
LDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAE
ENAIEDTILYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY"
BASE COUNT 441 a 340 c 326 g 401 t
ORIGIN
1 tgtgcgattg tgtgggacgg tctggggcag cccagcagcg gctgaccctc tgcctgcggg
61 gaagggagtc gccaggcggc cgtcatggcg gtgtcggaga gccagctcaa gaaaatggtg
121 tccaagtaca aatacagaga cctaactgta cgtgaaactg tcaatgttat tactctatac
181 aaagatctca aacctgtttt ggattcatat gtttttaacg atggcagttc cagggaacta
241 atgaacctca ctggaacaat ccctgtgcct tatagaggta atacatacaa tattccaata
301 tgcctatggc tactggacac atacccatat aatcccccta tctgttttgt taagcctact
361 agttcaatga ctattaaaac aggaaagcat gttgatgcaa atgggaagat atatcttcct
421 tatctacatg aatggaaaca cccacagtca gacttgttgg ggcttattca ggtcatgatt
481 gtggtatttg gagatgaacc tccagtcttc tctcgtccta tttcggcatc ctatccgcca
541 taccaggcaa cggggccacc aaatacttcc tacatgccag gcatgccagg tggaatctct
601 ccatacccat ccggataccc tcccaatccc agtggttacc caggctgtcc ttacccacct
661 ggtggtccat atcctgccac aacaagttct cagtaccctt ctcagcctcc tgtgaccact
721 gttggtccca gtagggatgg cacaatcagc gaggacacca tccgagcctc tctcatctct
781 gcggtcagtg acaaactgag atggcggatg aaggaggaaa tggatcgtgc ccaggcagag
841 ctcaatgcct tgaaacgaac agaagaagac ctgaaaaagg gtcaccagaa actggaagag
901 atggttaccc gtttagatca agaagtagcc gaggttgata aaaacataga acttttgaaa
961 aagaaggatg aagaactcag ttctgctctg gaaaaaatgg aaaatcagtc tgaaaacaat
1021 gatatcgatg aagttatcat tcccacagct cccttataca aacagatcct gaatctgtat
1081 gcagaagaaa acgctattga agacactatc ctttacttgg gagaagcctt gagaaggggc
1141 gtgatagacc tggatgtctt cctgaagcat gtacgtcttc tgtcccgtaa acagttccag
1201 ctgagggcac taatgcaaaa agcaagaaag actgccggtc tcagtgacct ctactgactt
1261 ctctgatacc agctggaggt tgagctcttc ttaaagtatt cttctcttcc ttttatcagt
1321 aggtgcccag aataagttat tgcagtttat cattcaagtg taaaatattt tgaatcaata
1381 atatattttc tgttttcttt tggtaaagac tggcttttat taatgcactt tctatcctct
1441 gtaaactttt tgtgctgaat gttgggactg ctaaataaaa tttgttgcat aaaaaaaaaa
1501 aaaaaaaa
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