LOCUS BC000580 1241 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens prolyl 4-hydroxylase, transmembrane (endoplasmic
reticulum), mRNA (cDNA clone IMAGE:3162218), partial cds.
ACCESSION BC000580
VERSION BC000580.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1241)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1241)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: o Column: 1.
FEATURES Location/Qualifiers
source 1..1241
/db_xref="H-InvDB:HIT000085846"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3162218"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1241
/gene="P4HTM"
/gene_synonym="EGLN4"
/gene_synonym="HIFPH4"
/gene_synonym="P4H-TM"
/gene_synonym="PH-4"
/gene_synonym="PH4"
/gene_synonym="PHD4"
/db_xref="GeneID:54681"
/db_xref="HGNC:HGNC:28858"
CDS <1..1016
/gene="P4HTM"
/gene_synonym="EGLN4"
/gene_synonym="HIFPH4"
/gene_synonym="P4H-TM"
/gene_synonym="PH-4"
/gene_synonym="PH4"
/gene_synonym="PHD4"
/codon_start=3
/product="P4HTM protein"
/protein_id="AAH00580.1"
/db_xref="GeneID:54681"
/db_xref="HGNC:HGNC:28858"
/translation="KGLQRSQILPTEEYEEAMSTMQVSQLDLFRLLDQNRDGHLQLRE
VLAQTRLGNGWWMTPESIQEMYAAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAE
SSELVRNSHHTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHY
HAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNR
TYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLH
GGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGTDSQPEWALDRAYRDAR
VEL"
BASE COUNT 284 a 351 c 366 g 240 t
ORIGIN
1 tgaaggggtt acagcgcagc cagatcctgc ctactgaaga gtatgaagag gcaatgagca
61 ctatgcaggt cagccagctg gacctcttcc ggctgctgga ccagaaccgt gatgggcacc
121 ttcagctccg tgaggttctg gcccagactc gcctgggaaa tggatggtgg atgactccag
181 agagcattca ggagatgtac gccgcgatca aggctgaccc tgatggtgac ggagtgctga
241 gtctgcagga gttctccaac atggaccttc gggacttcca caagtacatg aggagccaca
301 aggcagagtc cagtgagctg gtgcggaaca gccaccatac ctggctctac cagggtgagg
361 gtgcccacca catcatgcgt gccatccgcc agagggtgct gcgcctcact cgcctgtcgc
421 ctgagatcgt ggagctcagc gagccgctgc aggttgttcg atatggtgag gggggccact
481 accatgccca cgtggacagt gggcctgtgt acccagagac catctgctcc cataccaagc
541 tggtagccaa cgagtctgta cccttcgaga cctcctgccg ctacatgaca gtgctgtttt
601 atttgaacaa cgtcactggt gggggcgaga ctgttttccc tgtagcagat aacagaacct
661 acgatgaaat gagtctgatt caggatgacg tggacctccg tgacacacgg aggcactgtg
721 acaagggaaa cctgcgtgtc aagccccaac agggcacagc agtcttctgg tacaactacc
781 tgcctgatgg gcaaggttgg gtgggtgacg tagacgacta ctcgctgcac gggggctgcc
841 tggtcacgcg cggcaccaag tggattgcca acaactggat taatgtggac cccagccgag
901 cgcggcaagc gctgttccaa caggagatgg cccgccttgc ccgagaaggg ggcaccgact
961 cacagcccga gtgggctctg gaccgggcct accgcgatgc gcgcgtggaa ctctgaggga
1021 agagttagcc ccggttccca gccgcgggtc gccagttgcc caagatcagg ggtccggctg
1081 tccttctgtc ctgctgcaga ctaaaggtct ggccaatgtc ttgccccacc ccgccagccg
1141 cgatacggcg cagttcctat attcatgtta tttattgtgt actgactcca tctgccccgt
1201 caaataaaaa accacaaggt tcgaaaaaaa aaaaaaaaaa a
//