LOCUS BC000576 1385 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens quinoid dihydropteridine reductase, mRNA (cDNA clone
MGC:1657 IMAGE:3162690), complete cds.
ACCESSION BC000576
VERSION BC000576.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1385)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1385)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC000576.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: m Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4506358.
FEATURES Location/Qualifiers
source 1..1385
/db_xref="H-InvDB:HIT000029747"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1657 IMAGE:3162690"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1385
/gene="QDPR"
/gene_synonym="DHPR"
/gene_synonym="PKU2"
/db_xref="GeneID:5860"
/db_xref="MIM:261630"
CDS 25..759
/gene="QDPR"
/gene_synonym="DHPR"
/gene_synonym="PKU2"
/codon_start=1
/product="QDPR protein"
/protein_id="AAH00576.1"
/db_xref="GeneID:5860"
/db_xref="MIM:261630"
/translation="MAAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASVDVVE
NEEASASIIVKMTDSFTEQADQVTAEVGKLLGEEKVDAILCVAGGWAGGNAKSKSLFK
NCDLMWKQSIWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQL
CQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITG
KNRPSSGSLIQVVTTEGRTELTPAYF"
misc_feature 55..642
/gene="QDPR"
/gene_synonym="DHPR"
/gene_synonym="PKU2"
/note="FabG; Region: Dehydrogenases with different
specificities (related to short-chain alcohol
dehydrogenases) [Secondary metabolites biosynthesis,
transport, and catabolism / General function prediction
only]"
/db_xref="CDD:COG1028"
BASE COUNT 317 a 316 c 387 g 365 t
ORIGIN
1 gggagccggg ctggcaggag caggatggcg gcggcggcgg ctgcaggcga ggcgcgccgg
61 gtgctggtgt acggcggcag gggcgctctg ggttctcgat gcgtgcaggc ttttcgggcc
121 cgcaactggt gggttgccag cgttgatgtg gtggagaatg aagaggccag cgctagcatc
181 attgttaaaa tgacagactc gttcactgag caggctgacc aggtgactgc tgaggttgga
241 aagctcttgg gtgaagagaa ggtggatgca attctttgcg ttgctggagg atgggccggg
301 ggcaatgcca aatccaagtc tctctttaag aactgtgacc tgatgtggaa gcagagcata
361 tggacatcga ccatctccag ccatctggct accaagcatc tcaaggaagg aggcctcctg
421 accttggctg gcgcaaaggc tgccctggat gggactcctg gtatgatcgg gtacggcatg
481 gccaagggtg ctgttcacca gctctgccag agcctggctg ggaagaacag cggcatgccg
541 cccggggcag ccgccatcgc tgtgctcccg gttaccctgg ataccccgat gaacaggaaa
601 tcaatgcctg aggctgactt cagctcctgg acacccttag aattcctagt tgaaactttc
661 catgactgga tcacagggaa aaaccgaccg agctcaggaa gcctaatcca ggtggtaacc
721 acagaaggaa ggacggaact caccccagca tatttttagg cctcatctca gtgcctatga
781 ggggcctgcc agaaaagtca ctaacctgtc tcagtgtggc cttgtccagc cttgtgtttt
841 ctgtaacccc tgtttgtggt acgagataat gagtcctatt tttctctcac ataatatgca
901 tttgctctcc taggacagtg taatacattt atgtgaagta aagacatgcg agactggtgg
961 cctgcaaata gcatccgtca atctgtgtta actgcatagg gagggctctg catagcacct
1021 gctatagcgg tgtcatgttg gatcgctttt gtgactgttc atctgtcctt gacagtggct
1081 gtcatcttga ctactttgtt gatttgttgg tattggggac attttaaagg ctgagttatt
1141 tttgaatgtc atgtttatgt catagacgta gttttcgcat ccttgaatta aactgcctta
1201 actccttttg tggtataagc aaaactccat ggactctgtc ctggtatcct tttcctgtgt
1261 ggttgccctg tgtcctctgg cctagggtta agtgtgcaag ataactactc gtgagtattc
1321 agaatgttgt tcctaataaa tgcacttgtt gtctgtcttc tttaaaaaaa aaaaaaaaaa
1381 aaaaa
//