LOCUS BC000235 3137 bp mRNA linear HUM 27-OCT-2006
DEFINITION Homo sapiens lon peptidase 1, mitochondrial, mRNA (cDNA clone
MGC:1498 IMAGE:3350958), complete cds.
ACCESSION BC000235
VERSION BC000235.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3137)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3137)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: e Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21396488.
FEATURES Location/Qualifiers
source 1..3137
/db_xref="H-InvDB:HIT000029449"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1498 IMAGE:3350958"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3137
/gene="LONP1"
/gene_synonym="hLON"
/gene_synonym="LON"
/gene_synonym="LonHS"
/gene_synonym="LONP"
/gene_synonym="MGC1498"
/gene_synonym="PIM1"
/db_xref="GeneID:9361"
/db_xref="HGNC:HGNC:9479"
/db_xref="MIM:605490"
CDS 6..2885
/gene="LONP1"
/gene_synonym="hLON"
/gene_synonym="LON"
/gene_synonym="LonHS"
/gene_synonym="LONP"
/gene_synonym="MGC1498"
/gene_synonym="PIM1"
/codon_start=1
/product="lon peptidase 1, mitochondrial"
/protein_id="AAH00235.1"
/db_xref="GeneID:9361"
/db_xref="HGNC:HGNC:9479"
/db_xref="MIM:605490"
/translation="MAASTGYVRLWGAARCWVLRRPMLAAAGGRVPTAAGAWLLRGQR
TCDASPPWALWGRGPAIGGQWRGFWEASSRGGGAFSGGEDASEGGAEEGAGGAGGSAG
AGEGPVITALTPMTIPDVFPHLPLIAITRNPVFPRFIKIIEVKNKKLVELLRRKVRLA
QPYVGVFLKRDDSNESDVVESLDEIYHTGTFAQIHEMQDLGDKLRMIVMGHRRVHISR
QLEVEPEEPEAENKHKPRRKSKRGKKEAEDELSARHPAELAMEPTPELPAEVLMVEVE
NVVHEDFQVTEEVKALTAEIVKTIRDIIALNPLYRESVLQMMQAGQRVVDNPIYLSDM
GAALTGAESHELQDVLEETNIPKRLYKALSLLKKEFELSKLQQRLGREVEEKIKQTHR
KYLLQEQLKIIKKELGLEKDDKDAIEEKFRERLKELVVPKHVMDVVDEELSKLGLLDN
HSSEFNVTRNYLDWLTSIPWGKYSNENLDLARAQAVLEEDHYGMEDVKKRILEFIAVS
QLRGSTQGKILCFYGPPGVGKTSIARSIARALNREYFRFSVGGMTDVAEIKGHRRTYV
GAMPGKIIQCLKKTKTENPLILIDEVDKIGRGYQGDPSSALLELLDPEQNANFLDHYL
DVPVDLSKVLFICTANVTDTIPEPLRDRMEMINVSGYVAQEKLAIAERYLVPQARALC
GLDESKAKLSSDVLTLLIKQYCRESGVRNLQKQVEKVLRKSAYKIVSGEAESVEVTPE
NLQDFVGKPVFTVERMYDVTPPGVVMGLAWTAMGGSTLFVETSLRRPQDKDAKGDKDG
SLEVTGQLGEVMKESARIAYTFARAFLMQHAPANDYLVTSHIHLHVPEGATPKDGPSA
GCTIVTALLSLAMGRPVRQNLAMTGEVSLTGKILPVGGIKEKTIAAKRAGVTCIVLPA
ENKKDFYDLAAFITEGLEVHFVEHYREIFDIAFPDEQAEALAVER"
BASE COUNT 711 a 888 c 1044 g 494 t
ORIGIN
1 gggctatggc ggcgagcact ggctacgtgc gactgtgggg agcggcgcgg tgctgggtgc
61 tgcggcggcc gatgctggcc gccgccgggg ggcgggttcc cactgcagca ggagcgtggt
121 tgctccgagg ccagcggacc tgcgacgcct ctcctccttg ggcactgtgg ggccgaggcc
181 cggcaattgg gggccaatgg cgggggtttt gggaagcgag cagccgcggc ggaggcgcat
241 tctcgggggg cgaggacgcc tccgagggcg gcgcggagga aggagccggc ggcgcggggg
301 gcagcgcggg cgccggggaa ggcccggtca taacggcgct cacgcccatg acgatccccg
361 atgtgtttcc gcacctgccg ctcatcgcca tcacccgcaa cccggtgttc ccgcgcttta
421 tcaagattat cgaggttaaa aataagaagt tggttgagct gctgagaagg aaagttcgtc
481 tcgcccagcc ttatgtcggc gtctttctaa agagagatga cagcaatgag tcggatgtgg
541 tcgagagcct ggatgaaatc taccacacgg ggacgtttgc ccagatccat gagatgcagg
601 accttgggga caagctgcgc atgatcgtca tgggacacag aagagtccat atcagcagac
661 agctggaggt ggagcccgag gagccggagg cggagaacaa gcacaagccc cgcaggaagt
721 caaagcgggg caagaaggag gcggaggacg agctgagcgc caggcacccg gcggagctgg
781 cgatggagcc cacccctgag ctcccggctg aggtgctcat ggtggaggta gagaacgttg
841 tccacgagga cttccaggtc acggaggagg tgaaagccct gactgcagag atcgtgaaga
901 ccatccggga catcattgcc ttgaaccctc tctacaggga gtcagtgctg cagatgatgc
961 aggctggcca gcgggtggtg gacaacccca tctacctgag cgacatgggc gccgcgctca
1021 ccggggccga gtcccatgag ctgcaggacg tcctggaaga gaccaatatt cctaagcggc
1081 tgtacaaggc cctctccctg ctgaagaagg aatttgaact gagcaagctg cagcagcgcc
1141 tggggcggga ggtggaggag aagatcaagc agacccaccg taagtacctg ctgcaggagc
1201 agctaaagat catcaagaag gagctgggcc tggagaagga cgacaaggat gccatcgagg
1261 agaagttccg ggagcgcctg aaggagctcg tggtccccaa gcacgtcatg gatgttgtgg
1321 acgaggagct gagcaagctg ggcctgctgg acaaccactc ctcggagttc aatgtcaccc
1381 gcaactacct agactggctc acgtccatcc cttggggcaa gtacagcaac gagaacctgg
1441 acctggcgcg ggcacaggca gtgctggagg aagaccacta cggcatggag gacgtcaaga
1501 aacgcatcct ggagttcatt gccgttagcc agctccgcgg ctccacccag ggcaagatcc
1561 tctgcttcta tggcccccct ggcgtgggta agaccagcat tgctcgctcc atcgcccgcg
1621 ccctgaaccg agagtacttc cgcttcagcg tcgggggcat gactgacgtg gctgagatca
1681 agggccacag gcggacctac gtgggcgcca tgcccgggaa gatcatccag tgtttgaaga
1741 agaccaagac ggagaacccc ctgatcctca tcgacgaggt ggacaagatc ggccgaggct
1801 accaggggga cccgtcgtcg gcactgctgg agctgctgga cccagagcag aatgccaact
1861 tcctggacca ctacctggac gtgcccgtgg acttgtccaa ggtgctgttc atctgcacgg
1921 ccaacgtcac ggacaccatc cccgagccgc tgcgagaccg tatggagatg atcaacgtgt
1981 cgggctacgt ggcccaggag aagctggcca ttgcggagcg ctacctggtg ccccaggctc
2041 gcgccctgtg tggcttggat gagagcaagg ccaagctgtc atcggacgtg ctgacgctgc
2101 tcatcaagca gtactgccgc gagagcggtg tccgcaacct gcagaagcaa gtggagaagg
2161 tgttacggaa atcggcctac aagattgtca gcggcgaggc cgagtccgtg gaggtgacgc
2221 ccgagaacct gcaggacttc gtggggaagc ccgtgttcac cgtggagcgc atgtatgacg
2281 tgacaccgcc cggcgtggtc atggggctgg cctggaccgc aatgggaggc tccacgctgt
2341 ttgtggagac atccctgaga cggccacagg acaaggatgc caagggtgac aaggatggca
2401 gcctggaggt gacaggccag ctgggggagg tgatgaagga gagcgcccgc atagcctaca
2461 ccttcgccag agccttcctc atgcagcacg cccccgccaa tgactacctg gtgacctcac
2521 acatccacct gcatgtgccc gagggcgcca cccccaagga cggcccaagc gcaggctgca
2581 ccatcgtcac ggccctgctg tccctggcca tgggcaggcc tgtccggcag aatctggcca
2641 tgactggcga agtctccctc acgggcaaga tcctgcctgt tggtggcatc aaggagaaga
2701 ccattgcggc caagcgcgca ggggtgacgt gcatcgtcct gccagccgag aacaagaagg
2761 acttctacga cctggcagcc ttcatcaccg agggcctgga ggtgcacttc gtggaacact
2821 accgggagat cttcgacatc gccttcccgg acgagcaggc agaggcgctg gccgtggaac
2881 ggtgacggcc accccgggac tgcaggcggc ggatgtcagg ccctgtctgg gccagaactg
2941 agcgctgtgg ggagcgcgcc cggacctggc agtggagcca ccgagcgagc agctcggtcc
3001 agtgacccag atcccaggga cctcagtcgg cttaatcaga gtgtggcata gaagctattt
3061 aatgattaaa gtcatttgca gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3121 aaaaaaaaaa aaaaaaa
//