LOCUS BC000598 2097 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cyclin-dependent kinase inhibitor 2C (p18, inhibits
CDK4), mRNA (cDNA clone MGC:1987 IMAGE:3347370), complete cds.
ACCESSION BC000598
VERSION BC000598.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2097)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2097)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: c Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 17981697.
FEATURES Location/Qualifiers
source 1..2097
/db_xref="H-InvDB:HIT000258876"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1987 IMAGE:3347370"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2097
/gene="CDKN2C"
/gene_synonym="INK4C"
/gene_synonym="p18"
/gene_synonym="p18-INK4C"
/db_xref="GeneID:1031"
/db_xref="HGNC:HGNC:1789"
/db_xref="MIM:603369"
CDS 1208..1714
/gene="CDKN2C"
/gene_synonym="INK4C"
/gene_synonym="p18"
/gene_synonym="p18-INK4C"
/codon_start=1
/product="cyclin-dependent kinase inhibitor 2C (p18,
inhibits CDK4)"
/protein_id="AAH00598.1"
/db_xref="GeneID:1031"
/db_xref="HGNC:HGNC:1789"
/db_xref="MIM:603369"
/translation="MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV
MKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE
GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG
AGGATNLQ"
BASE COUNT 516 a 555 c 600 g 426 t
ORIGIN
1 ggcacgagga aactctgccg ttaaaatggg ggcgggtttt tcaactcaaa aagcgctcaa
61 tttttttctt ttcaaaaaaa gctgatgagg tcggaaaaaa gggagaagaa accggcaccc
121 tctctgagag gcaacagaag cagcaattgt ttcagcgaaa aaagcagcaa gggagggagt
181 gaaggaaaaa agcaaaaaag ggggcgacac gcaagtgcct gtaggggtga aaggagcagg
241 gaccggcgat ctaggggggg atcagctaca aaagaaactg tcactgggag cggtgcggcc
301 aaggaggaag cagtgctgcc aggctctgct ccagggcaca gctggctggc ggctgccctg
361 tccgcagcaa aggggcacag gccggggacc gcgagaggtg gcaaagtggc accgggcgcc
421 gaggctgctg agcgctcgcc gagacggcga ccggactggc tgccccggaa ctgcggcgac
481 tctccctact cagaacttgg cctacgtttc ccaggactct ccccatctcc agaggccccc
541 acaaaaccgg gaaaggaagg aaaggacagc ggcggcagca gctcaatgag tgcctacagc
601 agaaagcctg aacgagctcg gtcgtaggcg ggaagttccc gggggggctg cccagtgcag
661 ccgcaatgct gccgcgagct gccccagcag tccgggctcc gtagacgctt tccgcatcac
721 tctccttcct cgggctgccg ggagtcccgg gacctggcgg ggccggcatg acgggcttct
781 cgggggcccg ccgcacgccc ggcagcctcc ggagacgcgc gccgagcccg gctcccacgg
841 cctctgaggc tcggcggggc tgcggctgcc tggcgggcgg gctccggagc tttcctgagc
901 ggcattagcc cacggcttgg cccggacgcg accaaaggct cttctggaga agcccagagc
961 actgggcaat cgttacgacc tgtaacttga gggccaccga actgctactc ccgttcgcct
1021 ttggcgatca tcttttaacc ctccggagca cgtcagcatc cagccaccgc ggcgctctcc
1081 cagcagcgga ggacccagga ctatcccttc ggcgagacgg atggaaaccg agccccctgg
1141 aggacctgcc cctgcagttc tgcctcacac ggctcaagtc accaccgtga acaagggacc
1201 ctaaagaatg gccgagcctt gggggaacga gttggcgtcc gcagctgcca ggggggacct
1261 agagcaactt actagtttgt tgcaaaataa tgtaaacgtc aatgcacaaa atggatttgg
1321 aaggactgcg ctgcaggtta tgaaacttgg aaatcccgag attgccagga gactgctact
1381 tagaggtgct aatcccgatt tgaaagaccg aactggtttc gctgtcattc atgatgcggc
1441 cagagcaggt ttcctggaca ctttacagac tttgctggag tttcaagctg atgttaacat
1501 cgaggataat gaagggaacc tgcccttgca cttggctgcc aaagaaggcc acctccgggt
1561 ggtggagttc ctggtgaagc acacggccag caatgtgggg catcggaacc ataaggggga
1621 caccgcctgt gatttggcca ggctctatgg gaggaatgag gttgttagcc tgatgcaggc
1681 aaacggggct gggggagcca caaatcttca ataaacgtgg ggagggctcc cccacgttgc
1741 ctctacttta tcaattaact gagtagctct cctgactttt aatgtcattt gttaaaatac
1801 agttctgtca tatgttaagc agctaaattt tctgaaactg cataagtgaa aatcttacaa
1861 caggcttatg aatatattta agcaacatct ttttaacctg caaaatctgt tctaacatgt
1921 aattgcagat aactttgact ttcttctgaa tattttatct ttccttggct tttcccttgc
1981 ttcccctttt gccaatctca acacccaagt tgaagacttt gtttttaaaa tggtttgtcc
2041 tgatgctttt gtctaattaa aacactttca aaacaggaaa aaaaaaaaaa aaaaaaa
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