LOCUS BC000011 1865 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens mevalonate (diphospho) decarboxylase, mRNA (cDNA clone
MGC:1701 IMAGE:3505156), complete cds.
ACCESSION BC000011
VERSION BC000011.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1865)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1865)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC000011.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: d Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4505288.
FEATURES Location/Qualifiers
source 1..1865
/db_xref="H-InvDB:HIT000029279"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1701 IMAGE:3505156"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1865
/gene="MVD"
/gene_synonym="FP17780"
/gene_synonym="MPD"
/db_xref="GeneID:4597"
/db_xref="HGNC:HGNC:7529"
/db_xref="MIM:603236"
CDS 31..1233
/gene="MVD"
/gene_synonym="FP17780"
/gene_synonym="MPD"
/codon_start=1
/product="mevalonate (diphospho) decarboxylase"
/protein_id="AAH00011.1"
/db_xref="GeneID:4597"
/db_xref="HGNC:HGNC:7529"
/db_xref="MIM:603236"
/translation="MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLH
QDQLKTTTTAVISKDFTEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPL
PSSLSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSAC
RSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRAS
VETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISY
LNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGS
NGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGP
DGLPKPAA"
BASE COUNT 360 a 568 c 621 g 316 t
ORIGIN
1 gtggagctgg ggtcactgcg cggtgggacc atggcctcgg agaagccgct ggcggcagtc
61 acttgtacag cgccggtcaa catcgcggtc atcaagtact ggggcaagcg cgatgaagag
121 ctggttctgc ccatcaactc ctccctgagc gtcactctgc accaggacca gttaaaaacc
181 accacaacag ccgtcatcag caaggacttc accgaggacc ggatttggct gaatggccgg
241 gaggaggatg tggggcagcc gaggctgcag gcctgcctgc gggagatccg ctgcctggcc
301 cggaagcgga ggaactcacg ggatggggac ccgctgccct ccagcctcag ctgcaaggtg
361 cacgtggcat cggtgaacaa cttccccacg gctgcgggcc tggcctcctc agcggcgggc
421 tatgcctgcc tagcctacac cctggcccgt gtctacggcg tggagagtga cctctcagaa
481 gtggctcgcc ggggctcagg cagcgcctgc cggagcctgt atgggggctt tgtggagtgg
541 cagatgggag agcaggccga cgggaaggac agcatcgctc ggcaagtggc ccccgagtca
601 cactggcctg aactccgcgt gctcatcctt gtggtgagcg ctgagaagaa gctgacaggc
661 agtaccgtgg gcatgcgggc cagtgtggag accagccccc tgcttcggtt ccgggccgag
721 tccgtggtgc ccgcgcgcat ggcggagatg gcccgctgca tccgggagcg agacttcccc
781 agcttcgccc agctgaccat gaaggacagc aaccagttcc acgccacctg cctcgacacc
841 ttcccgccca tctcttacct caatgccatc tcctggcgca tcatccacct ggtgcaccgc
901 ttcaacgccc accacgggga caccaaggtg gcgtacacct ttgacgcggg ccccaatgcc
961 gtgatcttca ccctggacga cactgtggct gagtttgtgg ctgctgtgtg gcacggcttt
1021 cccccaggct cgaatggaga cacgtttctg aaggggctgc aggtgaggcc ggcccctctc
1081 tcagctgagc ttcaggctgc gctggccatg gagccgaccc ccggtggggt caaatacatc
1141 attgtcactc aggtggggcc agggcctcaa atcctggatg acccctgcgc ccacctcctg
1201 ggtcctgacg gcctgccgaa gccagctgcc tgactgcctc agcagggacc gcatgccgct
1261 tggagaaggg gtggcctcgc cggagctagg gagcggatgt ggtgggctgg ccggactcct
1321 gggacatgtg ggtggtggct tgaccccggg cccatgggca gcttgctgtg gggcagtgca
1381 gggagtcctg cggccgccca ggtgtcagga gaggtccccg ccgagtgctt cagctgccct
1441 aagctgcacc agcgctttgc caagatggga tggggagggg gtatgagaac tggcagagcc
1501 tcggtgcagc agggctgaag ggctttctca ccccagctct ggctatgccc agttctctga
1561 gaaaggagct cagtggggag gtggtccctc cagcggacca gggaaggggt cactgtgctg
1621 ggagcagcct ccttgggcct caggaaacca ccaagtgcct cggatggtgg ctgcccacgg
1681 cgcttctgct gagaccctgc ccccggccca ggtgtctcgg agggtggctg cccacggcct
1741 gggtgtggct ggaatggtgg caggagtggg caccagtgcg gccccggtgg ccatggggaa
1801 taaaccagca ttactgccaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1861 aaaaa
//