LOCUS BC002433 1951 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens transketolase, mRNA (cDNA clone MGC:2211
IMAGE:3346980), complete cds.
ACCESSION BC002433
VERSION BC002433.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1951)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1951)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002433.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: e Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4507520.
FEATURES Location/Qualifiers
source 1..1951
/db_xref="H-InvDB:HIT000050406"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2211 IMAGE:3346980"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1951
/gene="TKT"
/gene_synonym="TKT1"
/db_xref="GeneID:7086"
/db_xref="HGNC:HGNC:11834"
/db_xref="MIM:606781"
CDS 460..1833
/gene="TKT"
/gene_synonym="TKT1"
/codon_start=1
/product="TKT protein"
/protein_id="AAH02433.1"
/db_xref="GeneID:7086"
/db_xref="HGNC:HGNC:11834"
/db_xref="MIM:606781"
/translation="MAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFG
WHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAE
QIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALA
KLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVP
FCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPT
STVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKD
DQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILT
VEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAV
RGLITKA"
BASE COUNT 468 a 578 c 548 g 357 t
ORIGIN
1 cgcctgtcgc cgcgggagca gccgctatct ctgtgtgtcc gcgtgtgcgc ccggtccccg
61 cctgccgcac catggagagc taccacaagc ctgaccagca gaagctgcag gccttgaagg
121 acacggccaa ccgcctacgt atcagctcca tccaggccac cactgcggcg ggctctggcc
181 accccacgtc atgctgcagc gccgcagaga tcatggctgt cctctttttc cacaccatgc
241 gctacaagtc ccaggacccc cggaatccgc acaatgaccg ctttgtgctc tccaagggcc
301 atgcagctcc catcctctac gcggtctggg ctgaagctgg tttcctggcc gaggcggagc
361 tgctgaacct gaggaagatc agctccgctt gtgggatggc ctacaccggc aaatacttcg
421 acaaggccag ctaccgagtc tattgcttgc tgggaggcca tggccttcgc cagcatctat
481 aagctggaca accttgtggc cattctagac atcaatcgcc tgggccagag tgacccggcc
541 ccgctgcagc accagatgga catctaccag aagcggtgcg aggccttcgg ttggcatgcc
601 atcatcgtgg atggacacag cgtggaggag ctgtgcaagg cctttggcca ggccaagcac
661 cagccaacag ccatcattgc caagaccttc aagggccgag ggatcacggg ggtagaagat
721 aaggagtctt ggcatgggaa gcccctcccc aaaaacatgg ctgagcagat catccaggag
781 atctacagcc agatccagag caaaaagaag atcctggcaa cccctccaca ggaggacgca
841 ccctcagtgg acattgccaa catccgcatg cccagcctgc ccagctacaa agttggggac
901 aagatagcca cccgcaaggc ctacgggcag gcactggcca agctgggcca tgccagtgac
961 cgcatcatcg ccctggatgg ggacaccaaa aattccacct tctcggagat cttcaaaaag
1021 gagcacccgg accgcttcat cgagtgctac attgccgagc agaacatggt gagcatcgcg
1081 gtgggctgtg ccacccgcaa caggacggtg cccttctgca gcacttttgc agccttcttc
1141 acgcgggcct ttgaccagat tcgcatggcc gccatctccg agagcaacat caacctctgc
1201 ggctcccact gcggcgtttc catcggggaa gacgggccct cccagatggc cctagaagat
1261 ctggctatgt ttcggtcagt ccccacatca actgtctttt acccaagtga tggcgttgct
1321 acagagaagg cagtggaact agccgccaat acaaagggta tctgcttcat ccggaccagc
1381 cgcccagaaa atgccatcat ctataacaac aatgaggact tccaggtcgg acaagccaag
1441 gtggtcctga agagcaagga tgaccaggtg accgttatcg gggctggggt gaccctgcac
1501 gaggccttgg ccgctgccga actgctgaag aaagaaaaga tcaacatccg cgtgctggac
1561 cccttcacca tcaagcccct ggacagaaaa ctcattctcg acagcgctcg tgccaccaag
1621 ggcaggatcc tcaccgtgga ggaccattat tatgaaggtg gcattggtga ggctgtgtcc
1681 agtgcagtag tgggcgagcc tggcatcact gtcacccacc tggcagttaa ccgggtacca
1741 agaagtggga agccagctga gctgctgaag atgtttggta tcgacaggga tgccattgca
1801 caagctgtga ggggcctcat caccaaggcc tagggcgggt atgaagtgtg gggcgggggt
1861 ctatacattc ctgagattct gggaaaggtg ctcaaagatg tactgagagg aggggtaaat
1921 atatgttttg agaaaaaaaa aaaaaaaaaa a
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