LOCUS BC000485 1959 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens dopa decarboxylase (aromatic L-amino acid
decarboxylase), mRNA (cDNA clone MGC:8351 IMAGE:2819761), complete
cds.
ACCESSION BC000485
VERSION BC000485.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1959)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1959)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: b Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 49472824.
FEATURES Location/Qualifiers
source 1..1959
/db_xref="H-InvDB:HIT000029669"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8351 IMAGE:2819761"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1959
/gene="DDC"
/gene_synonym="AADC"
/db_xref="GeneID:1644"
/db_xref="HGNC:HGNC:2719"
/db_xref="MIM:107930"
CDS 71..1513
/gene="DDC"
/gene_synonym="AADC"
/codon_start=1
/product="dopa decarboxylase (aromatic L-amino acid
decarboxylase)"
/protein_id="AAH00485.1"
/db_xref="GeneID:1644"
/db_xref="HGNC:HGNC:2719"
/db_xref="MIM:107930"
/translation="MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPA
AAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIG
FSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAAR
TKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMR
ASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAG
SAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLK
HSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLV
RQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAI
CSRTVESAHVQRAWEHIKELAADVLRAERE"
BASE COUNT 515 a 462 c 506 g 476 t
ORIGIN
1 gggcacgagg gaggacagag agcaagtcac tcccggctgc ctttttcacc tctgacagag
61 cccagacacc atgaacgcaa gtgaattccg aaggagaggg aaggagatgg tggattacgt
121 ggccaactac atggaaggca ttgagggacg ccaggtctac cctgacgtgg agcccgggta
181 cctgcggccg ctgatccctg ccgctgcccc tcaggagcca gacacgtttg aggacatcat
241 caacgacgtt gagaagataa tcatgcctgg ggtgacgcac tggcacagcc cctacttctt
301 cgcctacttc cccactgcca gctcgtaccc ggccatgctt gcggacatgc tgtgcggggc
361 cattggctgc atcggcttct cctgggcggc aagcccagca tgcacagagc tggagactgt
421 gatgatggac tggctcggga agatgctgga actaccaaag gcatttttga atgagaaagc
481 tggagaaggg ggaggagtga tccagggaag tgccagtgaa gccaccctgg tggccctgct
541 ggccgctcgg accaaagtga tccatcggct gcaggcagcg tccccagagc tcacacaggc
601 cgctatcatg gagaagctgg tggcttactc atccgatcag gcacactcct cagtggaaag
661 agctgggtta attggtggag tgaaattaaa agccatcccc tcagatggca acttcgccat
721 gcgtgcgtct gccctgcagg aagccctgga gagagacaaa gcggctggcc tgattccttt
781 ctttatggtt gccaccctgg ggaccacaac atgctgctcc tttgacaatc tcttagaagt
841 cggtcctatc tgcaacaagg aagacatatg gctgcacgtt gatgcagcct acgcaggcag
901 tgcattcatc tgccctgagt tccggcacct tctgaatgga gtggagtttg cagattcatt
961 caactttaat ccccacaaat ggctattggt gaattttgac tgttctgcca tgtgggtgaa
1021 aaagagaaca gacttaacgg gagcctttag actggacccc acttacctga agcacagcca
1081 tcaggattca gggcttatca ctgactaccg gcattggcag ataccactgg gcagaagatt
1141 tcgctctttg aaaatgtggt ttgtatttag gatgtatgga gtcaaaggac tgcaggctta
1201 tatccgcaag catgtccagc tgtcccatga gtttgagtca ctggtgcgcc aggatccccg
1261 ctttgaaatc tgtgtggaag tcattctggg gcttgtctgc tttcggctaa agggttccaa
1321 caaagtgaat gaagctcttc tgcaaagaat aaacagtgcc aaaaaaatcc acttggttcc
1381 atgtcacctc agggacaagt ttgtcctgcg ctttgccatc tgttctcgca cggtggaatc
1441 tgcccatgtg cagcgggcct gggaacacat caaagagctg gcggccgacg tgctgcgagc
1501 agagagggag taggagtgaa gccagctgca ggaatcaaaa attgaagaga gatatatctg
1561 aaaactggaa taagaagcaa ataaatatca tcctgccttc atggaactca gctgtctgtg
1621 gcttcccatg tctttctcca aagttatcca gagggttgtg attttgtctg cttagtatct
1681 catcaacaaa gaaatattat ttgctaatta aaaagttaat cttcatggcc atagctttta
1741 ttcattagct gtgatttttg ttgattaaaa cattatagat tttcatgttc ttgcagtcat
1801 cagaagtggt aggaaagcct cactgatata ttttccaggg caatcaatgt tcacgcaact
1861 tgaaattata tctgtggtct tcaaattgtc ttttgtcatg tggctaaatg cctaataaac
1921 aattcaagtg aaatactaaa aaaaaaaaaa aaaaaaaaa
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