LOCUS BC000249 3109 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens phosphodiesterase 6B, cGMP-specific, rod, beta, mRNA
(cDNA clone MGC:1689 IMAGE:3356353), complete cds.
ACCESSION BC000249
VERSION BC000249.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3109)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3109)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: g Column: 6.
FEATURES Location/Qualifiers
source 1..3109
/db_xref="H-InvDB:HIT000029459"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1689 IMAGE:3356353"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3109
/gene="PDE6B"
/gene_synonym="CSNB3"
/gene_synonym="rd1"
/gene_synonym="RP40"
/db_xref="GeneID:5158"
/db_xref="HGNC:HGNC:8786"
/db_xref="MIM:180072"
CDS 44..2605
/gene="PDE6B"
/gene_synonym="CSNB3"
/gene_synonym="rd1"
/gene_synonym="RP40"
/codon_start=1
/product="phosphodiesterase 6B, cGMP-specific, rod, beta"
/protein_id="AAH00249.1"
/db_xref="GeneID:5158"
/db_xref="HGNC:HGNC:8786"
/db_xref="MIM:180072"
/translation="MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDGCPPDC
DSLRDLCQVEESTALLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNG
VAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHF
SSFADELTDYKTKNMLATPIMNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATL
YLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCERYSVG
LLDMTKEKEFFDVWSVLMGESQPYSGPRTPDGREIVFYKVIDYILHGKEEIKVIPTPS
ADHWALASGLPSYVAESGFICNIMNASADEMFKFQEGALDDSGWLIKNVLSMPIVNKK
EEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVMNTDTYDKMNKLENRKDIAQD
MVLYHVKCDRDEIQLILPTRARLGKEPADCDEDELGEILKEELPGPTTFDIYEFHFSD
LECTELDLVKCGIQMYYELGVVRKFQIPQEVLVRFLFSISKGYRRITYHNWRHGFNVA
QTMFTLLMTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSI
LERHHLEFGKFLLSEETLNIYQNLNRRQHDHVIHLMDIAIIATDLALYFKKRAMFQKI
VDESKNYQDKKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEF
WEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFD
RLQNNRKEWKALADEYEAKVKALEEKEEEERVAAKKGTEICNGGPAPKSSTCCIL"
BASE COUNT 747 a 866 c 875 g 621 t
ORIGIN
1 tgcgtgcctg gagcagcagc gtctccaggg acaggcagcc accatgagcc tcagtgagga
61 gcaggcccgg agctttctgg accagaaccc cgattttgcc cgccagtact ttgggaagaa
121 actgagccct gagaatgtgg ccgcggcctg cgaggacggg tgcccgccgg actgcgacag
181 cctccgggac ctctgccagg tggaggagag cacggcgctg ctggagctgg tgcaggatat
241 gcaggagagc atcaacatgg agcgcgtggt cttcaaggtc ctgcggcgcc tctgcaccct
301 cctgcaggcc gaccgctgca gcctcttcat gtaccgccag cgcaacggcg tggccgagct
361 ggccaccagg cttttcagcg tgcagccgga cagcgtcctg gaggactgcc tggtgccccc
421 cgactccgag atcgtcttcc cactggacat cggggtcgtg ggccacgtgg ctcagaccaa
481 aaagatggtg aacgtcgagg acgtggccga gtgccctcac ttcagctcat ttgctgacga
541 gctcactgac tacaagacaa agaatatgct ggccacaccc atcatgaatg gcaaagacgt
601 cgtggcggtg atcatggcag tgaacaagct caacggccca ttcttcacca gcgaagacga
661 agatgtgttc ttgaagtacc tgaattttgc cacgttgtac ctgaagatct atcacctgag
721 ctacctccac aactgcgaga cgcgccgcgg ccaggtgctg ctgtggtcgg ccaacaaggt
781 gtttgaggag ctgacggaca tcgagaggca gttccacaag gccttctaca cggtgcgggc
841 ctacctcaac tgcgagcggt actccgtggg cctcctggac atgaccaagg agaaggaatt
901 ttttgacgtg tggtctgtgc tgatgggaga gtcccagccg tactcgggcc cacgcacgcc
961 tgatggccgg gaaattgtct tctacaaagt gatcgactac atcctccacg gcaaggagga
1021 gatcaaggtc attcccacac cctcagccga tcactgggcc ctggccagcg gccttccaag
1081 ctacgtggca gaaagcggct ttatttgtaa catcatgaat gcttccgctg acgaaatgtt
1141 caaatttcag gaaggggccc tggacgactc cgggtggctc atcaagaatg tgctgtccat
1201 gcccatcgtc aacaagaagg aggagattgt gggagtcgcc acattttaca acaggaaaga
1261 cgggaagccc tttgacgaac aggacgaggt tctcatggag tccctgacac agttcctggg
1321 ctggtcagtg atgaacaccg acacctacga caagatgaac aagctggaga accgcaagga
1381 catcgcacag gacatggtcc tttaccacgt gaagtgcgac agggacgaga tccagctcat
1441 cctgccaacc agagcgcgcc tggggaagga gcctgctgac tgcgatgagg acgagctggg
1501 cgaaatcctg aaggaggagc tgccagggcc caccacattt gacatctacg aattccactt
1561 ctctgacctg gagtgcaccg aactggacct ggtcaaatgt ggcatccaga tgtactacga
1621 gctgggcgtg gtccgaaagt tccagatccc ccaggaggtc ctggtgcggt tcctgttctc
1681 catcagcaaa gggtaccgga gaatcaccta ccacaactgg cgccacggct tcaacgtggc
1741 ccagacgatg ttcacgctgc tcatgaccgg caaactgaag agctactaca cggacctgga
1801 ggccttcgcc atggtgacag ccggcctgtg ccatgacatc gaccaccgcg gcaccaacaa
1861 cctgtaccag atgaagtccc agaacccctt ggctaagctc cacggctcct cgattttgga
1921 gcggcaccac ctggagtttg ggaagttcct gctctcggag gagaccctga acatctacca
1981 gaacctgaac cggcggcagc acgatcacgt gatccacctg atggacatcg ccatcatcgc
2041 cacggacctg gccctgtact tcaagaagag agcgatgttt cagaagatcg tggatgagtc
2101 caagaactac caggacaaga agagctgggt ggagtacctg tccctggaga cgacccggaa
2161 ggagatcgtc atggccatga tgatgacagc ctgcgacctg tctgccatca ccaagccctg
2221 ggaagtccag agcaaggtcg cacttctcgt ggctgctgag ttctgggagc aaggtgactt
2281 ggaaaggaca gtcttggatc agcagcccat tcctatgatg gaccggaaca aggcggccga
2341 gctccccaag ctgcaagtgg gcttcatcga cttcgtgtgc acattcgtgt acaaggagtt
2401 ctctcgtttc cacgaagaga tcctgcccat gttcgaccga ctgcagaaca ataggaaaga
2461 gtggaaggcg ctggctgatg agtatgaggc caaagtgaag gctctggagg agaaggagga
2521 ggaggagagg gtggcagcca agaaaggcac agaaatttgc aatggcggcc cagcacccaa
2581 gtcttcaacc tgctgtatcc tgtgagcact ggtcccatgg ggaccctatg gctccctcaa
2641 tcttcaccca ctaggatttg ggttctgcct gtggctattt gctacaagag gttaggaagc
2701 ccaagaaaat gactgaagat cattctggat attttaattt tttttttttt ttttttttga
2761 gatggagtct tgctctgtca cccaggctgg agtgccgtgg cacgatctca gctcactgca
2821 acctccacct cccaggttca agcgattctc gtgcctcagc ctcctgagta gctgggacta
2881 caggcgccca ccaccacaca tggctaattt ttgtattttc agtacagatg gggtttcacc
2941 atattgggca ggctggtctc gaactcctga cctcaggtga tcacccgcct cagcttcctg
3001 aagtgctggg attacaggca tgagccacca cgcccagcct gtttttataa actgaagcca
3061 actgtgaata aactgtagcc tacaaaaaaa aaaaaaaaaa aaaaaaaaa
//