LOCUS BC000094 1798 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 2,
mRNA (cDNA clone MGC:1848 IMAGE:3508140), complete cds.
ACCESSION BC000094
VERSION BC000094.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1798)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1798)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC000094.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: h Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 55953116.
FEATURES Location/Qualifiers
source 1..1798
/db_xref="H-InvDB:HIT000029340"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1848 IMAGE:3508140"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1798
/gene="RPS6KB2"
/gene_synonym="KLS"
/gene_synonym="p70(S6K)-beta"
/gene_synonym="P70-beta"
/gene_synonym="P70-beta-1"
/gene_synonym="P70-beta-2"
/gene_synonym="p70S6Kb"
/gene_synonym="S6K-beta2"
/gene_synonym="S6K2"
/gene_synonym="SRK"
/gene_synonym="STK14B"
/db_xref="GeneID:6199"
/db_xref="HGNC:HGNC:10437"
/db_xref="MIM:608939"
CDS 56..1504
/gene="RPS6KB2"
/gene_synonym="KLS"
/gene_synonym="p70(S6K)-beta"
/gene_synonym="P70-beta"
/gene_synonym="P70-beta-1"
/gene_synonym="P70-beta-2"
/gene_synonym="p70S6Kb"
/gene_synonym="S6K-beta2"
/gene_synonym="S6K2"
/gene_synonym="SRK"
/gene_synonym="STK14B"
/codon_start=1
/product="ribosomal protein S6 kinase, 70kDa, polypeptide
2"
/protein_id="AAH00094.3"
/db_xref="GeneID:6199"
/db_xref="HGNC:HGNC:10437"
/db_xref="MIM:608939"
/translation="MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGH
YEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLR
KAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHL
EREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKE
SIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKK
TMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWD
DLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAP
SVLDSIKEGFSFQPKLRSPRRLNSSPRVPVSPLKFSPFEGFRPSPSLPEPTELPLPPL
LPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR"
BASE COUNT 403 a 538 c 540 g 317 t
ORIGIN
1 gtcagtcagt gcgcggccag gtacgggccg acgggcccgc ggggccggcg ccgccatggc
61 ggccgtgttt gatttggatt tggagacgga ggaaggcagc gagggcgagg gcgagccaga
121 gctcagcccc gcggacgcat gtccccttgc cgagttgagg gcagctggcc tagagcctgt
181 gggacactat gaagaggtgg agctgactga gaccagcgtg aacgttggcc cagagcgcat
241 cgggccccac tgctttgagc tgctgcgtgt gctgggcaag gggggctatg gcaaggtgtt
301 ccaggtgcga aaggtgcaag gcaccaactt gggcaaaata tatgccatga aagtcctaag
361 gaaggccaaa attgtgcgca atgccaagga cacagcacac acacgggctg agcggaacat
421 tctagagtca gtgaagcacc cctttattgt ggaactggcc tatgccttcc agactggtgg
481 caaactctac ctcatccttg agtgcctcag tggtggcgag ctcttcacgc atctggagcg
541 agagggcatc ttcctggaag atacggcctg cttctacctg gctgagatca cgctggccct
601 gggccatctc cactcccagg gcatcatcta ccgggacctc aagcccgaga acatcatgct
661 cagcagccag ggccacatca aactgaccga ctttggactc tgcaaggagt ctatccatga
721 gggcgccgtc actcacacct tctgcggcac cattgagtac atggcccctg agattctggt
781 gcgcagtggc cacaaccggg ctgtggactg gtggagcctg ggggccctga tgtacgacat
841 gctcactgga tcgccgccct ttaccgcaga gaaccggaag aaaaccatgg ataagatcat
901 caggggcaag ctggcactgc ccccctacct caccccagat gcccgggacc ttgtcaaaaa
961 gtttctgaaa cggaatccca gccagcggat tgggggtggc ccaggggatg ctgctgatgt
1021 gcagagacat ccctttttcc ggcacatgaa ttgggacgac cttctggcct ggcgtgtgga
1081 cccccctttc aggccctgtc tgcagtcaga ggaggacgtg agccagtttg atacccgctt
1141 cacacggcag acgccggtgg acagtcctga tgacacagcc ctcagcgaga gtgccaacca
1201 ggccttcctg ggcttcacat acgtggcgcc gtctgtcctg gacagcatca aggagggctt
1261 ctccttccag cccaagctgc gctcacccag gcgcctcaac agtagccccc gggtccccgt
1321 cagccccctc aagttctccc cttttgaggg gtttcggccc agccccagcc tgccggagcc
1381 cacggagcta cctctacctc cactcctgcc accgccgccg ccctcgacca ccgcccctct
1441 ccccatccgt cccccctcag ggaccaagaa gtccaagagg ggccgtgggc gtccagggcg
1501 ctaggaagcc gggtgggggt gagggtagcc cttgagccct gtccctgcgg ctgtgagagc
1561 agcaggaccc tgggccagtt ccagagacct gggggtgtgt ctgggggtgg ggtgtgagtg
1621 cgtatgaaag tgtgtgtctg ctggggcagc tgtgcccctg aatcatgggc acggagggcc
1681 gcccgccaca ccccgcgctc aactgctccc gtggaagatt aaagggctga atcatgaaaa
1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//