LOCUS BC000126 1670 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens sirtuin (silent mating type information regulation 2
homolog) 5 (S. cerevisiae), mRNA (cDNA clone MGC:1103
IMAGE:3352592), complete cds.
ACCESSION BC000126
VERSION BC000126.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1670)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1670)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: a Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13787213.
FEATURES Location/Qualifiers
source 1..1670
/db_xref="H-InvDB:HIT000029366"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1103 IMAGE:3352592"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1670
/gene="SIRT5"
/gene_synonym="SIR2L5"
/db_xref="GeneID:23408"
/db_xref="HGNC:HGNC:14933"
/db_xref="MIM:604483"
CDS 297..1229
/gene="SIRT5"
/gene_synonym="SIR2L5"
/codon_start=1
/product="sirtuin (silent mating type information
regulation 2 homolog) 5 (S. cerevisiae)"
/protein_id="AAH00126.1"
/db_xref="GeneID:23408"
/db_xref="HGNC:HGNC:14933"
/db_xref="MIM:604483"
/translation="MRPLQIVPSRLISQLYCGLKPPASTRNQICLKMARPSSSMADFR
KFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPSRVWEFY
HYRREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAGTKNLLEIHGS
LFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGGLLRP
HVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNT
ETTPATNRFRFHFQGPCGTTLPEALACHENETVS"
BASE COUNT 474 a 365 c 431 g 400 t
ORIGIN
1 ccggagcgcg gtcgggacac agcgcctcta ggagaaagcc tggaaggcgc tccgggggta
61 cccagagctc ttagcgggcc ggcagcatgt gcggggccca agtaaatgga aatgttttct
121 aacatataaa aacctacaga agaagaaaat aattttctgg atcaaattag aagtctgtat
181 tatattgatg tctccagatt caaatatatt agaaagcagc cgtggagaca accatcttca
241 ttttgggaga aataactaaa gcccgcctca agcattagaa ctacagacaa accctgatgc
301 gacctctcca gattgtccca agtcgattga tttcccagct atattgtggc ctgaagcctc
361 cagcgtccac acgaaaccag atttgcctga aaatggctcg gccaagttca agtatggcag
421 attttcgaaa gttttttgca aaagcaaagc acatagtcat catctcagga gctggtgtta
481 gtgcagaaag tggtgttccg accttcagag gagctggagg ttattggaga aaatggcaag
541 cccaggacct ggcgactccc ctggcctttg cccacaaccc gtcccgggtg tgggagttct
601 accactaccg gcgggaggtc atggggagca aggagcccaa cgccgggcac cgcgccatag
661 ccgagtgtga gacccggctg ggcaagcagg gccggcgagt cgtggtcatc acccagaaca
721 tcgatgagct gcaccgcaag gctggcacca agaaccttct ggagatccat ggtagcttat
781 ttaaaactcg atgtacctct tgtggagttg tggctgagaa ttacaagagt ccaatttgtc
841 cagctttatc aggaaaaggt gctccagaac ctggaactca agatgccagc atcccagttg
901 agaaacttcc ccggtgtgaa gaggcaggct gcgggggctt gctgcgacct catgtcgtgt
961 ggtttggaga aaacctggat cctgccattc tggaggaggt tgacagagag ctcgcccact
1021 gtgatttatg tctagtggtg ggcacttcct ctgtggtgta cccagcagcc atgtttgccc
1081 cccaggtggc tgccaggggc gtgccagtgg ctgaatttaa cacggagacc accccagcta
1141 cgaacagatt caggtttcat ttccagggac cctgtggaac gactcttcct gaagcccttg
1201 cctgtcatga aaatgaaact gtttcttaag tgtcctgggg aagaaagaaa ttacagtata
1261 tctaagaact aggccacacg cagaggagaa atggtcttat gggtggtgag ctgagtactg
1321 aacaatctaa aaatagcctc tgattccctc gctggaatcc aacctgttga taagtgatgg
1381 gggtttagaa gtagcaaaga gcacccacat tcaaaagtca cagaactgga aagttaattc
1441 atattatttg gtttgaactg aaacgtgagg tatctttgat gtgtatggtt ggttattggg
1501 agggaaaaat tttgtaaatt agattgtcta aaaaaaatag ttattctgat tatatttttg
1561 ttatctgggc aaagtagaag tcaaggggta aaaaccctac tattctgatt tttgcacaag
1621 ttttagtgga aaataaaatc acactctaca gtaaaaaaaa aaaaaaaaaa
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