LOCUS BC001180 1780 bp mRNA linear HUM 22-FEB-2007
DEFINITION Homo sapiens transforming growth factor, beta 1, mRNA (cDNA clone
MGC:2323 IMAGE:3356605), complete cds.
ACCESSION BC001180
VERSION BC001180.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1780)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1780)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: e Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 63025221.
FEATURES Location/Qualifiers
source 1..1780
/db_xref="H-InvDB:HIT000030201"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2323 IMAGE:3356605"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1780
/gene="TGFB1"
/gene_synonym="CED"
/db_xref="GeneID:7040"
/db_xref="HGNC:HGNC:11766"
/db_xref="MIM:190180"
CDS 447..1619
/gene="TGFB1"
/gene_synonym="CED"
/codon_start=1
/product="transforming growth factor, beta 1"
/protein_id="AAH01180.1"
/db_xref="GeneID:7040"
/db_xref="HGNC:HGNC:11766"
/db_xref="MIM:190180"
/translation="MPPSGLRLLLLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRK
RIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEAD
YYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRL
KLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFR
LSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRH
RRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDT
QYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS"
BASE COUNT 341 a 648 c 493 g 298 t
ORIGIN
1 acacggcgtc cctcaggcgc ccccattccg gaccagccct cgggagtcgc cgacccggcc
61 tcccgcaaag acttttcccc agacctcggg cgcaccccct gcacgccgcc ttcatccccg
121 gcctgtctcc tgagcccccg cgcatcctag accctttctc ctccaggaga cggatctctc
181 tccgacctgc cacagatccc ctattcaaga ccacccacct tctggtacca gatcgcgccc
241 atctaggtta tttccgtggg atactgagac acccccggtc caagcctccc ctccaccact
301 gcgcccttct ccctgaggac ctcagctttc cctcgaggcc ctcctacctt ttgccgggag
361 acccccagcc cctgcagggg cggggcctcc ccaccacacc agccctgttc gcgctctcgg
421 cagtgccggg gggcgccgcc tcccccatgc cgccctccgg gctgcggctg ctgctgctgc
481 tgctaccgct gctgtggcta ctggtgctga cgcctggccg gccggccgcg ggactatcca
541 cctgcaagac tatcgacatg gagctggtga agcggaagcg catcgaggcc atccgcggcc
601 agatcctgtc caagctgcgg ctcgccagcc ccccgagcca gggggaggtg ccgcccggcc
661 cgctgcccga ggccgtgctc gccctgtaca acagcacccg cgaccgggtg gccggggaga
721 gtgcagaacc ggagcccgag cctgaggccg actactacgc caaggaggtc acccgcgtgc
781 taatggtgga aacccacaac gaaatctatg acaagttcaa gcagagtaca cacagcatat
841 atatgttctt caacacatca gagctccgag aagcggtacc tgaacccgtg ttgctctccc
901 gggcagagct gcgtctgctg aggctcaagt taaaagtgga gcagcacgtg gagctgtacc
961 agaaatacag caacaattcc tggcgatacc tcagcaaccg gctgctggca cccagcgact
1021 cgccagagtg gttatctttt gatgtcaccg gagttgtgcg gcagtggttg agccgtggag
1081 gggaaattga gggctttcgc cttagcgccc actgctcctg tgacagcagg gataacacac
1141 tgcaagtgga catcaacggg ttcactaccg gccgccgagg tgacctggcc accattcatg
1201 gcatgaaccg gcctttcctg cttctcatgg ccaccccgct ggagagggcc cagcatctgc
1261 aaagctcccg gcaccgccga gccctggaca ccaactattg cttcagctcc acggagaaga
1321 actgctgcgt gcggcagctg tacattgact tccgcaagga cctcggctgg aagtggatcc
1381 acgagcccaa gggctaccat gccaacttct gcctcgggcc ctgcccctac atttggagcc
1441 tggacacgca gtacagcaag gtcctggccc tgtacaacca gcataacccg ggcgcctcgg
1501 cggcgccgtg ctgcgtgccg caggcgctgg agccgctgcc catcgtgtac tacgtgggcc
1561 gcaagcccaa ggtggagcag ctgtccaaca tgatcgtgcg ctcctgcaag tgcagctgag
1621 gtcccgcccc gccccgcccc gccccggcag gcccggcccc accccgcccc gcccccgctg
1681 ccttgcccat gggggctgta tttaaggaca cccgtgccca agcccacctg gggccccatt
1741 aaagatggag agaggactgc gaaaaaaaaa aaaaaaaaaa
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