LOCUS BC002354 2076 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens 5-hydroxytryptamine (serotonin) receptor 3A, mRNA
(cDNA clone MGC:8469 IMAGE:2821710), complete cds.
ACCESSION BC002354
VERSION BC002354.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2076)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2076)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002354.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: g Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47519823.
FEATURES Location/Qualifiers
source 1..2076
/db_xref="H-InvDB:HIT000030821"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8469 IMAGE:2821710"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2076
/gene="HTR3A"
/gene_synonym="5-HT-3"
/gene_synonym="5-HT3A"
/gene_synonym="5-HT3R"
/gene_synonym="5HT3R"
/db_xref="GeneID:3359"
/db_xref="HGNC:HGNC:5297"
/db_xref="MIM:182139"
CDS 68..1504
/gene="HTR3A"
/gene_synonym="5-HT-3"
/gene_synonym="5-HT3A"
/gene_synonym="5-HT3R"
/gene_synonym="5HT3R"
/codon_start=1
/product="5-hydroxytryptamine (serotonin) receptor 3A"
/protein_id="AAH02354.1"
/db_xref="GeneID:3359"
/db_xref="HGNC:HGNC:5297"
/db_xref="MIM:182139"
/translation="MLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTN
YRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF
DNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLD
IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYF
REFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSF
KITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQD
LQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQ
DFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLD
KLLFHIYLLAVLAYSITLVMLWSIWQYA"
BASE COUNT 465 a 604 c 529 g 478 t
ORIGIN
1 gcaagctggc ccttggtggg cctcgtcctg agcactcgga ggcactccta tgcttggaaa
61 gctcgctatg ctgctgtggg tccagcaggc gctgctcgcc ttgctcctcc ccacactcct
121 ggcacaggga gaagccagga ggagccgaaa caccaccagg cccgctctgc tgaggctgtc
181 ggattacctt ttgaccaact acaggaaggg tgtgcgcccc gtgagggact ggaggaagcc
241 aaccaccgta tccattgacg tcattgtcta tgccatcctc aacgtggatg agaagaatca
301 ggtgctgacc acctacatct ggtaccggca gtactggact gatgagtttc tccagtggaa
361 ccctgaggac tttgacaaca tcaccaagtt gtccatcccc acggacagca tctgggtccc
421 ggacattctc atcaatgagt tcgtggatgt ggggaagtct ccaaatatcc cgtacgtgta
481 tattcggcat caaggcgaag ttcagaacta caagcccctt caggtggtga ctgcctgtag
541 cctcgacatc tacaacttcc ccttcgatgt ccagaactgc tcgctgacct tcaccagttg
601 gctgcacacc atccaggaca tcaacatctc tttgtggcgc ttgccagaaa aggtgaaatc
661 cgacaggagt gtcttcatga accagggaga gtgggagttg ctgggggtgc tgccctactt
721 tcgggagttc agcatggaaa gcagtaacta ctatgcagaa atgaagttct atgtggtcat
781 ccgccggcgg cccctcttct atgtggtcag cctgctactg cccagcatct tcctcatggt
841 catggacatc gtgggcttct acctgccccc caacagtggc gagagggtct ctttcaagat
901 tacactcctc ctgggctact cggtcttcct gatcatcgtt tctgacacgc tgccggccac
961 tgccatcggc actcctctca ttggtgtcta ctttgtggtg tgcatggctc tgctggtgat
1021 aagtttggcc gagaccatct tcattgtgcg gctggtgcac aagcaagacc tgcagcagcc
1081 cgtgcctgct tggctgcgtc acctggttct ggagagaatc gcctggctac tttgcctgag
1141 ggagcagtca acttcccaga ggcccccagc cacctcccaa gccaccaaga ctgatgactg
1201 ctcagccatg ggaaaccact gcagccacat gggaggaccc caggacttcg agaagagccc
1261 gagggacaga tgtagccctc ccccaccacc tcgggaggcc tcgctggcgg tgtgtgggct
1321 gctgcaggag ctgtcctcca tccggcaatt cctggaaaag cgggatgaga tccgagaggt
1381 ggcccgagac tggctgcgcg tgggctccgt gctggacaag ctgctattcc acatttacct
1441 gctggcggtg ctggcctaca gcatcaccct ggttatgctc tggtccatct ggcagtacgc
1501 ttgagtgggt acagcccagt ggaggagggg gtacagtcct ggttaggtgg ggacagagga
1561 tttctgctta ggcccctcag gacccaggga atgccaggga cattttcaag acacagacaa
1621 agtcccgtgc cctgtttcca atgccaattc atctcagcaa tcacaagcca aggtctgaac
1681 ccttccacca aaaactgggt gttcaaggcc cttacaccct tgtcccaccc ccagcagctc
1741 accatggctt taaaacatgc tctcttagat caggagaaac tcgggcactc cctaagtcca
1801 ctctagttgt ggacttttcc ccattgaccc tcacctgaat aagggacttt ggaattctgc
1861 ttctctttca caactttgct tttaggttga aggcaaaacc aactctctac tacacaggcc
1921 tgataactct gtacgaggct tctctaaccc ctagtgtctt ttttttcttc acctcacttg
1981 tggcagcttc cctgaacact catcccccat cagatgatgg gagtgggaag aataaaatgc
2041 agtgaaaccc taaaaaaaaa aaaaaaaaaa aaaaaa
//