LOCUS BC000657 1608 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens 8-oxoguanine DNA glycosylase, mRNA (cDNA clone
MGC:1841 IMAGE:3350168), complete cds.
ACCESSION BC000657
VERSION BC000657.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1608)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1608)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000657.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: b Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8670533.
FEATURES Location/Qualifiers
source 1..1608
/db_xref="H-InvDB:HIT000029812"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1841 IMAGE:3350168"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1608
/gene="OGG1"
/gene_synonym="HMMH"
/gene_synonym="HOGG1"
/gene_synonym="MUTM"
/gene_synonym="OGH1"
/db_xref="GeneID:4968"
/db_xref="HGNC:HGNC:8125"
/db_xref="MIM:601982"
CDS 298..1335
/gene="OGG1"
/gene_synonym="HMMH"
/gene_synonym="HOGG1"
/gene_synonym="MUTM"
/gene_synonym="OGH1"
/codon_start=1
/product="8-oxoguanine DNA glycosylase"
/protein_id="AAH00657.1"
/db_xref="GeneID:4968"
/db_xref="HGNC:HGNC:8125"
/db_xref="MIM:601982"
/translation="MPARALLPRRMGHRTLASTPALWASIPCPRSELRLDLVLPSGQS
FRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDELEAVRKYFQL
DVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVE
RLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARYVSASARAILEE
QGGLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQ
RDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLRQCRHAQEPPA
KRRKGSKGPEG"
BASE COUNT 357 a 460 c 482 g 309 t
ORIGIN
1 cacagctgtg cgcgcccaca ggctctgggg gcgggagaag ataagtcgca aggagggggc
61 gggacctaca cctcaggaaa gccggagaat tggggcacga agcggggctt tgatgacccg
121 caaagggcga ggcatgcagg aggtggagga attaagtgaa acagggaagg ttgttaaaca
181 gcaccgtgtg ggcgaggcct taagggtcgt ggtccttgtc tgggcggggt ctttgggcgt
241 cgacgaggcc tggttctggg taggcggggc tactacgggg cggtgcctgc tgtggaaatg
301 cctgcccgcg cgcttctgcc caggcgcatg gggcatcgta ctctagcctc cactcctgcc
361 ctgtgggcct ccatcccgtg ccctcgctct gagctgcgcc tggacctggt tctgccttct
421 ggacaatctt tccggtggag ggagcaaagt cctgcacact ggagtggtgt actagcggat
481 caagtatgga cactgactca gactgaggag cagctccact gcactgtgta ccgaggagac
541 aagagccagg ctagcaggcc cacaccagac gagctggagg ccgtgcgcaa gtacttccag
601 ctagatgtta ccctggctca actgtatcac cactggggtt ccgtggactc ccacttccaa
661 gaggtggctc agaaattcca aggtgtgcga ctgctgcgac aagaccccat cgaatgcctt
721 ttctctttta tctgttcctc caacaacaac atcgcccgca tcactggcat ggtggagcgg
781 ctgtgccagg cttttggacc tcggctcatc cagcttgatg atgtcaccta ccatggcttc
841 cccagcctgc aggccctggc tgggccagag gtggaggctc atctcaggaa gctgggcctg
901 ggctatcgtg cccgttacgt gagtgccagt gcccgagcca tcctggaaga acagggcggg
961 ctagcctggc tgcagcagct acgagagtcc tcatatgagg aggcccacaa ggccctctgc
1021 atcctgcctg gagtgggcac caaggtggct gactgcatct gcctgatggc cctagacaag
1081 ccccaggctg tgcccgtgga tgtccatatg tggcacattg cccaacgtga ctacagctgg
1141 caccctacca cgtcccaggc gaagggaccg agcccccaga ccaacaagga actgggaaac
1201 tttttccgga gcctgtgggg accttatgct ggctgggccc aagcggtgct gttcagtgcc
1261 gacctgcgcc aatgccgcca tgctcaggag ccaccagcaa agcgcagaaa gggttccaaa
1321 gggccggaag gctagatggg gcaccctgga caaagaaatt ccccaagcac cttcccctcc
1381 attccccact tctctctccc catccccacc cagtctcatg ttggggaggg gcctccctgt
1441 gactacctca aaggccaggc acccccaaat caagcagtca gtttgcacaa caagatgggg
1501 tgggggatat tgagggagac agcgctaagg atggttttat cttcccttta ttacaagaag
1561 gaacaataaa atagaaacat ttgtatggaa aaaaaaaaaa aaaaaaaa
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