LOCUS BC001627 1907 bp mRNA linear HUM 19-JUN-2006
DEFINITION Homo sapiens 2-hydroxyacyl-CoA lyase 1, mRNA (cDNA clone MGC:1115
IMAGE:3538159), complete cds.
ACCESSION BC001627
VERSION BC001627.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1907)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1907)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-JAN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: d Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6912417.
FEATURES Location/Qualifiers
source 1..1907
/db_xref="H-InvDB:HIT000030528"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1115 IMAGE:3538159"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1907
/gene="HACL1"
/gene_synonym="2-HPCL"
/gene_synonym="HPCL2"
/gene_synonym="PHYH2"
/db_xref="GeneID:26061"
/db_xref="HGNC:HGNC:17856"
/db_xref="MIM:604300"
CDS 108..1844
/gene="HACL1"
/gene_synonym="2-HPCL"
/gene_synonym="HPCL2"
/gene_synonym="PHYH2"
/codon_start=1
/product="2-hydroxyacyl-CoA lyase 1"
/protein_id="AAH01627.1"
/db_xref="GeneID:26061"
/db_xref="HGNC:HGNC:17856"
/db_xref="MIM:604300"
/translation="MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIA
IAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNC
WPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIPFVIEKAVRSSIY
GRPGACYVDIPADFVNLQVNVNSIKYMERCMSPPISMAETSAVCTAASVIRNAKQPLL
IIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVGAARSRALQFADVI
VLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLE
ELDKTPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDC
FVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWII
CVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKEMLKFQDATAVVP
PMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLADTTKPSLINIMIEPQATRK
AQDFHWLTRSNM"
BASE COUNT 539 a 396 c 473 g 499 t
ORIGIN
1 cagaggtgca gtaccagagg tggcgtgctg ccgacttcgc gtttgccttg ctggatgatt
61 ccgcttgttt gccggctgcg tgagtgctta gagcttttcg gtggaagatg ccggacagta
121 acttcgcaga gcgcagcgag gagcaggtgt ctggtgctaa agtcatcgct caggccctga
181 aaacgcaaga tgtggagtac atatttggca tcgtaggcat cccagtgacc gaaatcgcca
241 ttgctgccca gcagctaggc atcaagtaca tcgggatgag gaatgagcaa gcggcttgtt
301 atgctgcctc cgcgattgga tatctgacaa gcaggccagg agtctgcctt gttgtttctg
361 gcccaggtct catccatgcc ttgggcggta tggcaaatgc aaacatgaac tgctggccct
421 tgcttgtgat tggtggttcc tctgaaagaa accaagaaac aatgggagct ttccaggagt
481 ttcctcaggt tgaagcttgt agattatata ccaagttctc tgcccgccca agcagcatag
541 aagctattcc ttttgttatt gaaaaggcag tgagaagcag tatctatggt cgtccaggtg
601 cttgctatgt tgacatacca gcagattttg tgaaccttca ggtgaatgtg aattctataa
661 agtacatgga acgctgcatg tcacctccta ttagcatggc agaaacctct gctgtgtgca
721 cggcggcttc tgttattagg aatgccaaac aaccccttct tatcatcggg aaaggtgctg
781 cttacgctca tgcagaagag agtatcaaga aattggtgga gcaatataaa ctgccatttt
841 tgcccacccc tatggggaag ggtgttgtcc ctgacaacca tccatactgt gtaggtgcag
901 ccagatccag ggctttgcaa tttgctgatg taattgtgtt atttggtgcc agactaaatt
961 ggattttaca ttttggactg cctccaagat atcagccaga tgtgaagttt atccaggttg
1021 atatctgtgc agaagaattg gggaataatg taaagcccgc tgttactttg ctaggaaaca
1081 tacatgctgt cactaagcag cttttagagg aacttgataa aacaccatgg cagtatcctc
1141 cagagagcaa gtggtggaaa actctgagag aaaaaatgaa gagcaatgaa gctgcatcca
1201 aggaactagc ttctaaaaaa tccctgccta tgaattatta cacagtattc taccatgttc
1261 aagaacaact acctagagac tgtttcgtgg taagtgaagg agcaaatact atggacattg
1321 gacggactgt gcttcagaac taccttcctc gtcacaggct tgatgctggt actttcggaa
1381 caatgggagt tggtttggga tttgctattg cagctgccgt ggtggctaaa gatagaagcc
1441 ctgggcaatg gatcatctgt gtggaaggag acagtgcatt tgggttttct ggcatggagg
1501 tagaaaccat ctgcaggtac aacttgccaa tcatactgtt ggtagtgaat aacaatggaa
1561 tttaccaagg ttttgataca gatacttgga aagaaatgtt aaaatttcaa gatgctactg
1621 cagtggtccc tccaatgtgt ttgctgccaa attcacatta tgagcaagtc atgactgcat
1681 ttggaggcaa agggtatttt gtacaaacac cagaagaact ccaaaaatcc ctgaggcaga
1741 gcctagcaga cacaactaaa ccttctctta tcaacatcat gattgagccc caagccacac
1801 ggaaggccca ggattttcat tggctgaccc gctctaatat gtaaataaag acgccagttg
1861 gtggtcttga gttttcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
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