LOCUS BC000562 1376 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens 2',5'-oligoadenylate synthetase 1, 40/46kDa, mRNA
(cDNA clone MGC:2253 IMAGE:3162421), complete cds.
ACCESSION BC000562
VERSION BC000562.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1376)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1376)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC000562.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: i Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8051620.
FEATURES Location/Qualifiers
source 1..1376
/db_xref="H-InvDB:HIT000029737"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2253 IMAGE:3162421"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1376
/gene="OAS1"
/gene_synonym="IFI-4"
/gene_synonym="OIASI"
/db_xref="GeneID:4938"
/db_xref="HGNC:HGNC:8086"
/db_xref="MIM:164350"
CDS 71..1165
/gene="OAS1"
/gene_synonym="IFI-4"
/gene_synonym="OIASI"
/codon_start=1
/product="2',5'-oligoadenylate synthetase 1, 40/46kDa"
/protein_id="AAH00562.4"
/db_xref="GeneID:4938"
/db_xref="HGNC:HGNC:8086"
/db_xref="MIM:164350"
/translation="MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKER
CFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEI
RRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLT
GSYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQN
CKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYY
DFKNPIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKN
WDGSPVSSWILLVRPPASSLPFIPAPLHEA"
BASE COUNT 366 a 359 c 330 g 321 t
ORIGIN
1 ctcagtcagc agaagagata aaagcaaaca ggtctgggag gcagttctgt tgccactctc
61 tctcctgtca atgatggatc tcagaaatac cccagccaaa tctctggaca agttcattga
121 agactatctc ttgccagaca cgtgtttccg catgcaaatc aaccatgcca ttgacatcat
181 ctgtgggttc ctgaaggaaa ggtgcttccg aggtagctcc taccctgtgt gtgtgtccaa
241 ggtggtaaag ggtggctcct caggcaaggg caccaccctc agaggccgat ctgacgctga
301 cctggttgtc ttcctcagtc ctctcaccac ttttcaggat cagttaaatc gccggggaga
361 gttcatccag gaaattagga gacagctgga agcctgtcaa agagagagag cattttccgt
421 gaagtttgag gtccaggctc cacgctgggg caacccccgt gcgctcagct tcgtactgag
481 ttcgctccag ctcggggagg gggtggagtt cgatgtgctg cctgcctttg atgccctggg
541 tcagttgact ggcagctata aacctaaccc ccaaatctat gtcaagctca tcgaggagtg
601 caccgacctg cagaaagagg gcgagttctc cacctgcttc acagaactac agagagactt
661 cctgaagcag cgccccacca agctcaagag cctcatccgc ctagtcaagc actggtacca
721 aaattgtaag aagaagcttg ggaagctgcc acctcagtat gccctggagc tcctgacggt
781 ctatgcttgg gagcgaggga gcatgaaaac acatttcaac acagcccagg gatttcggac
841 ggtcttggaa ttagtcataa actaccagca actctgcatc tactggacaa agtattatga
901 ctttaaaaac cccattattg aaaagtacct gagaaggcag ctcacgaaac ccaggcctgt
961 gatcctggac ccggcggacc ctacaggaaa cttgggtggt ggagacccaa agggttggag
1021 gcagctggca caagaggctg aggcctggct gaattaccca tgctttaaga attgggatgg
1081 gtccccagtg agctcctgga ttctgctggt gagacctcct gcttcctccc tgccattcat
1141 ccctgcccct ctccatgaag cttgagacat atagctggag accattcttt ccaaagaact
1201 tacctcttgc caaaggccat ttatattcat atagtgacag gctgtgctcc atattttaca
1261 gtcattttgg tcacaatcga gggtttctgg aattttcaca tcccttgtcc agaattcatt
1321 cccctaagag taataataaa taatctctaa caccaaaaaa aaaaaaaaaa aaaaaa
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