LOCUS BC000299 1966 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma, mRNA (cDNA clone MGC:8374 IMAGE:2820134),
complete cds.
ACCESSION BC000299
VERSION BC000299.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1966)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1966)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000299.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: c Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21361093.
FEATURES Location/Qualifiers
source 1..1966
/db_xref="H-InvDB:HIT000029497"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8374 IMAGE:2820134"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1966
/gene="IKBKG"
/gene_synonym="FIP-3"
/gene_synonym="FIP3"
/gene_synonym="Fip3p"
/gene_synonym="IKK-gamma"
/gene_synonym="IP"
/gene_synonym="IP2"
/gene_synonym="NEMO"
/db_xref="GeneID:8517"
/db_xref="MIM:300248"
CDS 121..1380
/gene="IKBKG"
/gene_synonym="FIP-3"
/gene_synonym="FIP3"
/gene_synonym="Fip3p"
/gene_synonym="IKK-gamma"
/gene_synonym="IP"
/gene_synonym="IP2"
/gene_synonym="NEMO"
/codon_start=1
/product="IKBKG protein"
/protein_id="AAH00299.1"
/db_xref="GeneID:8517"
/db_xref="MIM:300248"
/translation="MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSE
QGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARK
LVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRL
EAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQ
AASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVA
KQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLE
QLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEP
PDFCCPKCQYQAPDMDTLQIHVMECIE"
BASE COUNT 416 a 580 c 630 g 340 t
ORIGIN
1 gaagggcgac cgcgaaactg ggactttctc ggagcgccgg ggccctacca gcgttcacag
61 tccgccgctc ccacccttct cacgtctgac ggactctgct gacagccctt gccctgttgg
121 atgaataggc acctctggaa gagccaactg tgtgagatgg tgcagcccag tggtggcccg
181 gcagcagatc aggacgtact gggcgaagag tctcctctgg ggaagccagc catgctgcac
241 ctgccttcag aacagggcgc tcctgagacc ctccagcgct gcctggagga gaatcaagag
301 ctccgagatg ccatccggca gagcaaccag attctgcggg agcgctgcga ggagcttctg
361 catttccaag ccagccagag ggaggagaag gagttcctca tgtgcaagtt ccaggaggcc
421 aggaaactgg tggagagact cggcctggag aagctcgatc tgaagaggca gaaggagcag
481 gctctgcggg aggtggagca cctgaagaga tgccagcagc agatggctga ggacaaggcc
541 tctgtgaaag cccaggtgac gtccttgctc ggggagctgc aggagagcca gagtcgcttg
601 gaggctgcca ctaaggaatg ccaggctctg gagggtcggg cccgggcggc cagcgagcag
661 gcgcggcagc tggagagtga gcgcgaggcg ctgcagcagc agcacagcgt gcaggtggac
721 cagctgcgca tgcagggcca gagcgtggag gccgcgctcc gcatggagcg ccaggccgcc
781 tcggaggaga agaggaagct ggcccagttg caggtggcct atcaccagct cttccaagaa
841 tacgacaacc acatcaagag cagcgtggtg ggcagtgagc ggaagcgagg aatgcagctg
901 gaagatctca aacagcagct ccagcaggcc gaggaggccc tggtggccaa acaggaggtg
961 atcgataagc tgaaggagga ggccgagcag cacaagattg tgatggagac cgttccggtg
1021 ctgaaggccc aggcggatat ctacaaggcg gacttccagg ctgagaggca ggcccgggag
1081 aagctggccg agaagaagga gctcctgcag gagcagctgg agcagctgca gagggagtac
1141 agcaaactga aggccagctg tcaggagtcg gccaggatcg aggacatgag gaagcggcat
1201 gtcgaggtct cccaggcccc cttgcccccc gcccctgcct acctctcctc tcccctggcc
1261 ctgcccagcc agaggaggag cccccccgag gagccacctg acttctgctg tcccaagtgc
1321 cagtatcagg cccctgatat ggacaccctg cagatacatg tcatggagtg cattgagtag
1381 ggccggccag tgcaaggcca ctgcctgccg aggacgtgcc cgggaccgtg cagtctgcgc
1441 tttcctctcc cgcctgccta gcccaggatg aagggctggg tggccacaac tgggatgcca
1501 cctggagccc cacccaggag ctggccgcgg caccttacgc ttcagctgtt gatccgctgg
1561 tcccctcttt tggggtagat gcggccccga tcaggcctga ctcgctgctc tttttgttcc
1621 cttctgtctg ctcgaaccac ttgcctcggg ctaatccctc cctcttcctc cacccggcac
1681 tggggaagtc aagaatgggg cctggggctc tcagggagaa ctgcttcccc tggcagagct
1741 gggtggccgc tcttcctccc accggacacc gacccgcccg ccgctgtgcc ctgggagtgc
1801 tgccctctta ccatgcacac gggtgctctc cttttgggct gcatgctatt ccattttgca
1861 gccagaccga tgtgtattta accagtcact attgatggac atttgggttg tttcccatct
1921 ttttgttacc ataaataatg gcatagtaaa aaaaaaaaaa aaaaaa
//