LOCUS BC000324 1858 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens granulin, mRNA (cDNA clone MGC:8480 IMAGE:2821810),
complete cds.
ACCESSION BC000324
VERSION BC000324.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1858)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1858)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000324.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: g Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 60498993.
FEATURES Location/Qualifiers
source 1..1858
/db_xref="H-InvDB:HIT000029518"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8480 IMAGE:2821810"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1858
/gene="GRN"
/gene_synonym="GEP"
/gene_synonym="GP88"
/gene_synonym="PCDGF"
/gene_synonym="PEPI"
/gene_synonym="PGRN"
/db_xref="GeneID:2896"
/db_xref="HGNC:HGNC:4601"
/db_xref="MIM:138945"
CDS 220..1536
/gene="GRN"
/gene_synonym="GEP"
/gene_synonym="GP88"
/gene_synonym="PCDGF"
/gene_synonym="PEPI"
/gene_synonym="PGRN"
/codon_start=1
/product="granulin"
/protein_id="AAH00324.1"
/db_xref="GeneID:2896"
/db_xref="HGNC:HGNC:4601"
/db_xref="MIM:138945"
/translation="MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRP
LLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRG
FHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCED
RVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDG
STCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPA
HTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGT
CEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCRDNRQGWACCPYR
QGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL"
BASE COUNT 351 a 584 c 546 g 377 t
ORIGIN
1 ggcgagagga agcagggagg agagtgattt gagtagaaaa gaaacacagc attccaggct
61 ggccccacct ctatattgat aagtagccaa tgggagcggg tagccctgat ccctggccaa
121 tggaaactga ggtaggcggg tcatcgcgct ggggtctgta gtctgagcgc tacccggttg
181 ctgctgccca aggaccgcgg agtcggacgc aggcagacca tgtggaccct ggtgagctgg
241 gtggccttaa cagcagggct ggtggctgga acgcggtgcc cagatggtca gttctgccct
301 gtggcctgct gcctggaccc cggaggagcc agctacagct gctgccgtcc ccttctggac
361 aaatggccca caacactgag caggcatctg ggtggcccct gccaggttga tgcccactgc
421 tctgccggcc actcctgcat ctttaccgtc tcagggactt ccagttgctg ccccttccca
481 gaggccgtgg catgcgggga tggccatcac tgctgcccac ggggcttcca ctgcagtgca
541 gacgggcgat cctgcttcca aagatcaggt aacaactccg tgggtgccat ccagtgccct
601 gatagtcagt tcgaatgccc ggacttctcc acgtgctgtg ttatggtcga tggctcctgg
661 gggtgctgcc ccatgcccca ggcttcctgc tgtgaagaca gggtgcactg ctgtccgcac
721 ggtgccttct gcgacctggt tcacacccgc tgcatcacac ccacgggcac ccaccccctg
781 gcaaagaagc tccctgccca gaggactaac agggcagtgg ccttgtccag ctcggtcatg
841 tgtccggacg cacggtcccg gtgccctgat ggttctacct gctgtgagct gcccagtggg
901 aagtatggct gctgcccaat gcccaacgcc acctgctgct ccgatcacct gcactgctgc
961 ccccaagaca ctgtgtgtga cctgatccag agtaagtgcc tctccaagga gaacgctacc
1021 acggacctcc tcactaagct gcctgcgcac acagtggggg atgtgaaatg tgacatggag
1081 gtgagctgcc cagatggcta tacctgctgc cgtctacagt cgggggcctg gggctgctgc
1141 ccttttaccc aggctgtgtg ctgtgaggac cacatacact gctgtcccgc ggggtttacg
1201 tgtgacacgc agaagggtac ctgtgaacag gggccccacc aggtgccctg gatggagaag
1261 gccccagctc acctcagcct gccagaccca caagccttga agagagatgt cccctgtgat
1321 aatgtcagca gctgtccctc ctccgatacc tgctgccgag acaaccgaca gggctgggcc
1381 tgctgtccct accgccaggg cgtctgttgt gctgatcggc gccactgctg tcctgctggc
1441 ttccgctgcg cagccagggg taccaagtgt ttgcgcaggg aggccccgcg ctgggacgcc
1501 cctttgaggg acccagcctt gagacagctg ctgtgaggga cagtactgaa gactctgcag
1561 ccctcgggac cccactcgga gggtgccctc tgctcaggcc tccctagcac ctccccctaa
1621 ccaaattctc cctggacccc attctgagct ccccatcacc atgggaggtg gggcctcaat
1681 ctaaggcctt ccctgtcaga agggggttgt ggcaaaagcc acattacaag ctgccatccc
1741 ctccccgttt cagtggaccc tgtggccagg tgcttttccc tatccacagg ggtgtttgtg
1801 tgtgtgcgcg tgtgcgtttc aataaagttt gtacactttc aaaaaaaaaa aaaaaaaa
//