LOCUS BC000622 1895 bp mRNA linear HUM 19-NOV-2003
DEFINITION Homo sapiens WD repeat and HMG-box DNA binding protein 1, mRNA
(cDNA clone IMAGE:3346434), partial cds.
ACCESSION BC000622
VERSION BC000622.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1895)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1895)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000622.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: o Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 5901891.
FEATURES Location/Qualifiers
source 1..1895
/db_xref="H-InvDB:HIT000085852"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3346434"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>1895
/gene="WDHD1"
/gene_synonym="AND-1"
/db_xref="GeneID:11169"
/db_xref="MIM:608126"
CDS 56..>1895
/gene="WDHD1"
/gene_synonym="AND-1"
/codon_start=1
/product="WDHD1 protein"
/protein_id="AAH00622.1"
/db_xref="GeneID:11169"
/db_xref="MIM:608126"
/translation="MPATRKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRIWEDLD
DDDPKFINVGEKAYSCALKSGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVVF
NGDGTKIAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSV
RVWQISDQTCAISWPLLQKCNDVINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRESW
SHQFDLSDNFISQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMERVKHEKGYAI
CGLAWHPTCGRISYTDAEGNLGLLENVCDPSGKTSSSKVSSRVEKDYNDLFDGDDMSN
AGDFLNDNAVEIPSFSKGIINDDEDDEDLMMASGRPRQRSHILEDDENSVDISMLKTG
SSLLKEEEEDGQEGSIHNLPLVTSQRPFYDGPMPTPRQKPFQSGSTPLHLTHRFMVWN
SIGIIRCYNDEQDNAIDVEFHDTSIHHATHLSNTLNYTIADLSHEAILLACESTDELA
SKLHCLHFSSWDSSKEWIIDLPQNEDIEAICLGQGWAAAATSALLLRLFTIGGVQKEV
FSLAGPVVSMAGHGEQLFIVYHRGTGFDGDQCLGVQLLELGKKKKKK"
misc_feature 83..919
/gene="WDHD1"
/gene_synonym="AND-1"
/note="WD40; Region: WD40 domain, found in a number of
eukaryotic proteins that cover a wide variety of functions
including adaptor/regulatory modules in signal
transduction, pre-mRNA processing and cytoskeleton
assembly"
/db_xref="CDD:cd00200"
BASE COUNT 565 a 338 c 457 g 535 t
ORIGIN
1 ctcttgtgga tcctcagtgg cggaggctcg gtcacccgga taggtaaagg aaaacatgcc
61 tgccacacgg aagccaatga gatatgggca tacagaggga cacacggagg tctgttttga
121 tgattctggg agttttattg tgacttgtgg aagtgatggt gatgtgagga tttgggaaga
181 cttggatgat gatgatccta agttcattaa tgttggagaa aaggcatatt catgtgcttt
241 gaagagtgga aaactggtca ctgcagtttc taataatact attcaagtcc acacatttcc
301 tgaaggagtt ccagatggta tattgactcg cttcactaca aatgcaaacc atgtggtctt
361 taatggggat ggtactaaaa ttgctgctgg atctagtgat tttctagtca aaattgtgga
421 tgtgatggat agcagccaac agaaaacatt tcgaggacat gatgcccctg ttttaagtct
481 ttcctttgat cctaaggaca tctttctggc atcagctagt tgtgatggat ctgtcagagt
541 gtggcaaatt tcagatcaga catgtgctat tagttggcca ctgctacaaa aatgcaacga
601 tgtgataaat gcaaaatcaa tctgcagact tgcttggcag ccaaaaagtg ggaagttact
661 ggcaattcct gtggaaaaat ctgttaagct atatagaaga gaatcttgga gtcatcaatt
721 tgatctttca gataatttca tctctcagac cctcaatata gtaacctggt ctccctgtgg
781 gcaatattta gctgcaggta gtattaatgg tctaatcata gtttggaatg tggaaaccaa
841 agactgcatg gaaagggtga aacatgagaa aggttatgca atttgtggtc tggcatggca
901 tcctacttgt ggtcgaatat cgtatactga tgcggaagga aatctagggc ttctagagaa
961 tgtttgtgac cccagtggaa agacatcaag cagtaaggta tctagcagag tggaaaagga
1021 ttataatgat ctttttgatg gagatgatat gagtaatgct ggtgattttc taaatgacaa
1081 tgcagttgag atcccttctt tttcaaaagg gattataaat gatgatgagg atgatgaaga
1141 cctcatgatg gcttcaggtc gtcctagaca gcgaagtcac atcctagaag atgatgaaaa
1201 ctcagttgat atttcaatgc taaaaactgg ttctagtctt ctcaaagagg aggaggaaga
1261 tggtcaagaa ggcagcattc acaatctacc acttgtaaca tcccaaaggc cattttatga
1321 tggacccatg ccaactcccc ggcaaaagcc atttcagtca ggttctacac cgttgcatct
1381 cactcacaga ttcatggtgt ggaactctat tggaattatt cgctgctata atgatgagca
1441 agacaatgcc atagatgtgg agttccatga tacctccata caccatgcaa cacacttatc
1501 aaacactttg aattatacaa tagcagatct ttcccacgaa gctattttgt tggcatgtga
1561 aagcactgat gaactagcaa gcaagcttca ctgcctgcac tttagttctt gggattcaag
1621 caaagagtgg ataatagact tgcctcagaa tgaggatatt gaagccatat gtctcggtca
1681 aggatgggct gctgccgcta ctagtgccct gcttcttcga ttgtttacta ttggaggggt
1741 tcaaaaagag gtattcagcc ttgctggacc tgtggtgtca atggcaggac atggagaaca
1801 gcttttcatt gtttatcaca gaggtacagg atttgatggg gatcagtgcc ttggagttca
1861 actgctagag ctggggaaaa aaaaaaaaaa aaaaa
//