LOCUS BC001778 1263 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens uroporphyrinogen decarboxylase, mRNA (cDNA clone
MGC:1856 IMAGE:3542421), complete cds.
ACCESSION BC001778
VERSION BC001778.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1263)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1263)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (23-JAN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: c Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 71051615.
FEATURES Location/Qualifiers
source 1..1263
/db_xref="H-InvDB:HIT000030643"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1856 IMAGE:3542421"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1263
/gene="UROD"
/gene_synonym="PCT"
/db_xref="GeneID:7389"
/db_xref="HGNC:HGNC:12591"
/db_xref="MIM:176100"
CDS 29..1132
/gene="UROD"
/gene_synonym="PCT"
/codon_start=1
/product="uroporphyrinogen decarboxylase"
/protein_id="AAH01778.1"
/db_xref="GeneID:7389"
/db_xref="HGNC:HGNC:12591"
/db_xref="MIM:176100"
/translation="MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP
EFRETRAAQDFFSTCRSPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVP
GKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWT
LMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFE
SHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAG
YEVVGLDWTVAPKKARECVGKTVTLQVNLDPCALYASEEEIGQLVKQMLDDFGPHRYI
ANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN"
BASE COUNT 318 a 319 c 350 g 276 t
ORIGIN
1 ttgagctcgc agttacagac agctgaccat ggaagcgaat gggttgggac ctcagggttt
61 tccggagctg aagaatgaca cattcctgcg agcagcctgg ggagaggaaa cagactacac
121 tcccgtttgg tgcatgcgcc aggcaggccg ttacttacca gagtttaggg aaacccgggc
181 tgcccaggac tttttcagca cgtgtcgctc tcctgaggcc tgctgtgaac tgactctgca
241 gccactgcgt cgcttccctc tggatgctgc catcattttc tccgacatcc ttgttgtacc
301 ccaggcactg ggcatggagg tgaccatggt acctggcaaa ggacccagct tcccagagcc
361 attaagagaa gagcaggacc tagaacgcct acgggatcca gaagtggtag cctctgagct
421 aggctatgtg ttccaagcca tcacccttac ccgacaacga ctggctggac gtgtgccgct
481 gattggcttt gctggtgccc catggaccct gatgacatac atggttgagg gtggtggctc
541 aagcaccatg gctcaggcca agcgctggct ctatcagaga cctcaggcta gtcaccagct
601 gcttcgcatc ctcactgatg ctctggtccc atatctggta ggacaagtgg tggctggtgc
661 ccaggcattg cagctgtttg agtcccatgc agggcatctt ggcccacagc tcttcaacaa
721 gtttgcactg ccttacatcc gtgatgtggc caagcaagtg aaggccaggt tgcgggaggc
781 aggcctggca ccagtgccca tgatcatctt tgctaaggat gggcattttg ccctggagga
841 gctggcccaa gctggctatg aggtggttgg gcttgactgg acagtggccc caaagaaagc
901 ccgggagtgt gtggggaaga cggtgacatt gcaggtcaac ctggacccct gtgccttgta
961 tgcatctgag gaggagatcg ggcagttggt gaagcagatg ctggatgact ttggaccaca
1021 tcgctacatt gccaacctgg gccatgggct ttatcctgac atggacccag aacatgtggg
1081 cgcctttgtg gatgctgtgc ataaacactc acgtctgctt cgacagaact gagtgtatac
1141 ctttaccctc aagtaccact aacacagatg attgatcgtt tccaggacaa taaaagtttc
1201 ggagttgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1261 aaa
//