LOCUS BC000730 3452 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens calpain 6, mRNA (cDNA clone MGC:1883 IMAGE:3503916),
complete cds.
ACCESSION BC000730
VERSION BC000730.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3452)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3452)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC000730.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: c Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13186315.
FEATURES Location/Qualifiers
source 1..3452
/db_xref="H-InvDB:HIT000029875"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1883 IMAGE:3503916"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3452
/gene="CAPN6"
/gene_synonym="CalpM"
/gene_synonym="CANPX"
/gene_synonym="CAPNX"
/gene_synonym="DJ914P14.1"
/db_xref="GeneID:827"
/db_xref="HGNC:HGNC:1483"
/db_xref="MIM:300146"
CDS 21..1946
/gene="CAPN6"
/gene_synonym="CalpM"
/gene_synonym="CANPX"
/gene_synonym="CAPNX"
/gene_synonym="DJ914P14.1"
/codon_start=1
/product="calpain 6"
/protein_id="AAH00730.1"
/db_xref="GeneID:827"
/db_xref="HGNC:HGNC:1483"
/db_xref="MIM:300146"
/translation="MGPPLKLFKNQKYQELKQECIKDSRLFCDPTFLPENDSLFYNRL
LPGKVVWKRPQDICDDPHLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQESHWTKTIP
NHKEQEWDPQKTEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWN
ALLEKAYAKLLGCYEALDGLTITDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGEL
YKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGERLVEVFSAEK
VYMVRLRNPLGRQEWSGPWSEISEEWQQLTASDRKNLGLVMSDDGEFWMSLEDFCRNF
HKLNVCRNVNNPIFGRKELESVLGCWTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTVP
EDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRKFRLHHLYIQERAGTSTY
IDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWN
LARGYPKVVTQITVHSAEDLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQ
AIFYRRTTDIPIIVQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVK
QGHISFKVISSDDLTEL"
BASE COUNT 959 a 874 c 756 g 863 t
ORIGIN
1 ctcaggcata gttcaacact atgggtcctc ctctgaagct cttcaaaaac cagaaatacc
61 aggaactgaa gcaggaatgc atcaaagaca gcagactttt ctgtgatcca acatttctgc
121 ctgagaatga ttctcttttc tacaaccgac tgcttcctgg aaaggtggtg tggaaacgtc
181 cccaggacat ctgtgatgac ccccatctga ttgtgggcaa cattagcaac caccagctga
241 cccaagggag actggggcac aagccaatgg tttctgcatt ttcctgtttg gctgttcagg
301 agtctcattg gacaaagaca attcccaacc ataaggaaca ggaatgggac cctcaaaaaa
361 cagaaaaata cgctgggata tttcactttc gtttctggca ttttggagaa tggactgaag
421 tggtgattga tgacttgttg cccaccatta acggagatct ggtcttctct ttctccactt
481 ccatgaatga gttttggaat gctctgctgg aaaaagctta tgcaaagctg ctaggctgtt
541 atgaggccct ggatggtttg accatcactg atattattgt ggacttcacg ggcacattgg
601 ctgaaactgt tgacatgcag aaaggaagat acactgagct tgttgaggag aagtacaagc
661 tattcggaga actgtacaaa acatttacca aaggtggtct gatctgctgt tccattgagt
721 ctcccaatca ggaggagcaa gaagttgaaa ctgattgggg tctgctgaag ggccatacct
781 ataccatgac tgatattcgc aaaattcgtc ttggagagag acttgtggaa gtcttcagtg
841 ctgagaaggt gtatatggtt cgcctgagaa accccttggg aagacaggaa tggagtggcc
901 cctggagtga aatttctgaa gagtggcagc aactgactgc atcagatcgc aagaacctgg
961 ggcttgttat gtctgatgat ggagagtttt ggatgagctt ggaggacttt tgccgcaact
1021 ttcacaaact gaatgtctgc cgcaatgtga acaaccctat ttttggccga aaggagctgg
1081 aatcggtgtt gggatgctgg actgtggatg atgatcccct gatgaaccgc tcaggaggct
1141 gctataacaa ccgtgatacc ttcctgcaga atccccagta catcttcact gtgcctgagg
1201 atgggcacaa ggtcattatg tcactgcagc agaaggacct gcgcacttac cgccgaatgg
1261 gaagacctga caattacatc attggctttg agctcttcaa ggtggagatg aaccgcaaat
1321 tccgcctcca ccacctctac atccaggagc gtgctgggac ttccacctat attgacaccc
1381 gcacagtgtt tctgagcaag tacctgaaga agggcaacta tgtgcttgtc ccaaccatgt
1441 tccagcatgg tcgcaccagc gagtttctcc tgagaatctt ctctgaagtg cctgtccagc
1501 tcagggaact gactctggac atgcccaaaa tgtcctgctg gaacctggct cgtggctacc
1561 cgaaagtagt tactcagatc actgttcaca gtgctgagga cctggagaag aagtatgcca
1621 atgaaactgt aaacccatat ttggtcatca aatgtggaaa ggaggaagtc cgttctcctg
1681 tccagaagaa tacagttcat gccatttttg acacccaggc cattttctac agaaggacca
1741 ctgacattcc tattatagta caggtctgga acagccgaaa attctgtgat cagttcttgg
1801 ggcaggttac tctggatgct gaccccagcg actgccgtga tctgaagtct ctgtacctgc
1861 gtaagaaggg tggtccaact gccaaagtca agcaaggcca catcagcttc aaggttattt
1921 ccagcgatga tctcactgag ctctaaatct gcaatcccag agaatcctga caaagcgtgc
1981 caccctttta ttttccgtca ggtgccaggt cttagttaag attcacaatc tttagaaaga
2041 atgagattca caataattaa ctcttcctct cttctgataa attccccata cctcccaatc
2101 caagtagcat ctgtagctac ataacctata tacctccagc agctggacat ggggaggcga
2161 cagtcctatc tagacatcat acacatttgc caagaaagga tctctggggc ttccgggggt
2221 gagattcaag caggacaata acaagaggct ggacacccta cagatgtctt tgatgttttc
2281 agttgtttga tatatctccc ctgtagggca tgttgaggaa ggaggagggc tgatcaaggc
2341 caagctggtc tagcctgaca tcctagctcc tgactgaaca ctatagactt cccagcagca
2401 tttcacccag cagccagagc cggctttaag tccccaaccc ttacagacac cactgccacc
2461 accaccaacc acgaccacca ccaccaccac cactcaccac catcatcacc tccggaaagt
2521 gtagtcctgc cctaacccaa gtcacccccg acagtaaatt ttaccttcat gttgagaaag
2581 cttcctggtg cttaatcaag agctggagtt caatgagtcc tagacagtga gaggggcctg
2641 agcttcagct caatggaagc ctgctgtgtg ccacaagacg gaaaagtgga agaagctgca
2701 gtgggagaca aagcctcggt cccccaccca tccacacaca cctacactca cacacgcgca
2761 catgggcgcg cacgaactac cattcaggca gtcagtgggc aagaggaaag ataagtaagt
2821 accatacaca cctaaaagat gagagaattc atccagacat attacagcca gtttggggcc
2881 cctgactgca atgtgaaacc tctcgctgct gctaggttta caaacaagcc cattgtcctg
2941 tgcctcctaa tatcatttgt actgaagacc ccatctgggg acttgagact ttggtcccag
3001 cccagactcc tcagactttt ctctcagttg ggatgcttca ctcgctgggg gtgtttgttt
3061 gccctctcat ttttcagtac ttctacagaa ttttctctag agtcagtcat tatgaaatgt
3121 acttccctcc atcttaacct atcaactttc tgcccctcct tcaaggccca gtataaatgc
3181 cacctcctcc atgaagcctt ccctaattcc accccaaacc cccaccttca acaatatttc
3241 aacgcttctg caatgatgaa aaagaaacat agttgtagta cttagcctac ctagaccagc
3301 aagcattcat ttttagctcg ctcatttttt accatgtttt ccagtctgtt taacttctgc
3361 agtgccttca ctacactgcc ttacataaac caaatcacaa taaagttcat attcagtaaa
3421 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
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