LOCUS BC000375 2471 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens chromogranin B (secretogranin 1), mRNA (cDNA clone
MGC:8377 IMAGE:2820258), complete cds.
ACCESSION BC000375
VERSION BC000375.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2471)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2471)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000375.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: c Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4502806.
FEATURES Location/Qualifiers
source 1..2471
/db_xref="H-InvDB:HIT000029565"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8377 IMAGE:2820258"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2471
/gene="CHGB"
/db_xref="GeneID:1114"
/db_xref="HGNC:HGNC:1930"
/db_xref="MIM:118920"
CDS 105..2138
/gene="CHGB"
/codon_start=1
/product="chromogranin B (secretogranin 1)"
/protein_id="AAH00375.1"
/db_xref="GeneID:1114"
/db_xref="HGNC:HGNC:1930"
/db_xref="MIM:118920"
/translation="MQPTLLLSLLGAVGLAAVNSMPVDNRNHNEGMVTRCIIEVLSNA
LSKSSAPPITPECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRG
EAGAPGEEDIQGPTKADTEKWAEGGGHSRERADEPQWSLYPSDSQVSEEVKTRHSEKS
QREDEEEEEGENYQKGERGEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSE
THAAGHSQEKTHSREKSSQESGEEAGSQENHPQESKGQPRSQEESEEGEEDATSEVDK
RRTRPRHHHGRSRPDRSSQGGSLPSEEKGHPQEESEESNVSMASLGEKRDHHSTHYRA
SEEEPEYGEEIKGYPGVQAPEDLEWERYRGRGSEEYRAPRPQSEESWDEEDKRNYPSL
ELDKMAHGYGEESEEERGLEPGKGRHHRGRGGEPRAYFMSDTREEKRFLGEGHHRVQE
NQMDKARRHPQGAWKELDRNYLNYGEEGAPGKWQQQGDLQDTKENREEARFQDKQYSS
HHTAEKRKRLGELFNPYYDPLQWKSSHFERRDNMNDNFLEGEEENELTLNEKNFFPEY
NYDWWEKKPFSEDVNWGYEKRNLARVPKLDLKRQYDRVAQLDQLLHYRKKSAEFPDFY
DSEEPVSTHQEAENEKDRADQTVLTEDEKKELENLAAMDLELQKIAEKFSQRG"
BASE COUNT 802 a 543 c 711 g 415 t
ORIGIN
1 cacgctggtt ttccggggcc gctccatcgc gccttcctcc tgcgcctcgc ttctccggtc
61 cagccgccat cttcctttcc gcacaggggc cgccgagcgg ggccatgcag ccaacgctgc
121 ttctcagcct cctgggagcc gtggggctgg cggctgtcaa ttccatgcca gtggataaca
181 ggaaccacaa tgaaggaatg gtgactcgct gcatcattga ggtcctctca aatgccttgt
241 cgaagtccag cgctccaccc atcacccctg agtgccgcca agtcctgaag acgagtagaa
301 aagacgtcaa agacaaagag acaactgaaa atgaaaacac aaagtttgaa gtaagattgt
361 taagagaccc agctgatgcc tcggaagccc acgagtcctc cagcagggga gaggcaggag
421 ccccagggga ggaggacatc caaggcccaa caaaggcaga cacagagaaa tgggcagagg
481 gaggcgggca cagccgagag cgagcggatg agccccagtg gagcctctat ccctccgaca
541 gccaagtctc tgaagaagtg aagacacgcc attctgagaa gagccagaga gaggatgagg
601 aggaggagga gggagagaac tatcaaaaag gggagcgagg ggaagatagc agtgaagaga
661 aacaccttga agagccagga gagacacaaa acgcttttct caatgaaaga aagcaggctt
721 cagctataaa aaaagaggag ttagtggcca gatcggaaac acatgctgcc gggcattctc
781 aggagaagac acatagccga gagaagagta gccaggagag tggagaggag gcagggagcc
841 aggagaatca cccccaggag tctaaaggcc aaccccgaag ccaggaagaa tctgaggaag
901 gtgaggaaga tgccacctct gaggtggaca aacgacgcac gaggcccaga caccaccacg
961 ggaggagcag gcccgacagg tcctctcaag gagggagtct tccctctgag gaaaagggac
1021 acccccagga ggaatctgag gagtcaaacg tcagcatggc cagtttaggg gaaaagaggg
1081 accaccattc aacccactac agggcttcag aggaagaacc tgaatatgga gaagaaataa
1141 agggttatcc aggcgtccag gcccctgagg acctggagtg ggagcgctat aggggcagag
1201 gaagtgaaga atacagggct ccaagacctc agagtgagga gagttgggat gaggaggaca
1261 agagaaacta ccccagctta gagcttgata agatggcaca tggatatggt gaagaaagtg
1321 aggaagagag gggccttgag ccgggaaagg gacgccatca cagaggcagg ggaggggagc
1381 cacgtgccta tttcatgtct gacaccagag aagagaaaag gttcttgggt gaaggacacc
1441 accgtgtcca agaaaaccag atggacaagg caaggaggca tccacaaggt gcgtggaaag
1501 agctggacag aaattatctc aactacggtg aggaaggagc cccagggaag tggcagcagc
1561 agggagacct gcaggacact aaagaaaaca gggaggaagc taggtttcaa gataaacaat
1621 atagctccca tcacacagct gaaaagagga agagattagg ggaactgttc aacccatact
1681 acgaccctct ccagtggaag agcagccatt ttgaaagaag agacaacatg aatgacaatt
1741 ttctcgaggg tgaggaggaa aatgagctga ccttgaacga gaagaatttc ttcccagaat
1801 acaactatga ctggtgggag aaaaagccct tctctgagga tgtgaactgg gggtatgaga
1861 agagaaacct cgccagggtc cccaagctgg acctgaaaag gcaatatgac agggtggccc
1921 aactggacca gctccttcac tacaggaaga agtcagctga gtttccagac ttctatgatt
1981 ctgaggagcc ggtgagcacc caccaggagg cagaaaatga aaaggacagg gctgaccaga
2041 cagtcctgac agaggacgag aaaaaagaac tcgaaaactt ggctgcaatg gatttggaac
2101 tacagaagat agctgagaaa ttcagccaaa ggggctgact gtcattggag cggtgggcac
2161 tgttaagaag cagccatcac atgatctgtt tttcaccact tcactgaaag acaccattta
2221 tatacccaag ggcagaaagt agaacttact attcattaaa tgtttgacac aattggaatt
2281 gtctttaatt tctgtcagaa tgctattgaa aatgtgaatt gcatgacttg tagcatattc
2341 ttttctgcaa aatagacata ttaacatgct tatgacaatg actgtgctac tgtctttgga
2401 aaaatgtttg tctcagttgg aaataataaa agattcacct gagaccaaaa aaaaaaaaaa
2461 aaaaaaaaaa a
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