LOCUS BC000401 2864 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens splicing factor 3b, subunit 2, 145kDa, mRNA (cDNA
clone IMAGE:2822659), partial cds.
ACCESSION BC000401
VERSION BC000401.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2864)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2864)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000401.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: i Column: 22.
FEATURES Location/Qualifiers
source 1..2864
/db_xref="H-InvDB:HIT000085833"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:2822659"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2864
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/db_xref="GeneID:10992"
/db_xref="MIM:605591"
CDS <1..2687
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/codon_start=3
/product="SF3B2 protein"
/protein_id="AAH00401.2"
/db_xref="GeneID:10992"
/db_xref="MIM:605591"
/translation="ATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQG
NREELVERLQSYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQ
PPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQE
ERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPL
GPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKIL
QLKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKK
PQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAF
KLTDDVKKEKEKEPEKLDKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSK
KKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRK
YLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDID
YQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNA
HKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLY
GDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPA
DSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAM
MGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEK
EDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF"
misc_feature 69..173
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/note="SAP; Region: SAP domain. The SAP (after SAF-A/B,
Acinus and PIAS) motif is a putative DNA binding domain
found in diverse nuclear proteins"
/db_xref="CDD:pfam02037"
misc_feature 1362..2099
/gene="SF3B2"
/gene_synonym="SAP145"
/gene_synonym="SF3b1"
/gene_synonym="SF3B145"
/gene_synonym="SF3b150"
/note="CUS1; Region: COG5182, CUS1, Splicing factor 3b,
subunit 2 [RNA processing and modification]"
/db_xref="CDD:COG5182"
BASE COUNT 766 a 745 c 833 g 520 t
ORIGIN
1 tggcgacgga gcatcccgag cctcccaaag cagaattgca gctgccgccg ccgccacctc
61 caggccacta tggcgcctgg gctgcccagg agcttcaggc caagttggca gagatcggag
121 ctccgatcca gggtaatcgc gaggagctgg tggagcggct gcagagctac acccgccaga
181 ctggcatcgt gctgaatcgg ccggttttga gaggggaaga tggggacaaa gccgctccac
241 ctcccatgtc ggcacagctc cctggaattc ccatgccacc accacctttg ggactccccc
301 ctctgcagcc tcctccgcca cccccaccac ctccaccagg ccttggcctt ggctttccta
361 tggcccaccc accaaatttg gggcccccgc ctcctctccg tgtgggtgag ccagtggcac
421 tgtcagagga ggagcggctg aagttggctc agcagcaggc ggcattgctg atgcagcagg
481 aggagcgtgc caagcagcag ggagatcatt cgctgaagga acatgagctc ttggagcagc
541 agaagcgggc agctgtgtta ctggagcagg aacgacagca ggagattgcc aagatgggca
601 ccccagtccc tcggccccca caagacatgg gccagattgg tgtgcgcact cctctgggtc
661 ctcgagtagc tgctccagtg ggcccagtgg gccccactcc tacagttttg cccatgggag
721 cccctgttcc ccggcctcgt ggtcccccac cgccccctgg agatgagaac agagagatgg
781 atgacccctc tgtgggcccc aagatccccc aggctttgga gaagatcctg cagctgaagg
841 agagccgcca ggaagagatg aattctcagc aggaggaaga ggaaatggaa acagatgctc
901 gctcgtccct gggccagtca gcgtcagaga ctgaggagga cacagtgtcc gtatctaaaa
961 aggagaaaaa ccggaagcgt aggaaccgaa agaagaagaa aaagccccag cgggtgcgag
1021 gggtgtcctc tgagagctct ggggaccggg agaaagactc aacccggtcc cgtggctctg
1081 attccccagc agctgatgtt gagattgagt atgtgactga agaacctgaa atttacgagc
1141 ccaactttat cttctttaag aggatctttg aggcttttaa gctcactgat gatgtgaaga
1201 aggagaaaga gaaagagcca gagaaacttg acaaactgga gaactctgca gcccccaaga
1261 agaagggatt tgaagaggag cacaaggaca gtgatgatga cagcagtgat gacgagcagg
1321 aaaagaagcc agaagccccc aagctgtcca agaagaagtt gcgccgaatg aaccgcttca
1381 ctgtggctga actcaagcag ctggtggctc ggcccgatgt cgtggagatg cacgatgtga
1441 cagcgcagga ccctaagctc ttggttcacc tcaaggccac tcggaactct gtgcctgtgc
1501 cacgccactg gtgttttaag cgcaaatacc tgcagggcaa acggggcatt gagaagcccc
1561 ccttcgagct gccagacttc atcaaacgca caggcatcca ggagatgcga gaggccctgc
1621 aggagaagga agaacagaag accatgaagt caaaaatgcg agagaaagtt cggcctaaga
1681 tgggcaaaat tgacatcgac taccagaaac tgcatgatgc cttcttcaag tggcagacca
1741 agccaaagct gaccatccat ggggacctgt actatgaggg gaaggagttc gagacacgac
1801 tgaaggagaa gaagccagga gatctgtctg atgagctaag gatttccttg gggatgccag
1861 taggaccaaa tgcccacaag gtccctcccc catggctgat tgccatgcag cgatatggac
1921 cacccccatc gtatcccaac ctgaaaatcc ctgggctgaa ctcgcccatc cctgagagct
1981 gttcctttgg gtaccatgct ggtggctggg gcaaacctcc agtggatgag actgggaaac
2041 cgctctatgg ggacgtgttt ggaaccaatg ctgctgaatt tcagaccaag actgaggaag
2101 aagagattga tcggacccct tggggggaac tggaaccatc tgatgaagaa tcctcagaag
2161 aagaggaaga ggaagaaagt gatgaagaca aaccagatga gacaggcttt attacccctg
2221 cagacagtgg ccttatcact cctggaggct tttcatcagt gcctgctgga atggagaccc
2281 ctgaactcat tgagctgagg aagaagaaga ttgaggaggc gatggacgga agtgagacac
2341 ctcagctctt cactgtgttg ccagagaaga gaacagccac tgttggaggg gccatgatgg
2401 gatcaaccca catttatgac atgtccacgg ttatgagccg gaagggcccg gctcctgagc
2461 tgcaaggtgt ggaagtggcg ctggcgcctg aagagttgga gctggatcct atggccatga
2521 cccagaagta tgaggagcat gtgcgggagc agcaggctca agtagagaag gaggacttca
2581 gtgacatggt ggctgagcac gctgccaaac agaagcaaaa aaaacggaaa gctcagcccc
2641 aggacagccg tgggggcagc aagaaatata aggagttcaa gttttaggtc ccctcacact
2701 agcccttttt ttggccctac gtctggatgc ctgggcttca cacaagaacc acctctcccg
2761 cagttcccaa ggacttgtca tttcatgttc ttattttaga cctgttttgt aaataaagct
2821 gtttcccaag gaaagagatg aaaaaaaaaa aaaaaaaaaa aaaa
//