LOCUS BC000180 1411 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens keratin 18, mRNA (cDNA clone MGC:5055 IMAGE:2984862),
complete cds.
ACCESSION BC000180
VERSION BC000180.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1411)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1411)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Feb 23, 2001 this sequence version replaced BC000180.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 3 Row: b Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40354194.
FEATURES Location/Qualifiers
source 1..1411
/db_xref="H-InvDB:HIT000029411"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:5055 IMAGE:2984862"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1411
/gene="KRT18"
/gene_synonym="CYK18"
/gene_synonym="K18"
/db_xref="GeneID:3875"
/db_xref="HGNC:HGNC:6430"
/db_xref="MIM:148070"
CDS 42..1334
/gene="KRT18"
/gene_synonym="CYK18"
/gene_synonym="K18"
/codon_start=1
/product="keratin 18"
/protein_id="AAH00180.1"
/db_xref="GeneID:3875"
/db_xref="HGNC:HGNC:6430"
/db_xref="MIM:148070"
/translation="MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGS
RISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLE
TENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLA
ADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHE
EEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIE
ESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQ
MEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNL
GDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH"
BASE COUNT 367 a 388 c 421 g 235 t
ORIGIN
1 cgcaaagcct gagtcctgtc ctttctctct ccccggacag catgagcttc accactcgct
61 ccaccttctc caccaactac cggtccctgg gctctgtcca ggcgcccagc tacggcgccc
121 ggccggtcag cagcgcggcc agcgtctatg caggcgctgg gggctctggt tcccggatct
181 ccgtgtcccg ctccaccagc ttcaggggcg gcatggggtc cgggggcctg gccaccggga
241 tagccggggg tctggcagga atgggaggca tccagaacga gaaggagacc atgcaaagcc
301 tgaacgaccg cctggcctct tacctggaca gagtgaggag cctggagacc gagaaccgga
361 ggctggagag caaaatccgg gagcacttgg agaagaaggg accccaggtc agagactgga
421 gccattactt caagatcatc gaggacctga gggctcagat cttcgcaaat actgtggaca
481 atgcccgcat cgttctgcag attgacaatg cccgtcttgc tgctgatgac tttagagtca
541 agtatgagac agagctggcc atgcgccagt ctgtggagaa cgacatccat gggctccgca
601 aggtcattga tgacaccaat atcacacgac tgcagctgga gacagagatc gaggctctca
661 aggaggagct gctcttcatg aagaagaacc acgaagagga agtaaaaggc ctacaagccc
721 agattgccag ctctgggttg accgtggagg tagatgcccc caaatctcag gacctcgcca
781 agatcatggc agacatccgg gcccaatatg acgagctggc tcggaagaac cgagaggagc
841 tagacaagta ctggtctcag cagattgagg agagcaccac agtggtcacc acacagtctg
901 ctgaggttgg agctgctgag acgacgctca cagagctgag acgtacagtc cagtccttgg
961 agatcgacct ggactccatg agaaatctga aggccagctt ggagaacagc ctgagggagg
1021 tggaggcccg ctacgcccta cagatggagc agctcaacgg gatcctgctg caccttgagt
1081 cagagctggc acagacccgg gcagagggac agcgccaggc ccaggagtat gaggccctgc
1141 tgaacatcaa ggtcaagctg gaggctgaga tcgccaccta ccgccgcctg ctggaagatg
1201 gcgaggactt taatcttggt gatgccttgg acagcagcaa ctccatgcaa accatccaaa
1261 agaccaccac ccgccggata gtggatggca aagtggtgtc tgagaccaat gacaccaaag
1321 ttctgaggca ttaagccagc agaagcaggg taccctttgg ggagcaggag gccaataaaa
1381 agttcagagt tcaaaaaaaa aaaaaaaaaa a
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