LOCUS BC001605 2078 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens phosphoribosyl pyrophosphate synthetase 1, mRNA (cDNA
clone MGC:2256 IMAGE:3542584), complete cds.
ACCESSION BC001605
VERSION BC001605.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2078)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2078)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: k Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 19923737.
FEATURES Location/Qualifiers
source 1..2078
/db_xref="H-InvDB:HIT000030512"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2256 IMAGE:3542584"
/tissue_type="Lymph, Burkitt lymphoma"
/clone_lib="NIH_MGC_8"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2078
/gene="PRPS1"
/gene_synonym="PRS I"
/gene_synonym="PRSI"
/db_xref="GeneID:5631"
/db_xref="HGNC:HGNC:9462"
/db_xref="MIM:311850"
CDS 101..1057
/gene="PRPS1"
/gene_synonym="PRS I"
/gene_synonym="PRSI"
/codon_start=1
/product="phosphoribosyl pyrophosphate synthetase 1"
/protein_id="AAH01605.1"
/db_xref="GeneID:5631"
/db_xref="HGNC:HGNC:9462"
/db_xref="MIM:311850"
/translation="MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEI
GESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDK
SRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENIS
EWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAIL
VDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIP
QEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL"
BASE COUNT 540 a 449 c 505 g 584 t
ORIGIN
1 gcaacgcaaa gcgcttggta ttgagtctgt ggccgacttc ggttccggtc tctgcagcag
61 ccgtgatcgc ttagtggagt gcttagggta gttggccagg atgccgaata tcaaaatctt
121 cagcggcagc tcccaccagg acttatctca gaaaattgct gaccgcctgg gcctggagct
181 aggcaaggtg gtgactaaga aattcagcaa ccaggagacc tgtgtggaaa ttggtgaaag
241 tgtacgtgga gaggatgtct acattgttca gagtggttgt ggcgaaatca atgacaattt
301 aatggagctt ttgatcatga ttaatgcctg caagattgct tcagccagcc gggttactgc
361 agtcatccca tgcttccctt atgcccggca ggataagaaa gataagagcc gggcgccaat
421 ctcagccaag cttgttgcaa atatgctatc tgtagcaggt gcagatcata ttatcaccat
481 ggacctacat gcttctcaaa ttcagggctt ttttgatatc ccagtagaca atttgtatgc
541 agagccggct gtcctaaagt ggataaggga gaatatctct gagtggagga actgcactat
601 tgtctcacct gatgctggtg gagctaagag agtgacctcc attgcagaca ggctgaatgt
661 ggactttgcc ttgattcaca aagaacggaa gaaggccaat gaagtggacc gcatggtgct
721 tgtgggagat gtgaaggatc gggtggccat ccttgtggat gacatggctg acacttgtgg
781 cacaatctgc catgcagctg acaaacttct ctcagctggc gccaccagag tttatgccat
841 cttgactcat ggaatcttct ccggtcctgc tatttctcgc atcaacaacg catgctttga
901 ggcagtagta gtcaccaata ccatacctca ggaggacaag atgaagcatt gctccaaaat
961 acaggtgatt gacatctcta tgatccttgc agaagccatc aggagaactc acaatggaga
1021 atccgtttct tacctattca gccatgtccc tttataatag agtaacttct gaggcttttt
1081 gagaataaaa tccaccccac ccttgtttcc ccttggtatt tgatgacaaa ttcagcagaa
1141 gacccggctt gctccagtgt agctttctac atcccacatc aggtatatta gagcttatcc
1201 gaactgggga aagacggatt gagattaact gctgggacct cctacctgca ttatctcatt
1261 ctggcttcct tgataattct gtgggccttg cagctttaac tatagctcag ctgctgcaag
1321 atttcagact tttgaggatg ttgtgtgagg gtgtttgact gtgactgggg aagctcagac
1381 tactttgtat gtgaatgctt cagggttttc tttgttgaga acaactagca acaaaggcaa
1441 cccatgtgtg accagttctc cccaaggtct atgctaaatt atagcaagag ccctgggcaa
1501 ccccaaacct agtcctggta gctgagcacc ctgtaaggca ggagcaggca gctcagcttg
1561 agcagacatt gggtgggggg tggggggtgg ttgagggggg aggcagcaca gtgcagcaaa
1621 tgtttcttgg gaggaagaag cctgatccat caccatctgc ttgactatgt agcttggatt
1681 ctcctttgta cctatccctt tcgatttggc tttaccttca tctatcttga tcctttcctg
1741 gccaaatatc ctcttgggcc caaatgaaca ttgtaccata gtcttctgga aagcaaacat
1801 gcttcctgct atgtaattgc taacattcat attagatgat gtgctgtagc ttgatcttcc
1861 ttagcctact gccactgagg cagtaggttt taggtggtat cgtagtgcct tttgattaat
1921 ttaagtattt aattttcatc ttccttcttt ggatctattt ggcctctcaa atgaactgag
1981 attcctgtta aaaaagattg atgttattgt ctcttgtaga ggaaactaat aaagtgtgtg
2041 tacctgtgtg aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//