LOCUS BC000038 1576 bp mRNA linear HUM 19-JUN-2006
DEFINITION Homo sapiens sphingomyelin phosphodiesterase 2, neutral membrane
(neutral sphingomyelinase), mRNA (cDNA clone MGC:1617
IMAGE:3509845), complete cds.
ACCESSION BC000038
VERSION BC000038.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1576)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1576)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC000038.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: j Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4507094.
FEATURES Location/Qualifiers
source 1..1576
/db_xref="H-InvDB:HIT000029300"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1617 IMAGE:3509845"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1576
/gene="SMPD2"
/gene_synonym="NSMASE"
/db_xref="GeneID:6610"
/db_xref="HGNC:HGNC:11121"
/db_xref="MIM:603498"
CDS 267..1538
/gene="SMPD2"
/gene_synonym="NSMASE"
/codon_start=1
/product="sphingomyelin phosphodiesterase 2, neutral
membrane (neutral sphingomyelinase)"
/protein_id="AAH00038.1"
/db_xref="GeneID:6610"
/db_xref="HGNC:HGNC:11121"
/db_xref="MIM:603498"
/translation="MKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDL
ALLEEVWSEQDFQYLRQKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNG
YPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELA
QFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTMVP
KNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSFETTTGFDPHSGTPLSDHEALM
ATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGLGMAQARWWATFASYVIGLG
LLLLALLCVLAAGGGAGEAAILLWTPSVGLVLWAGAFYLFHVQEVNGLYRAQAELQHV
LGRAREAQDLGPEPQPALLLGQQEGDRTKEQ"
BASE COUNT 337 a 462 c 464 g 313 t
ORIGIN
1 ggcccttacc gagcctgggc gcccggattt cggcagcgga tcgcctttcc gggttggcgg
61 cccgcctgat tgggaacagc cggccggttg ccgggggaac gcgggagtcg ggcccgacct
121 gagccacgcg ggcttggtgc ccacctgtgc gcgccgcctg cgaagaagga acggtctagg
181 gagaaggcgc cgccggccgc ccccgtcccc accgcggccg tcgctggaga gttcgagccg
241 cctagcgccc ctggagctcc ccaaccatga agcccaactt ctccctgcga ctgcggatct
301 tcaacctcaa ctgctggggc attccgtact tgagcaagca ccgggccgac cgcatgaggc
361 gcctgggaga ctttctgaac caggagagct tcgacctggc tttgctggag gaggtgtgga
421 gtgagcagga cttccagtac ctgagacaga agctgtcacc tacctaccca gctgcacacc
481 acttccggag cggaatcatt ggcagtggcc tctgtgtctt ctccaaacat ccaatccagg
541 agcttaccca gcacatctac actctcaatg gctaccccta catgatccat catggtgact
601 ggttcagtgg gaaggctgtg gggctgctgg tgctccatct aagtggcatg gtgctcaacg
661 cctatgtgac ccatctccat gccgaataca atcgacagaa ggacatctac ctagcacatc
721 gtgtggccca agcttgggaa ttggcccagt tcatccacca cacatccaag aaggcagacg
781 tggttctgtt gtgtggagac ctcaacatgc acccagaaga cctgggctgc tgcctgctga
841 aggagtggac agggcttcat gatgcctatc ttgaaactcg ggacttcaag ggctctgagg
901 aaggcaacac aatggtaccc aagaactgct acgtcagcca gcaggagctg aagccatttc
961 cctttggtgt ccgcattgac tacgtgcttt acaaggcagt ttctgggttt tacatctcct
1021 gtaagagttt tgaaaccact acaggctttg accctcacag tggcaccccc ctctctgatc
1081 atgaagccct gatggctact ctgtttgtga ggcacagccc cccacagcag aaccccagct
1141 ctacccacgg accagcagag aggtcgccgt tgatgtgtgt gctaaaggag gcctggacgg
1201 agctgggtct gggcatggct caggctcgct ggtgggccac cttcgctagc tatgtgattg
1261 gcctggggct gcttctcctg gcactgctgt gtgtcctggc ggctggagga ggggccgggg
1321 aagctgccat actgctctgg acccccagtg tagggctggt gctgtgggca ggtgcattct
1381 acctcttcca cgtacaggag gtcaatggct tatatagggc ccaggctgag ctccagcatg
1441 tgctaggaag ggcaagggag gcccaggatc tgggcccaga gcctcagcca gccctactcc
1501 tggggcagca ggagggggac agaactaaag aacaataaag cttggccctt taaaaaaaaa
1561 aaaaaaaaaa aaaaaa
//