LOCUS       BC000742                 863 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens glutathione peroxidase 1, mRNA (cDNA clone MGC:2335
            IMAGE:3505654), complete cds.
ACCESSION   BC000742
VERSION     BC000742.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-NOV-2000) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Aug 19, 2003 this sequence version replaced BC000742.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 7 Row: d Column: 11
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 41406081.
FEATURES             Location/Qualifiers
     source          1..863
                     /db_xref="H-InvDB:HIT000029886"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:2335 IMAGE:3505654"
                     /tissue_type="Placenta, choriocarcinoma"
                     /clone_lib="NIH_MGC_21"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..863
                     /gene="GPX1"
                     /gene_synonym="GSHPX1"
                     /gene_synonym="MGC14399"
                     /db_xref="GeneID:2876"
                     /db_xref="HGNC:HGNC:4553"
                     /db_xref="MIM:138320"
     CDS             24..635
                     /gene="GPX1"
                     /gene_synonym="GSHPX1"
                     /gene_synonym="MGC14399"
                     /codon_start=1
                     /transl_except=(pos:168..170,aa:Sec)
                     /product="glutathione peroxidase 1"
                     /protein_id="AAH00742.3"
                     /db_xref="GeneID:2876"
                     /db_xref="HGNC:HGNC:4553"
                     /db_xref="MIM:138320"
                     /translation="MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIEN
                     VASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPG
                     GGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDV
                     AWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA"
BASE COUNT          162 a          264 c          262 g          175 t
ORIGIN      
        1 ctggcttctt ggacaattgc gccatgtgtg ctgctcggct agcggcggcg gcggcggcgg
       61 cccagtcggt gtatgccttc tcggcgcgcc cgctggccgg cggggagcct gtgagcctgg
      121 gctccctgcg gggcaaggta ctacttatcg agaatgtggc gtccctctga ggcaccacgg
      181 tccgggacta cacccagatg aacgagctgc agcggcgcct cggaccccgg ggcctggtgg
      241 tgctcggctt cccgtgcaac cagtttgggc atcaggagaa cgccaagaac gaagagattc
      301 tgaattccct caagtacgtc cggcctggtg gtgggttcga gcccaacttc atgctcttcg
      361 agaagtgcga ggtgaacggt gcgggggcgc accctctctt cgccttcctg cgggaggccc
      421 tgccagctcc cagcgacgac gccaccgcgc ttatgaccga ccccaagctc atcacctggt
      481 ctccggtgtg tcgcaacgat gttgcctgga actttgagaa gttcctggtg ggccctgacg
      541 gtgtgcccct acgcaggtac agccgccgct tccagaccat tgacatcgag cctgacatcg
      601 aagccctgct gtctcaaggg cccagctgtg cctagggcgc ccctcctacc ccggctgctt
      661 ggcagttgca gtgctgctgt ctcggggggg ttttcatcta tgagggtgtt tcctctaaac
      721 ctacgaggga ggaacacctg atcttacaga aaataccacc tcgagatggg tgctggtcct
      781 gttgatccca gtctctgcca gaccaaggcg agtttcccca ctaataaagt gccgggtgtc
      841 agcaaaaaaa aaaaaaaaaa aaa
//