LOCUS BC001870 1660 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2B, subunit 4
delta, 67kDa, mRNA (cDNA clone MGC:1204 IMAGE:3534267), complete
cds.
ACCESSION BC001870
VERSION BC001870.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1660)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1660)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-JAN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: i Column: 17.
FEATURES Location/Qualifiers
source 1..1660
/db_xref="H-InvDB:HIT000030709"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1204 IMAGE:3534267"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1660
/gene="EIF2B4"
/gene_synonym="DKFZp586J0119"
/gene_synonym="EIF-2B"
/gene_synonym="EIF2B"
/gene_synonym="EIF2Bdelta"
/db_xref="GeneID:8890"
/db_xref="HGNC:HGNC:3260"
/db_xref="MIM:606687"
CDS 2..1573
/gene="EIF2B4"
/gene_synonym="DKFZp586J0119"
/gene_synonym="EIF-2B"
/gene_synonym="EIF2B"
/gene_synonym="EIF2Bdelta"
/codon_start=1
/product="eukaryotic translation initiation factor 2B,
subunit 4 delta, 67kDa"
/protein_id="AAH01870.1"
/db_xref="GeneID:8890"
/db_xref="HGNC:HGNC:3260"
/db_xref="MIM:606687"
/translation="MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKK
QQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRA
ERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVK
KPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGL
VSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNA
IKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVIL
VYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAAS
YVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTD
AFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIP
CSSVPVVLRVKSSDQ"
BASE COUNT 447 a 414 c 458 g 341 t
ORIGIN
1 gatggctgct gtggccgtgg ctgttcgcga ggactcggga tccgggatga aggcggagct
61 tccccctggg cctggggcag tggggaggga aatgaccaaa gaagaaaagc tgcagcttcg
121 gaaggaaaag aaacagcaga agaagaaacg gaaggaagaa aagggggcag aaccagagac
181 tggctctgct gtatctgcag cccaatgtca agtaggccca accagagaac tgccagaatc
241 gggcattcag ttgggcactc ctcgggagaa agttccagct ggtcggagta aggccgaact
301 tcgggctgag cgtcgagcca agcaggaggc cgagcgggcc ctgaaacagg caagaaaagg
361 ggaacaagga ggaccacctc ctaaggccag ccccagcaca gctggagaaa ccccctcagg
421 agtgaagcgt ctccctgagt accctcaggt tgatgaccta cttctgagaa ggcttgttaa
481 aaaaccagag cgtcaacagg ttcctacacg aaaggattat ggatccaaag tcagtctctt
541 ctctcaccta ccccagtaca gcagacaaaa ctctctgacc cagtttatga gcatcccatc
601 ctctgtgatc cacccagcca tggtgcgact cggcctgcag tactcccagg gcctggtcag
661 tggctccaat gcccggtgta ttgccctgct tcgtgccttg cagcaggtga ttcaggatta
721 cacaacaccg cctaatgaag aactctccag ggatctagtg aataaactaa aaccctacat
781 gagcttcctg actcagtgcc gtcccctgtc agcgagcatg cacaacgcca tcaagttcct
841 taacaaggaa atcaccagtg tgggcagttc caagcgggaa gaggaggcca agtcagaact
901 tcgagcagcc attgatcggt atgtgcaaga gaagattgtg ctagcagctc aggcaatttc
961 acgctttgct taccagaaga tcagtaatgg agatgtgatc ctggtatatg gatgctcatc
1021 tctggtatca cgaattcttc aggaggcttg gacagagggc cggcggtttc gggtggtagt
1081 ggtggacagc cggccatggc tggaaggaag gcacacacta cgttctctag tccatgctgg
1141 tgtcccagcc tcctacctgc tgattcctgc agcctcctat gtgctcccag aggtttccaa
1201 ggtgctattg ggagctcatg cactcttggc caacgggtct gtgatgtcac gggtagggac
1261 agcacagtta gccctggtgg ctcgagccca taatgtacca gtgctggttt gctgtgaaac
1321 atacaagttc tgtgagcgtg tgcagactga tgcctttgtc tctaatgagc tagatgaccc
1381 tgatgatctg caatgtaagc ggggagaaca tgttgcgctg gctaactggc agaaccacgc
1441 atccctacgg ttgttgaatc tagtctatga tgtgactccc ccagagcttg tggatctggt
1501 gatcacggag ctggggatga tcccttgcag ttctgtacct gttgttctac gagtcaagag
1561 cagtgaccag tgacggggga aacacagggt taataaatgc catactccct accctcaaaa
1621 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaac
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