LOCUS BC000671 1703 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens claudin 4, mRNA (cDNA clone MGC:1778 IMAGE:3349211),
complete cds.
ACCESSION BC000671
VERSION BC000671.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1703)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1703)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000671.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: f Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34335232.
FEATURES Location/Qualifiers
source 1..1703
/db_xref="H-InvDB:HIT000029824"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1778 IMAGE:3349211"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_15"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1703
/gene="CLDN4"
/gene_synonym="CPE-R"
/gene_synonym="CPER"
/gene_synonym="hCPE-R"
/gene_synonym="WBSCR8"
/db_xref="GeneID:1364"
/db_xref="HGNC:HGNC:2046"
/db_xref="MIM:602909"
CDS 197..826
/gene="CLDN4"
/gene_synonym="CPE-R"
/gene_synonym="CPER"
/gene_synonym="hCPE-R"
/gene_synonym="WBSCR8"
/codon_start=1
/product="claudin 4"
/protein_id="AAH00671.1"
/db_xref="GeneID:1364"
/db_xref="HGNC:HGNC:2046"
/db_xref="MIM:602909"
/translation="MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQ
TIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGG
KCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREM
GASLYVGWAASGLLLLGGGLLCCNCPPRTDKPYSAKYSAARSAAASNYV"
BASE COUNT 306 a 501 c 522 g 374 t
ORIGIN
1 ggcagctgtc ggctggaagg aactggtctg ctcacacttg ctggcttgcg catcaggact
61 ggctttatct cctgactcac ggtgcaaagg tgcactctgc gaacgttaag tccgtcccca
121 gcgcttggaa tcctacggcc cccacagccg gatcccctca gccttccagg tcctcaactc
181 ccgcggacgc tgaacaatgg cctccatggg gctacaggta atgggcatcg cgctggccgt
241 cctgggctgg ctggccgtca tgctgtgctg cgcgctgccc atgtggcgcg tgacggcctt
301 catcggcagc aacattgtca cctcgcagac catctgggag ggcctatgga tgaactgcgt
361 ggtgcagagc accggccaga tgcagtgcaa ggtgtacgac tcgctgctgg cactgccgca
421 ggacctgcag gcggcccgcg ccctcgtcat catcagcatc atcgtggctg ctctgggcgt
481 gctgctgtcc gtggtggggg gcaagtgtac caactgcctg gaggatgaaa gcgccaaggc
541 caagaccatg atcgtggcgg gcgtggtgtt cctgttggcc ggccttatgg tgatagtgcc
601 ggtgtcctgg acggcccaca acatcatcca agacttctac aatccgctgg tggcctccgg
661 gcagaagcgg gagatgggtg cctcgctcta cgtcggctgg gccgcctccg gcctgctgct
721 ccttggcggg gggctgcttt gctgcaactg tccaccccgc acagacaagc cttactccgc
781 caagtattct gctgcccgct ctgctgctgc cagcaactac gtgtaaggtg ccacggctcc
841 actctgttcc tctctgcttt gttcttccct ggactgagct cagcgcaggc tgtgacccca
901 ggagggccct gccacgggcc actggctgct ggggactggg gactgggcag agactgagcc
961 aggcaggaag gcagcagcct tcagcctctc tggcccactc ggacaacttc ccaaggccgc
1021 ctcctgctag caagaacaga gtccaccctc ctctggatat tggggaggga cggaagtgac
1081 agggtgtggt ggtggagtgg ggagctggct tctgctggcc aggatggctt aaccctgact
1141 ttgggatctg cctgcatcgg tgttggccac tgtccccatt tacattttcc ccactctgtc
1201 tgcctgcatc tcctctgttg cgggtaggcc ttgatatcac ctctgggact gtgccttgct
1261 caccgaaacc cgcgcccagg agtatggctg aggccttgcc cacccacctg cctgggaagt
1321 gcagagtgga tggacgggtt tagaggggag gggcgaaggt gctgtaaaca ggtttgggca
1381 gtggtggggg agggggccag agaggcggct caggttgccc agctctgtgg cctcaggact
1441 ctctgcctca cccgcttcag cccagggccc ctggagactg atcccctctg agtcctctgc
1501 cccttccaag gacactaatg agcctgggag ggtggcaggg aggaggggac agcttcaccc
1561 ttggaagtcc tggggttttt cctcttcctt ctttgtggtt tctgttttgt aatttaagaa
1621 gagctattca tcactgtaat tattattatt ttctacaata aatgggacct gtgcacagga
1681 aaaaaaaaaa aaaaaaaaaa aaa
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