LOCUS BC000305 1373 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens caspase 6, apoptosis-related cysteine peptidase, mRNA
(cDNA clone MGC:8388 IMAGE:2820468), complete cds.
ACCESSION BC000305
VERSION BC000305.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1373)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1373)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Nov 6, 2003 this sequence version replaced BC000305.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: c Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14916482.
FEATURES Location/Qualifiers
source 1..1373
/db_xref="H-InvDB:HIT000029502"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8388 IMAGE:2820468"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1373
/gene="CASP6"
/gene_synonym="MCH2"
/db_xref="GeneID:839"
/db_xref="HGNC:HGNC:1507"
/db_xref="MIM:601532"
CDS 27..908
/gene="CASP6"
/gene_synonym="MCH2"
/codon_start=1
/product="caspase 6, apoptosis-related cysteine peptidase"
/protein_id="AAH00305.1"
/db_xref="GeneID:839"
/db_xref="HGNC:HGNC:1507"
/db_xref="MIM:601532"
/translation="MSSASGLRRGHPAGGEENMTETDAFYKREMFDPAEKYKMDHRRR
GIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHE
VSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFII
QACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYS
HRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVP
CFASMLTKKLHFFPKSN"
BASE COUNT 407 a 289 c 335 g 342 t
ORIGIN
1 ggtgtctggc tgcgcgtttg gctgcaatga gctcggcctc ggggctccgc agggggcacc
61 cggcaggtgg ggaagaaaac atgacagaaa cagatgcctt ctataaaaga gaaatgtttg
121 atccggcaga aaagtacaaa atggaccaca ggaggagagg aattgcttta atcttcaatc
181 atgagaggtt cttttggcac ttaacactgc cagaaaggcg gggcacctgc gcagatagag
241 acaatcttac ccgcaggttt tcagatctag gatttgaagt gaaatgcttt aatgatctta
301 aagcagaaga actactgctc aaaattcatg aggtgtcaac tgttagccac gcagatgccg
361 attgctttgt gtgtgtcttc ctgagccatg gcgaaggcaa tcacatttat gcatatgatg
421 ctaaaatcga aattcagaca ttaactggct tgttcaaagg agacaagtgt cacagcctgg
481 ttggaaaacc caagatattt atcattcagg catgtcgggg aaaccagcac gatgtgccag
541 tcattccttt ggatgtagta gataatcaga cagagaagtt ggacaccaac ataactgagg
601 tggatgcagc ctccgtttac acgctgcctg ctggagctga cttcctcatg tgttactctg
661 ttgcagaagg atattattct caccgggaaa ctgtgaacgg ctcatggtac attcaagatt
721 tgtgtgagat gttgggaaaa tatggctcct ccttagagtt cacagaactc ctcacactgg
781 tgaacaggaa agtttctcag cgccgagtgg acttttgcaa agacccaagt gcaattggaa
841 agaagcaggt tccctgtttt gcctcaatgc taactaaaaa gctgcatttc tttccaaaat
901 ctaattaatt aatagaggct atctaatttt acactctgta ttgaaaatgg ctttctcagc
961 caggcgtggt tactcacacc tgtaatccca gcactttggg agtccaaggt gggcggatca
1021 cctgaggtcg ggagttcgag accagcctga ccaacatgga gaagccccgt ctctactaaa
1081 aatgcaaaaa aaaatttagc taggcatggc ggcgcatgcc tgcaatccca gctacttgga
1141 aggctgaggc aggagaatca cttgaaccca ggaggtggag gctgcggtga gccgagattg
1201 cgccattgca ctccagcctg ggcaacgagt gaaactccgt ctcaaaaaaa agaaaatgtc
1261 tttctcttcc ttttatataa atatcgttag ggtgaagcat tatggtccaa tgattcaaat
1321 gttttaaagt ttaatgccta gcagagaact gccttaaaaa aaaaaaaaaa aaa
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