LOCUS BC001371 1903 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ER degradation enhancer, mannosidase alpha-like 2,
mRNA (cDNA clone MGC:935 IMAGE:3051376), complete cds.
ACCESSION BC001371
VERSION BC001371.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1903)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1903)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC001371.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: e Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8922666.
FEATURES Location/Qualifiers
source 1..1903
/db_xref="H-InvDB:HIT000030355"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:935 IMAGE:3051376"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_15"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1903
/gene="EDEM2"
/gene_synonym="bA4204.1"
/gene_synonym="FLJ10783"
/db_xref="GeneID:55741"
/db_xref="HGNC:HGNC:15877"
CDS 68..1804
/gene="EDEM2"
/gene_synonym="bA4204.1"
/gene_synonym="FLJ10783"
/codon_start=1
/product="ER degradation enhancer, mannosidase alpha-like
2"
/protein_id="AAH01371.1"
/db_xref="GeneID:55741"
/db_xref="HGNC:HGNC:15877"
/translation="MPFRLLIPLGLLCALLPQHHGAPGPDGSAPDPAHYRERVKAMFY
HAYDSYLENAFPFDELRPLTCDGHDTWGSFSLTLIDALDTLLILGNVSEFQRVVEVLQ
DSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARK
LLPAFQTPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVA
RVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKL
MAMFLEYNKAIRNYTRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDIDNAMR
TFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLEL
GRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNN
GSTFDTVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRLKEEQWEVEDLMREFYSL
KRSRSKFQKNTVSSGPWEPPARPGTLFSPENHDQARERKPAKQKVPLLSCPSQPFTSK
LALLGQVFLDSS"
BASE COUNT 462 a 511 c 505 g 425 t
ORIGIN
1 agctcccagg atgaactggt tgcagtggct gctgctgctg cgggggcgct gagaggacac
61 gagctctatg cctttccggc tgctcatccc gctcggcctc ctgtgcgcgc tgctgcctca
121 gcaccatggt gcgccaggtc ccgacggctc cgcgccagat cccgcccact acagggagcg
181 agtcaaggcc atgttctacc acgcctacga cagctacctg gagaatgcct ttcccttcga
241 tgagctgcga cctctcacct gtgacgggca cgacacctgg ggcagttttt ctctgactct
301 aattgatgca ctggacacct tgctgatttt ggggaatgtc tcagaattcc aaagagtggt
361 tgaagtgctc caggacagcg tggactttga tattgatgtg aacgcctctg tgtttgaaac
421 aaacattcga gtggtaggag gactcctgtc tgctcatctg ctctccaaga aggctggggt
481 ggaagtagag gctggatggc cctgttccgg gcctctcctg agaatggctg aggaggcggc
541 ccgaaaactc ctcccagcct ttcagacccc cactggcatg ccatatggaa cagtgaactt
601 acttcatggc gtgaacccag gagagacccc tgtcacctgt acggcaggga ttgggacctt
661 cattgttgaa tttgccaccc tgagcagcct cactggtgac ccggtgttcg aagatgtggc
721 cagagtggct ttgatgcgcc tctgggagag ccggtcagat atcgggctgg tcggcaacca
781 cattgatgtg ctcactggca agtgggtggc ccaggacgca ggcatcgggg ctggcgtgga
841 ctcctacttt gagtacttgg tgaaaggagc catcctgctt caggataaga agctcatggc
901 catgttccta gagtataaca aagccatccg gaactacacc cgcttcgatg actggtacct
961 gtgggttcag atgtacaagg ggactgtgtc catgccagtc ttccagtcct tggaggccta
1021 ctggcctggt cttcagagcc tcattggaga cattgacaat gccatgagga ccttcctcaa
1081 ctactacact gtatggaagc agtttggggg gctcccggaa ttctacaaca ttcctcaggg
1141 atacacagtg gagaagcgag agggctaccc acttcggcca gaacttattg aaagcgcaat
1201 gtacctctac cgtgccacgg gggatcccac cctcctagaa ctcggaagag atgctgtgga
1261 atccattgaa aaaatcagca aggtggagtg cggatttgca acaatcaaag atctgcgaga
1321 ccacaagctg gacaaccgca tggagtcgtt cttcctggcc gagactgtga aatacctcta
1381 cctcctgttt gacccaacca acttcatcca caacaatggg tccaccttcg acacggtgat
1441 caccccctat ggggagtgca tcctgggggc tggggggtac atcttcaaca cagaagctca
1501 ccccatcgac cctgccgccc tgcactgctg ccagaggctg aaggaagagc agtgggaggt
1561 ggaggacttg atgagggaat tctactctct caaacggagc aggtcgaaat ttcagaaaaa
1621 cactgttagt tcggggccat gggaacctcc agcaaggcca ggaacactct tctcaccaga
1681 aaaccatgac caggcaaggg agaggaagcc tgccaaacag aaggtcccac ttctcagctg
1741 ccccagtcag cccttcacct ccaagttggc attactggga caggttttcc tagactcctc
1801 ataaccactg gataattttt ttatttttat ttttttgagg ctaaactata ataaattgct
1861 tttggctatc ataaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
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