LOCUS BC000309 1259 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens spermidine synthase, mRNA (cDNA clone MGC:8422
IMAGE:2820975), complete cds.
ACCESSION BC000309
VERSION BC000309.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1259)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1259)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000309.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: e Column: 5.
FEATURES Location/Qualifiers
source 1..1259
/db_xref="H-InvDB:HIT000029506"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8422 IMAGE:2820975"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1259
/gene="SRM"
/gene_synonym="PAPT"
/gene_synonym="SPDSY"
/gene_synonym="SPS1"
/db_xref="GeneID:6723"
/db_xref="HGNC:HGNC:11296"
/db_xref="MIM:182891"
CDS 58..966
/gene="SRM"
/gene_synonym="PAPT"
/gene_synonym="SPDSY"
/gene_synonym="SPS1"
/codon_start=1
/product="spermidine synthase"
/protein_id="AAH00309.1"
/db_xref="GeneID:6723"
/db_xref="HGNC:HGNC:11296"
/db_xref="MIM:182891"
/translation="MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHR
RSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGG
GDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFM
KQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIK
EMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQL
KYYNSDVHRAAFVLPEFARKALNDVS"
BASE COUNT 239 a 438 c 353 g 229 t
ORIGIN
1 cggcgccgcg cggcctgcag tcccgggccc gcgccccgcg ccgcccgccc gcccgccatg
61 gagcccggcc ccgacggccc cgccgcctcc ggccccgccg ccatccgcga gggctggttc
121 cgcgagacct gcagcctgtg gcccggccag gccctgtcgc tgcaggtgga gcagctgctc
181 caccaccggc gctcgcgcta ccaggacatc ctcgtcttcc gcagtaagac ctatggcaac
241 gtgctggtgt tggacggtgt catccagtgc acggagagag acgagttctc ctaccaggag
301 atgatcgcca acctgcctct ctgcagccac cccaacccgc gaaaggtgct gatcatcggg
361 ggcggagatg gaggtgtcct gcgggaggtg gtgaagcacc cctccgtgga gtccgtggtc
421 cagtgtgaga tcgacgagga tgtcatccaa gtctccaaga agttcctgcc aggcatggcc
481 attggctact ctagctcgaa gctgacccta catgtgggtg acggttttga gttcatgaaa
541 cagaatcagg atgccttcga cgtgatcatc actgactcct cagaccccat gggccccgcc
601 gaaagtctct tcaaggagtc ctattaccag ctcatgaaga cagccctcaa ggaagatggt
661 gtcctctgct gccagggcga gtgccagtgg ctgcacctgg acctcatcaa ggagatgcgg
721 cagttctgcc agtccctgtt ccccgtggtg gcctatgcct actgcaccat ccccacctac
781 cccagcggcc agatcggctt catgctgtgc agcaagaacc cgagcacgaa cttccaggag
841 ccggtgcagc cgctgacaca gcagcaggtg gcgcagatgc agctgaagta ctacaactcc
901 gacgtgcacc gcgccgcctt tgtgctgccc gagtttgccc gcaaggccct gaatgatgtg
961 agctgagccc aggcgccacc actgatgcca cccaggacct cggaccttgg agcctgcggg
1021 gtgcctcggc ccctccagcc ccgggccgga cctcctgctg gctctcgccc accaaccaag
1081 tgttacaagc cccagaatgc tgcccggcct gccctgctgg gcggactgtc tgtgtgtctg
1141 tctctctggc gttccacctc caagcctata ccagctgtgt acagcgccat ctctctgcct
1201 tctgttgccc ctcactcacc aaacacgtgt atttatagca aaaaaaaaaa aaaaaaaaa
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