LOCUS BC000096 1789 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens HtrA serine peptidase 2, mRNA (cDNA clone MGC:1083
IMAGE:3508944), complete cds.
ACCESSION BC000096
VERSION BC000096.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1789)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1789)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC000096.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: f Column: 10.
FEATURES Location/Qualifiers
source 1..1789
/db_xref="H-InvDB:HIT000029342"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1083 IMAGE:3508944"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1789
/gene="HTRA2"
/gene_synonym="OMI"
/db_xref="GeneID:27429"
/db_xref="HGNC:HGNC:14348"
/db_xref="MIM:606441"
CDS 29..1405
/gene="HTRA2"
/gene_synonym="OMI"
/codon_start=1
/product="HtrA serine peptidase 2"
/protein_id="AAH00096.1"
/db_xref="GeneID:27429"
/db_xref="HGNC:HGNC:14348"
/db_xref="MIM:606441"
/translation="MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTS
DPRARVTYGTPSLWARLSVGVTEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTR
SRAWLAVALGAGGAVLLLLWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPA
VVYIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEA
VVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVS
SAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIP
SDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILAELQLREPSFPDVQHGVL
IHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVRTQSQLAVQIRRGRETLTL
YVTPEVTE"
BASE COUNT 384 a 481 c 536 g 388 t
ORIGIN
1 gggcgaggag gcagccaagg cggagctgat ggctgcgccg agggcggggc ggggtgcagg
61 ctggagcctt cgggcatggc gggctttggg gggcattcgc tgggggagga gaccccgttt
121 gacccctgac ctccgggccc tgctgacgtc aggaacttct gacccccggg cccgagtgac
181 ttatgggacc cccagtctct gggcccggtt gtctgttggg gtcactgaac cccgagcatg
241 cctgacgtct gggaccccgg gtccccgggc acaactgact gcggtgaccc cagataccag
301 gacccgggag gcctcagaga actctggaac ccgttcgcgc gcgtggctgg cggtggcgct
361 gggcgctggg ggggcagtgc tgttgttgtt gtggggcggg ggtcggggtc ctccggccgt
421 cctcgccgcc gtccctagcc cgccgcccgc ttctccccgg agtcagtaca acttcatcgc
481 agatgtggtg gagaagacag cacctgccgt ggtctatatc gagatcctgg accggcaccc
541 tttcttgggc cgcgaggtcc ctatctcgaa cggctcagga ttcgtggtgg ctgccgatgg
601 gctcattgtc accaacgccc atgtggtggc tgatcggcgc agagtccgtg tgagactgct
661 aagcggcgac acgtatgagg ccgtggtcac agctgtggat cccgtggcag acatcgcaac
721 gctgaggatt cagactaagg agcctctccc cacgctgcct ctgggacgct cagctgatgt
781 ccggcaaggg gagtttgttg ttgccatggg aagtcccttt gcactgcaga acacgatcac
841 atccggcatt gttagctctg ctcagcgtcc agccagagac ctgggactcc cccaaaccaa
901 tgtggaatac attcaaactg atgcagctat tgattttgga aactctggag gtcccctggt
961 taacctggat ggggaggtga ttggagtgaa caccatgaag gtcacagctg gaatctcctt
1021 tgccatccct tctgatcgtc ttcgagagtt tctgcatcgt ggggaaaaga agaattcctc
1081 ctccggaatc agtgggtccc agcggcgcta cattggggtg atgatgctga ccctgagtcc
1141 cagcatcctt gctgaactac agcttcgaga accaagcttt cccgatgttc agcatggtgt
1201 actcatccat aaagtcatcc tgggctcccc tgcacaccgg gctggtctgc ggcctggtga
1261 tgtgattttg gccattgggg agcagatggt acaaaatgct gaagatgttt atgaagctgt
1321 tcgaacccaa tcccagttgg cagtgcagat ccggcgggga cgagaaacac tgaccttata
1381 tgtgacccct gaggtcacag aatgaataga tcaccaagag tatgaggctc ctgctctgat
1441 ttcctccttg cctttctggc tgaggttctg agggcaccga gacagagggt taaatgaacc
1501 agtgggggca ggtccctcca accaccagca ctgactcctg ggctctgaag aatcacagaa
1561 acacttttta tataaaataa aattatacct agcaacatat tatagtaaaa aatgaggtgg
1621 gagggctgga tcttttcccc caccaaaagg ctagaggtaa agctgtatcc ccctaaactt
1681 aggggagata ctggagctga ccatcctgac ctcctattaa agaaaatgag ctgctgccat
1741 cttttgtggg cagttagtca ggtgctgcaa aaaaaaaaaa aaaaaaaaa
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