LOCUS BC000303 1861 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens phosphoglycerate dehydrogenase, mRNA (cDNA clone
MGC:8384 IMAGE:2820369), complete cds.
ACCESSION BC000303
VERSION BC000303.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1861)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1861)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000303.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: c Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23308576.
FEATURES Location/Qualifiers
source 1..1861
/db_xref="H-InvDB:HIT000029500"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8384 IMAGE:2820369"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1861
/gene="PHGDH"
/gene_synonym="3-PGDH"
/gene_synonym="3PGDH"
/gene_synonym="MGC3017"
/gene_synonym="PDG"
/gene_synonym="PGAD"
/gene_synonym="PGD"
/gene_synonym="PGDH"
/gene_synonym="SERA"
/db_xref="GeneID:26227"
/db_xref="HGNC:HGNC:8923"
/db_xref="MIM:606879"
CDS 68..1669
/gene="PHGDH"
/gene_synonym="3-PGDH"
/gene_synonym="3PGDH"
/gene_synonym="MGC3017"
/gene_synonym="PDG"
/gene_synonym="PGAD"
/gene_synonym="PGD"
/gene_synonym="PGDH"
/gene_synonym="SERA"
/codon_start=1
/product="phosphoglycerate dehydrogenase"
/protein_id="AAH00303.1"
/db_xref="GeneID:26227"
/db_xref="HGNC:HGNC:8923"
/db_xref="MIM:606879"
/translation="MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAE
LQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGN
SLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREV
ATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLN
DNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHE
NVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIG
LAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVN
AKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNG
AVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHV
MGISSLLPSLEAWKQHVTEAFQFHF"
BASE COUNT 414 a 517 c 552 g 378 t
ORIGIN
1 ccgaaccgca gcttcttggc ttaggtactt ctactcacag cggccgattc cgaggccaac
61 tccagcaatg gcttttgcaa atctgcggaa agtgctcatc agtgacagcc tggacccttg
121 ctgccggaag atcttgcaag atggagggct gcaggtggtg gaaaagcaga accttagcaa
181 agaggagctg atagcggagc tgcaggactg tgaaggcctt attgttcgct ctgccaccaa
241 ggtgaccgct gatgtcatca acgcagctga gaaactccag gtggtgggca gggctggcac
301 aggtgtggac aatgtggatc tggaggccgc aacaaggaag ggcatcttgg ttatgaacac
361 ccccaatggg aacagcctca gtgccgcaga actcacttgt ggaatgatca tgtgcctggc
421 caggcagatt ccccaggcga cggcttcgat gaaggacggc aaatgggagc ggaagaagtt
481 catgggaaca gagctgaatg gaaagaccct gggaattctt ggcctgggca ggattgggag
541 agaggtagct acccggatgc agtcctttgg gatgaagact atagggtatg accccatcat
601 ttccccagag gtctcggcct cctttggtgt tcagcagctg cccctggagg agatctggcc
661 tctctgtgat ttcatcactg tgcacactcc tctcctgccc tccacgacag gcttgctgaa
721 tgacaacacc tttgcccagt gcaagaaggg ggtgcgtgtg gtgaactgtg cccgtggagg
781 gatcgtggac gaaggcgccc tgctccgggc cctgcagtct ggccagtgtg ccggggctgc
841 actggacgtg tttacggaag agccgccacg ggaccgggcc ttggtggacc atgagaatgt
901 catcagctgt ccccacctgg gtgccagcac caaggaggct cagagccgct gtggggagga
961 aattgctgtt cagttcgtgg acatggtgaa ggggaaatct ctcacggggg ttgtgaatgc
1021 ccaggccctt accagtgcct tctctccaca caccaagcct tggattggtc tggcagaagc
1081 tctggggaca ctgatgcgag cctgggctgg gtcccccaaa gggaccatcc aggtgataac
1141 acagggaaca tccctgaaga atgctgggaa ctgcctaagc cccgcagtca ttgtcggcct
1201 cctgaaagag gcttccaagc aggcggatgt gaacttggtg aacgctaagc tgctggtgaa
1261 agaggctggc ctcaatgtca ccacctccca cagccctgct gcaccagggg agcaaggctt
1321 cggggaatgc ctcctggccg tggccctggc aggcgcccct taccaggctg tgggcttggt
1381 ccaaggcact acacctgtac tgcaggggct caatggagct gtcttcaggc cagaagtgcc
1441 tctccgcagg gacctgcccc tgctcctatt ccggactcag acctctgacc ctgcaatgct
1501 gcctaccatg attggcctcc tggcagaggc aggcgtgcgg ctgctgtcct accagacttc
1561 actggtgtca gatggggaga cctggcacgt catgggcatc tcctccttgc tgcccagcct
1621 ggaagcgtgg aagcagcatg tgactgaagc cttccagttc cacttctaac cttggagctc
1681 actggtccct gcctctgggg cttttctgaa gaaacccacc cactgtgatc aatagggaga
1741 gaaaatccac attcttgggc tgaacgcggg cctctgacac tgcttacact gcactctgac
1801 cctgtagtac agcaataacc gtctaataaa gagcctaccc ccaaaaaaaa aaaaaaaaaa
1861 a
//