LOCUS BC000117 1676 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens GDP-mannose 4,6-dehydratase, mRNA (cDNA clone MGC:1739
IMAGE:3351070), complete cds.
ACCESSION BC000117
VERSION BC000117.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1676)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1676)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: k Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 41584204.
FEATURES Location/Qualifiers
source 1..1676
/db_xref="H-InvDB:HIT000029358"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1739 IMAGE:3351070"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1676
/gene="GMDS"
/gene_synonym="GMD"
/db_xref="GeneID:2762"
/db_xref="HGNC:HGNC:4369"
/db_xref="MIM:602884"
CDS 178..1296
/gene="GMDS"
/gene_synonym="GMD"
/codon_start=1
/product="GDP-mannose 4,6-dehydratase"
/protein_id="AAH00117.1"
/db_xref="GeneID:2762"
/db_xref="HGNC:HGNC:4369"
/db_xref="MIM:602884"
/translation="MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLL
EKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKP
TEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYG
KVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANF
VTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATG
EVHSVREFVEKSFLHIGKTIVWEGKNENEVGRCKETGKVHVTVDLKYYRPTEVDFLQG
DCTKAKQKLNWKPRVAFDELVREMVHADVELMRTNPNA"
BASE COUNT 393 a 446 c 466 g 371 t
ORIGIN
1 gcacggcctc ccgtgcgccc ctgtcagact gtggcggccg gtcgcgcggt gcgctctccc
61 tccctgcccg cagcctggag aggcgcttcg tgctgcacac ccccgcgttc ctgccggcac
121 cgcgcctgcc ctctgccgcg ctccgccctg ccgccgaccg cacgcccgcc gcgggacatg
181 gcacacgcac cggcacgctg ccccagcgcc cggggctccg gggacggcga gatgggcaag
241 cccaggaacg tggcgctcat caccggtatc acaggccagg atggttccta cctggctgag
301 ttcctgctgg agaaaggcta tgaggtccat ggaattgtac ggcggtccag ttcatttaat
361 acgggtcgaa ttgagcatct gtataagaat ccccaggctc acattgaagg aaacatgaag
421 ttgcactatg gcgatctcac tgacagtacc tgccttgtga agatcattaa tgaagtaaag
481 cccacagaga tctacaacct tggagcccag agccacgtca aaatttcctt tgacctcgct
541 gagtacactg cggacgttga cggagttggc actctacgac ttctagatgc agttaagact
601 tgtggcctta tcaactctgt gaagttctac caagcctcaa caagtgaact ttatgggaaa
661 gtgcaggaaa taccccagaa ggagaccacc cctttctatc cccggtcacc ctatggggca
721 gcaaaactct atgcctattg gattgtggtg aacttccgtg aggcgtataa tctctttgca
781 gtgaacggca ttctcttcaa tcatgagagt cccagaagag gagctaattt cgttactcga
841 aaaattagcc ggtcagtagc taagatttac cttggacaac tggaatgttt cagtttggga
901 aatctggatg ccaaacgaga ttggggccat gccaaggact atgtggaggc tatgtggttg
961 atgttgcaga atgacgagcc ggaggacttc gttatagcta ctggggaggt ccatagtgtc
1021 cgggaatttg tcgagaaatc attcttgcac attggaaaaa ccattgtgtg ggaaggaaag
1081 aatgaaaatg aagtgggcag atgtaaagag accggcaaag ttcacgtgac tgtggatctc
1141 aagtactacc ggccaactga agtggacttt ctgcagggcg actgcaccaa agcgaaacag
1201 aagctgaact ggaagccccg ggtcgctttc gatgagctgg tgagggagat ggtgcacgcc
1261 gacgtggagc tcatgaggac aaaccccaat gcctgagcag cgcctcggag cccggcccgc
1321 cctccggcta caatccccgc agagtctccg gtgcagacgc gctgcgggga tggggagcgg
1381 cgtgccaatc tgcgggtccc ctgcggcccc tgctgccgct gcgctgtccc ggccgcaaga
1441 gcggggccgc cccgccgagg tttgtagcag ccgggatgtg accctccagg gtttgggtcg
1501 ctttgcgttt gtcgaagcct cctctgaatg gctttgtgaa atcaagatgt tttaatcaca
1561 ttcactttac ttgaaattat gttgttacac aacaaattgt ggggccttca aattgttttt
1621 ctcttttcat attaaaaatg gtctttctgt gaactagcaa aaaaaaaaaa aaaaaa
//