LOCUS BC000605 1236 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens glyoxylate reductase/hydroxypyruvate reductase, mRNA
(cDNA clone MGC:3078 IMAGE:3347232), complete cds.
ACCESSION BC000605
VERSION BC000605.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1236)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1236)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 28, 2003 this sequence version replaced BC000605.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: e Column: 24.
FEATURES Location/Qualifiers
source 1..1236
/db_xref="H-InvDB:HIT000029768"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3078 IMAGE:3347232"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1236
/gene="GRHPR"
/gene_synonym="PH2"
/db_xref="GeneID:9380"
/db_xref="HGNC:HGNC:4570"
/db_xref="MIM:604296"
CDS 21..1007
/gene="GRHPR"
/gene_synonym="PH2"
/codon_start=1
/product="glyoxylate reductase/hydroxypyruvate reductase"
/protein_id="AAH00605.1"
/db_xref="GeneID:9380"
/db_xref="HGNC:HGNC:4570"
/db_xref="MIM:604296"
/translation="MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKE
LERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGY
TPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIG
LGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSL
TPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPL
PTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL"
BASE COUNT 297 a 334 c 358 g 247 t
ORIGIN
1 ggtcggcggc tgcactgcgg atgagaccgg tgcgactcat gaaggtgttc gtcacccgca
61 ggatacccgc cgagggtagg gtcgcgctcg cccgggcggc agactgtgag gtggagcagt
121 gggactcgga tgagcccatc cctgccaagg agctagagcg aggtgtggcg ggggcccacg
181 gcctgctctg cctcctctcc gaccacgtgg acaagaggat cctggatgct gcaggggcca
241 atctcaaagt catcagcacc atgtctgtgg gcatcgacca cttggctttg gatgaaatca
301 agaagcgtgg gatccgagtt ggctacaccc cagatgtcct gacagatacc accgccgaac
361 tcgcagtctc cctgctactt accacctgcc gccggttgcc ggaggccatc gaggaagtga
421 agaatggtgg ctggacctcg tggaagcccc tctggctgtg tggctatgga ctcacgcaga
481 gcactgtcgg catcatcggg ctggggcgca taggccaggc cattgctcgg cgtctgaaac
541 cattcggtgt ccagagattt ctgtacacag ggcgccagcc caggcctgag gaagcagcgg
601 aattccaggc agagtttgtg tctacccctg agctggctgc ccaatctgat ttcatcgtcg
661 tggcctgctc cttaacacct gcaaccgagg gactctgcaa caaggacttc ttccagaaga
721 tgaaggaaac agctgtgttc atcaacatca gcaggggcga cgtcgtaaac caggacgacc
781 tgtaccaggc cttggccagt ggtaagattg cagctgctgg actggatgtg acgagcccag
841 aaccactgcc tacaaaccac cctctcctga ccctgaagaa ctgtgtgatt ctgccccaca
901 ttggcagtgc cacccacaga acccgcaaca ccatgtcctt gttggcagct aacaacttgc
961 tggctggcct gagaggggag ccgatgccta gtgaactcaa gctgtagcca aacagtagag
1021 atggagggcc gggaagcaaa ccgtgccctg gtattgtcag acacacccag gcttgatttg
1081 gatccacagg cagagccaag ggaaggtgtg attctctgag gaaagagtga ttctgatata
1141 tgtacttgtc acattggtgt tggacacatt tgcgccaaaa gtatggtaat tctattatta
1201 aataattctc tgagaaaaaa aaaaaaaaaa aaaaaa
//