LOCUS BC002397 3281 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens polypyrimidine tract binding protein 1, mRNA (cDNA
clone MGC:8461 IMAGE:2821531), complete cds.
ACCESSION BC002397
VERSION BC002397.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3281)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3281)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002397.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: f Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 28558997.
FEATURES Location/Qualifiers
source 1..3281
/db_xref="H-InvDB:HIT000030860"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8461 IMAGE:2821531"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3281
/gene="PTBP1"
/gene_synonym="HNRNPI"
/gene_synonym="HNRPI"
/gene_synonym="MGC10830"
/gene_synonym="MGC8461"
/gene_synonym="pPTB"
/gene_synonym="PTB-1"
/gene_synonym="PTB-T"
/gene_synonym="PTB2"
/gene_synonym="PTB3"
/gene_synonym="PTB4"
/db_xref="GeneID:5725"
/db_xref="HGNC:HGNC:9583"
/db_xref="MIM:600693"
CDS 74..1747
/gene="PTBP1"
/gene_synonym="HNRNPI"
/gene_synonym="HNRPI"
/gene_synonym="MGC10830"
/gene_synonym="MGC8461"
/gene_synonym="pPTB"
/gene_synonym="PTB-1"
/gene_synonym="PTB-T"
/gene_synonym="PTB2"
/gene_synonym="PTB3"
/gene_synonym="PTB4"
/codon_start=1
/product="polypyrimidine tract binding protein 1"
/protein_id="AAH02397.1"
/db_xref="GeneID:5725"
/db_xref="HGNC:HGNC:9583"
/db_xref="MIM:600693"
/translation="MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDS
KKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMN
TEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSG
NLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTK
NNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT
RPDLPSGDSQPSLDQTMAAAFGAPGIISASPYAGAGFPPTFAIPQAAGLSVPNVHGAL
APLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQR
VKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQ
GLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVK
GFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI"
BASE COUNT 720 a 1007 c 859 g 695 t
ORIGIN
1 ctcggagccg ttgggtcggt tcctgctatt ccggcgcctc cactccgtcc cccgcgggtc
61 tgctctgtgt gccatggacg gcattgtccc agatatagcc gttggtacaa agcggggatc
121 tgacgagctt ttctctactt gtgtcactaa cggaccgttt atcatgagca gcaactcggc
181 ttctgcagca aacggaaatg acagcaagaa gttcaaaggt gacagccgaa gtgcaggcgt
241 cccctctaga gtgatccaca tccggaagct ccccatcgac gtcacggagg gggaagtcat
301 ctccctgggg ctgccctttg ggaaggtcac caacctcctg atgctgaagg ggaaaaacca
361 ggccttcatc gagatgaaca cggaggaggc tgccaacacc atggtgaact actacacctc
421 ggtgacccct gtgctgcgcg gccagcccat ctacatccag ttctccaacc acaaggagct
481 gaagaccgac agctctccca accaggcgcg ggcccaggcg gccctgcagg cggtgaactc
541 ggtccagtcg gggaacctgg ccttggctgc ctcggcggcg gccgtggacg cagggatggc
601 gatggccggg cagagccccg tgctcaggat catcgtggag aacctcttct accctgtgac
661 cctggatgtg ctgcaccaga ttttctccaa gttcggcaca gtgttgaaga tcatcacctt
721 caccaagaac aaccagttcc aggccctgct gcagtatgcg gaccccgtga gcgcccagca
781 cgccaagctg tcgctggacg ggcagaacat ctacaacgcc tgctgcacgc tgcgcatcga
841 cttttccaag ctcaccagcc tcaacgtcaa gtacaacaat gacaagagcc gtgactacac
901 acgcccagac ctgccttccg gggacagcca gccctcgctg gaccagacca tggccgcggc
961 cttcggtgca cctggtataa tctcagcctc tccgtatgca ggagctggtt tccctcccac
1021 ctttgccatt cctcaagctg caggcctttc cgttccgaac gtccacggcg ccctggcccc
1081 cctggccatc ccctcggcgg cggcggcagc tgcggcggca ggtcggatcg ccatcccggg
1141 cctggcgggg gcaggaaatt ctgtattgct ggtcagcaac ctcaacccag agagagtcac
1201 accccaaagc ctctttattc ttttcggcgt ctacggtgac gtgcagcgcg tgaagatcct
1261 gttcaataag aaggagaacg ccctagtgca gatggcggac ggcaaccagg cccagctggc
1321 catgagccac ctgaacgggc acaagctgca cgggaagccc atccgcatca cgctctcgaa
1381 gcaccagaac gtgcagctgc cccgcgaggg ccaggaggac cagggcctga ccaaggacta
1441 cggcaactca cccctgcacc gcttcaagaa gccgggctcc aagaacttcc agaacatatt
1501 cccgccctcg gccacgctgc acctctccaa catcccgccc tcagtctccg aggaggatct
1561 caaggtcctg ttttccagca atgggggcgt cgtcaaagga ttcaagttct tccagaagga
1621 ccgcaagatg gcactgatcc agatgggctc cgtggaggag gcggtccagg ccctcattga
1681 cctgcacaac cacgacctcg gggagaacca ccacctgcgg gtctccttct ccaagtccac
1741 catctagggg cacaggcccc cacggccggg ccccctggcg acaacttcca tcattccaga
1801 gaaaagccac tttaaaaaca gctgaagtga ccttagcaga ccagagattt tattttttta
1861 aagagaaatc agtttacctg tttttaaaaa aattaaatct agttcacctt gctcaccctg
1921 cggtgacagg gacagctcag gctcttggtg actgtggcag cgggagttcc cggccctcca
1981 cacccggggc cagaccctcg gggccatgcc ttggtggggc ctgtgtcggg cgtggggcct
2041 gcaggtgggc gccccgacca cgacttggct tccttgtgcc ttaaaaaacc tgccttcctg
2101 cagccacaca cccacccggg gtgtcctggg gacccaaggg gtgggggggt cacaccagag
2161 agaggcaggg ggcctggccg gctcctgcag gatcatgcag ctggggcgcg gcggccgcgg
2221 ctgcgacacc ccaaccccag ccctctaatc aagtcacgtg attctccctt caccccgccc
2281 ccagggcctt cccttctgcc cccaggcggg ctccccgctg ctccagctgc ggagctggtc
2341 gacataatct ctgtattata tactttgcag ttgcagacgt ctgtgcctag caatatttcc
2401 agttgaccaa atattctaat cttttttcat ttatatgcaa aagaaatagt tttaagtaac
2461 tttttatagc aagatgatac aatggtatga gtgtaatcta aacttccttg tggtattacc
2521 ttgtatgctg ttacttttat tttattcctt gtaattaagt cacaggcagg acccagtttc
2581 cagagagcag gcggggccgc ccagtgggtc aggcacaggg agccccggtc ctatcttaga
2641 gcccctgagc ttcagggaag gggcgggcgt gtcgccgcct ctggcatcgc ctccggttgc
2701 cttacaccac gccttcacct gcagtcgcct agaaaacttg ctctcaaact tcagggtttt
2761 ttcttccttc aaattttgga ccaaagtctc atttctgtgt tttgcctgcc tctgatgctg
2821 ggacccggaa ggcgggcgct cctcctgtct ttgtgctctt tctaccgccc ccgcgtcctg
2881 tcccgggggc tctcctagga tcccctttcc gtaaaagcgt gtaacaaggg tgtaaatatt
2941 tataattttt tatacctgtt gtgagacccg aggggcggcg gcgcggtttt ttatggtgac
3001 acaaatgtat attttgctaa cagcaattcc aggctcagta ttgtgaccgc ggagccacag
3061 gggaccccac gcacattccg ttgccttacc cgatggcttg tgacgcggag agaaccgatt
3121 aaaaccgttt gagaaactcc tcccttgtct agccctgtgt tcgctgtgga cgctgtagag
3181 gcaggttggc cagtctgtac ctggacttcg aataaatctt ctgtatcctc aaaaaaaaaa
3241 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//