LOCUS BC002477 3171 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens dehydrogenase E1 and transketolase domain containing
1, mRNA (cDNA clone MGC:3090 IMAGE:3347913), complete cds.
ACCESSION BC002477
VERSION BC002477.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3171)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3171)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002477.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: j Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38788379.
FEATURES Location/Qualifiers
source 1..3171
/db_xref="H-InvDB:HIT000030924"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3090 IMAGE:3347913"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3171
/gene="DHTKD1"
/gene_synonym="DKFZP762M115"
/gene_synonym="KIAA1630"
/gene_synonym="MGC3090"
/db_xref="GeneID:55526"
/db_xref="HGNC:HGNC:23537"
CDS 63..2822
/gene="DHTKD1"
/gene_synonym="DKFZP762M115"
/gene_synonym="KIAA1630"
/gene_synonym="MGC3090"
/codon_start=1
/product="dehydrogenase E1 and transketolase domain
containing 1"
/protein_id="AAH02477.1"
/db_xref="GeneID:55526"
/db_xref="HGNC:HGNC:23537"
/translation="MASATAAAARRGLGRALPLLWRGYQTERGVYGYRPRKPESREPQ
GALERPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQGPFHT
AGLLNMGKEEASLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTT
EERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVI
IGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLDFGAH
HPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSLQDGDYSPDNSAQPGDRVICLQVHGDA
SFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGC
AIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYK
IIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAH
WQGLAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDG
IKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQETDDTYIPLNHMD
PNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISG
GEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPT
TPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVD
PKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHV
KDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDIL
AKTFA"
BASE COUNT 788 a 818 c 851 g 714 t
ORIGIN
1 cagggccggt gggatcccct cgggctcccg ccttagcatg ctggccggga catctggtga
61 acatggcctc tgctactgcg gcagcagcac gacggggcct cggccgggct ctccctctcc
121 tctggcgtgg ctaccagacc gagcggggcg tttacggcta ccggccgagg aagcccgaga
181 gccgcgagcc ccagggcgcc ctggagcgcc ccccagttga tcatggcctt gccaggttgg
241 tgacagtata ttgtgagcat ggtcataaag ctgccaaaat caaccccctc ttcaccggac
301 aagccctgct ggagaatgtg cctgaaatcc aagccctggt gcagacactg cagggaccct
361 tccacacggc aggattattg aacatgggga aggaagaggc ctcacttgag gaagtgttag
421 tctatctcaa tcaaatctac tgtgggcaga tttctattga aacctcccaa cttcagagcc
481 aggatgagaa agactggttt gccaagcggt ttgaggaact gcaaaaggag acgtttacca
541 cagaagagcg aaaacatctg tcgaaactaa tgctggaatc tcaggagttt gaccactttc
601 tggccaccaa gttctcgaca gtgaagcgat atggaggcga aggggctgaa agcatgatgg
661 gctttttcca cgagctgctg aaaatgtcgg cctacagcgg gatcactgat gtcattattg
721 ggatgcccca tagagggagg ctgaatttat tgacaggcct tctgcagttc cctccagagc
781 tgatgttccg taaaatgcga ggcttaagtg aatttccaga gaatttctca gccactggag
841 acgtcctgtc tcacctgacc tcctctgtgg acctggactt tggggcgcac catcccctcc
901 atgtgacaat gttgcccaat ccctcgcacc tggaggccgt caaccccgtg gccgtgggca
961 aaactcgcgg caggcagcag tctctccaag acggcgatta ctctccagac aactcagccc
1021 agccggggga cagggtcatt tgcttacagg tccatggtga tgcttctttc tgtggtcaag
1081 ggattgttcc tgaaacattc acgctgtcca atctcccaca tttcagaatt ggtgggagtg
1141 tgcatttgat tgttaataac cagctgggtt acaccactcc agctgaaaga ggaaggtctt
1201 ctttatactg cagtgatatt gggaagcttg tgggctgtgc catcatccat gtcaatggag
1261 acagcccaga ggaagtggtc cgtgccacac gactggcttt tgaataccaa cgccagttcc
1321 gcaaggatgt gattattgat ctgttgtgct acaggcagtg gggccacaat gagctggatg
1381 agccattcta caccaacccc atcatgtaca aaatcatcag agctcgaaag agcattccag
1441 acacatatgc agagcacctc attgctggcg gactcatgac gcaggaggag gtgtctgaaa
1501 taaaatcctc ctactatgcc aagttgaatg atcacttaaa taacatggcc cactacaggc
1561 cccctgccct gaacctgcag gcccactggc agggcctggc tcagccagaa gcgcaaatca
1621 ccacctggag tacaggtgtg cccctcgacc tcctgcggtt tgttggcatg aagtctgtag
1681 aggtgccaag agagctgcag atgcacagtc acctgctgaa gacacatgtt cagtccagaa
1741 tggagaagat gatggacgga atcaagctag actgggccac cgcggaagct cttgccttgg
1801 gttctttact tgctcaaggt tttaatgttc gtctaagtgg ccaagatgtt ggtcgtggaa
1861 ctttcagtca gaggcatgca atggtggttt gccaggagac ggatgacacc tacatccccc
1921 tgaaccatat ggacccaaat cagaaggggt ttctagaggt cagcaacagc cccctgtcag
1981 aagaggccgt cctgggattc gaatatggga tgagcattga gagcccaaag ttactgcccc
2041 tgtgggaggc acagtttggc gatttcttca atggtgccca gatcatcttt gacacattca
2101 tctctggagg agaggccaag tggctcctac aaagcggcat tgtcatcctc cttccacatg
2161 gctacgatgg ggctgggcca gaccactcat cctgtcgaat agagcgtttc ctgcagatgt
2221 gtgacagtgc ggaagagggg gtggacggag acactgtgaa catgtttgtg gttcacccaa
2281 caactcctgc acagtatttc cacttgctta ggagacagat ggtccggaac ttcagaaaac
2341 cactcattgt tgcttcccct aagatgttac tcaggctccc ggcagccgtg tcaactcttc
2401 aagaaatggc accaggaaca acatttaacc cggtcattgg tgattcatct gtggatccaa
2461 aaaaggttaa gaccctcgtg ttctgctccg gcaaacattt ctactccctg gtgaaacaaa
2521 gagaatctct gggggccaag aagcatgact ttgccatcat ccgagtagag gaactctgcc
2581 ccttcccgtt ggattcttta cagcaagaga tgagcaaata caaacatgtt aaagatcata
2641 tttggagtca ggaggaacct cagaacatgg gtccgtggtc gtttgtttct ccaaggtttg
2701 aaaagcagct ggcctgcaag ctccgtctgg tgggccggcc ccctttgcca gtacccgctg
2761 taggaattgg cacagttcac ttgcaccagc atgaagatat cctcgccaag accttcgctt
2821 gatgatgact tttgaagaaa cactatttct ctttaagaaa atggccatta aggccgggtg
2881 gggtggcaca tgcctgtaat cccagcactt tgggaggcca aggctggtgg atcacctgag
2941 gtcaggagtt cgagaccagc ctggccaaca cggtgaaacc ccgcctctac taaaaataca
3001 aaaaatagcc gggtgtggtg gtgggcacct gtgatcccag cttcctggga ggctgaggca
3061 agagaatcgc ttgaatctgg gaggcggagg ttgcagtgag ccaggatcac accattgctg
3121 tccagcctgg gtgacagagc aagactgcgt ttcaaaaaaa aaaaaaaaaa a
//