LOCUS BC000520 1536 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hydroxymethylbilane synthase, mRNA (cDNA clone
MGC:8561 IMAGE:2822949), complete cds.
ACCESSION BC000520
VERSION BC000520.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1536)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1536)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000520.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: j Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 66933007.
FEATURES Location/Qualifiers
source 1..1536
/db_xref="H-InvDB:HIT000029702"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8561 IMAGE:2822949"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1536
/gene="HMBS"
/gene_synonym="PBG-D"
/db_xref="GeneID:3145"
/db_xref="HGNC:HGNC:4982"
/db_xref="MIM:609806"
CDS 152..1237
/gene="HMBS"
/gene_synonym="PBG-D"
/codon_start=1
/product="hydroxymethylbilane synthase"
/protein_id="AAH00520.1"
/db_xref="GeneID:3145"
/db_xref="HGNC:HGNC:4982"
/db_xref="MIM:609806"
/translation="MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKA
SYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPT
VLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPH
LEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQG
ALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQL
YLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNL
GISLANLLLSKGAKNILDVARQLNDAH"
BASE COUNT 378 a 411 c 438 g 309 t
ORIGIN
1 gtgacgcgag gctctgcgga gaccaggagt cagactgtag gacgacctcg ggtcccacgt
61 gtccccggta ctcgccggcc ggagcccccg gcttcccggg gccgggggac cttagcggca
121 cccacacaca gcctactttc caagcggagc catgtctggt aacggcaatg cggctgcaac
181 ggcggaagaa aacagcccaa agatgagagt gattcgcgtg ggtacccgca agagccagct
241 tgctcgcata cagacggaca gtgtggtggc aacattgaaa gcctcgtacc ctggcctgca
301 gtttgaaatc attgctatgt ccaccacagg ggacaagatt cttgatactg cactctctaa
361 gattggagag aaaagcctgt ttaccaagga gcttgaacat gccctggaga agaatgaagt
421 ggacctggtt gttcactcct tgaaggacct gcccactgtg cttcctcctg gcttcaccat
481 cggagccatc tgcaagcggg aaaaccctca tgatgctgtt gtctttcacc caaaatttgt
541 tgggaagacc ctagaaaccc tgccagagaa gagtgtggtg ggaaccagct ccctgcgaag
601 agcagcccag ctgcagagaa agttcccgca tctggagttc aggagtattc ggggaaacct
661 caacacccgg cttcggaagc tggacgagca gcaggagttc agtgccatca tcctggcaac
721 agctggcctg cagcgcatgg gctggcacaa ccgggtgggg cagatcctgc accctgagga
781 atgcatgtat gctgtgggcc agggggcctt gggcgtggaa gtgcgagcca aggaccagga
841 catcttggat ctggtgggtg tgctgcacga tcccgagact ctgcttcgct gcatcgctga
901 aagggccttc ctgaggcacc tggaaggagg ctgcagtgtg ccagtagccg tgcatacagc
961 tatgaaggat gggcaactgt acctgactgg aggagtctgg agtctagacg gctcagatag
1021 catacaagag accatgcagg ctaccatcca tgtccctgcc cagcatgaag atggccctga
1081 ggatgaccca cagttggtag gcatcactgc tcgtaacatt ccacgagggc cccagttggc
1141 tgcccagaac ttgggcatca gcctggccaa cttgttgctg agcaaaggag ccaaaaacat
1201 cctggatgtt gcacggcagc ttaacgatgc ccattaactg gtttgtgggg cacagatgcc
1261 tgggttgctg ctgtccagtg cctacatccc gggcctcagt gccccattct cactgctatt
1321 tggggagtga ttaccccggg agactgaact gcagggttca agccttccag ggatttgcct
1381 caccttgggg ccttgatgac tgccttgcct cctcagtatg tgggggcttc atctctttag
1441 agaagtccaa gcaacagcct ttgaatgtaa ccaatcctac taataaacca gttctgaagg
1501 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
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