LOCUS MT558686 29895 bp RNA linear VRL 03-JUN-2020 DEFINITION Severe acute respiratory syndrome coronavirus 2 isolate SARS-CoV-2/human/USA/VA-DCLS-0262/2020, complete genome. ACCESSION MT558686 VERSION MT558686.1 KEYWORDS . SOURCE Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORGANISM Severe acute respiratory syndrome coronavirus 2 Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus. REFERENCE 1 (bases 1 to 29895) AUTHORS Fink,L. TITLE Direct Submission JOURNAL Submitted (27-MAY-2020) Department of General Services Division of Consolidated Laboratory Services, Virginia Division of Consolidated Laboratory Services Sequencing Submission Group, 500 North 5th Street, Richmond, VA 23219, USA COMMENT ##Assembly-Data-START## Assembly Method :: minimap2 v. 2.17; ivar v. 1.1 Sequencing Technology :: Illumina ##Assembly-Data-END## FEATURES Location/Qualifiers source 1..29895 /organism="Severe acute respiratory syndrome coronavirus 2" /mol_type="genomic RNA" /isolate="SARS-CoV-2/human/USA/VA-DCLS-0262/2020" /host="Homo sapiens" /db_xref="taxon:2697049" /country="USA: Virginia" /collection_date="2020-04" gene 258..21547 /gene="ORF1ab" CDS join(258..13460,13460..21547) /gene="ORF1ab" /ribosomal_slippage /codon_start=1 /product="ORF1ab polyprotein" /protein_id="QKG81785.1" /translation="MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQ HLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGE TLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQ LDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFP LNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTG DFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESG LKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNL LEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN FKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAA ITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKL KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLV NKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEII FLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK YCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEK CSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEF KLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPE EEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSG YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD DYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLA PLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIA EIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGN LHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREM LAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLIN TLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVIT FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPH NSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG DVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQ IPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSK ETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYY KKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVT FFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWST KPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGD IILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRI KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTA ALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLET IQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWL MWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE CTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRP INPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPI NVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVN TFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVEC LKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALI WNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWL KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFA NKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLP RVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVA YESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSG RWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTN DVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVN VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV LDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHW LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFL LPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTAR TVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLAR GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYL VSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK SEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN NIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDA DSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH PNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA DAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKD EDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQR LTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA NLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVV DSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQ TYHPNCVNCLDDRCILHCANFNVLFSTVFPLTSFGPLVRKIFVDGVPFVVSTGYHFRE LGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDI RQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT RGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLAR KHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMM ILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCS QHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKH PNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTV LQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCD VTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDW TNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKP RPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGK SHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQ LPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK AHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNA VASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSD RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEG CHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIP LMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNA HVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCL FWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQ LPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYN MMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNT VYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEG SVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFK PRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESP FELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV TIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGD SATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLP TGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEG FFTYICGFIQQRLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFL IGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE GQINDMILSLLSKGRLIIRENNRVVISSDVLVNN" mat_peptide 258..797 /gene="ORF1ab" /product="leader protein" mat_peptide 798..2711 /gene="ORF1ab" /product="nsp2" mat_peptide 2712..8546 /gene="ORF1ab" /product="nsp3" mat_peptide 8547..10046 /gene="ORF1ab" /product="nsp4" mat_peptide 10047..10964 /gene="ORF1ab" /product="3C-like proteinase" mat_peptide 10965..11834 /gene="ORF1ab" /product="nsp6" mat_peptide 11835..12083 /gene="ORF1ab" /product="nsp7" mat_peptide 12084..12677 /gene="ORF1ab" /product="nsp8" mat_peptide 12678..13016 /gene="ORF1ab" /product="nsp9" mat_peptide 13017..13433 /gene="ORF1ab" /product="nsp10" mat_peptide join(13434..13460,13460..16228) /gene="ORF1ab" /product="RNA-dependent RNA polymerase" mat_peptide 16229..18031 /gene="ORF1ab" /product="helicase" mat_peptide 18032..19612 /gene="ORF1ab" /product="3'-to-5' exonuclease" mat_peptide 19613..20650 /gene="ORF1ab" /product="endoRNAse" mat_peptide 20651..21544 /gene="ORF1ab" /product="2'-O-ribose methyltransferase" CDS 258..13475 /gene="ORF1ab" /codon_start=1 /product="ORF1a polyprotein" /protein_id="QKG81786.1" /translation="MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQ HLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGE TLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQ LDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFP LNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTG DFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESG LKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNL LEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN FKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAA ITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKL KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLV NKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEII FLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK YCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEK CSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEF KLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPE EEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSG YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD DYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLA PLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIA EIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGN LHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREM LAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLIN TLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVIT FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPH NSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG DVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQ IPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSK ETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYY KKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVT FFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWST KPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGD IILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRI KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTA ALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLET IQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWL MWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE CTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRP INPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPI NVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVN TFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVEC LKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALI WNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWL KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFA NKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLP RVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVA YESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSG RWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTN DVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVN VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV LDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHW LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFL LPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTAR TVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLAR GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYL VSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK SEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN NIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDA DSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH PNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA DAQSFLNGFAV" mat_peptide 258..797 /gene="ORF1ab" /product="leader protein" mat_peptide 798..2711 /gene="ORF1ab" /product="nsp2" mat_peptide 2712..8546 /gene="ORF1ab" /product="nsp3" mat_peptide 8547..10046 /gene="ORF1ab" /product="nsp4" mat_peptide 10047..10964 /gene="ORF1ab" /product="3C-like proteinase" mat_peptide 10965..11834 /gene="ORF1ab" /product="nsp6" mat_peptide 11835..12083 /gene="ORF1ab" /product="nsp7" mat_peptide 12084..12677 /gene="ORF1ab" /product="nsp8" mat_peptide 12678..13016 /gene="ORF1ab" /product="nsp9" mat_peptide 13017..13433 /gene="ORF1ab" /product="nsp10" mat_peptide 13434..13472 /gene="ORF1ab" /product="nsp11" stem_loop 13468..13495 /gene="ORF1ab" /note="Coronavirus frameshifting stimulation element stem-loop 1" stem_loop 13480..13534 /gene="ORF1ab" /note="Coronavirus frameshifting stimulation element stem-loop 2" gene 21555..25376 /gene="S" CDS 21555..25376 /gene="S" /codon_start=1 /product="surface glycoprotein" /protein_id="QKG81787.1" /translation="MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFR SSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIR GWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQ GFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFL LKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITN LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCF TNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYN YLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPY RVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFG RDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAI HADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPR RARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTM YICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFG GFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFN GLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQN VLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGA ISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMS ECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAH FPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELD SFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG KYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSE PVLKGVKLHYT" gene 25385..26212 /gene="ORF3a" CDS 25385..26212 /gene="ORF3a" /codon_start=1 /product="ORF3a protein" /protein_id="QKG81788.1" /translation="MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFG WLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLE APFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPY NSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQ LSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL" gene 26237..26464 /gene="E" CDS 26237..26464 /gene="E" /codon_start=1 /product="envelope protein" /protein_id="QKG81789.1" /translation="MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCC NIVNVSLVKPSFYVYSRVKNLNSSRVPDLLV" gene 26515..27183 /gene="M" CDS 26515..27183 /gene="M" /codon_start=1 /product="membrane glycoprotein" /protein_id="QKG81790.1" /translation="MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNR FLYIIKLIFLWLLWPVTLACFVLAAVYRINWITGGIAIAMACLVGLMWLSYFIASFRL FARTRSMWSFNPETNILLNVPLHGTILTRPLLESELVIGAVILRGHLRIAGHHLGRCD IKDLPKEITVATSRTLSYYKLGASQRVAGDSGFAAYSRYRIGNYKLNTDHSSSSDNIA LLVQ" gene 27194..27379 /gene="ORF6" CDS 27194..27379 /gene="ORF6" /codon_start=1 /product="ORF6 protein" /protein_id="QKG81791.1" /translation="MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSL TENKYSQLDEEQPMEID" gene 27386..27751 /gene="ORF7a" CDS 27386..27751 /gene="ORF7a" /codon_start=1 /product="ORF7a protein" /protein_id="QKG81792.1" /translation="MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNS PFHPLADNKFALTCFSTQFAFACPDGVKHVYQLRARSVSPKLFIRQEEVQELYSPIFL IVAAIVFITLCFTLKRKTE" gene 27748..27879 /gene="ORF7b" CDS 27748..27879 /gene="ORF7b" /codon_start=1 /product="ORF7b" /protein_id="QKG81793.1" /translation="MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA" gene 27886..28251 /gene="ORF8" CDS 27886..28251 /gene="ORF8" /codon_start=1 /product="ORF8 protein" /protein_id="QKG81794.1" /translation="MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSK WYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRC SFYEDFLEYHDVRVVLDFI" gene 28266..29525 /gene="N" CDS 28266..29525 /gene="N" /codon_start=1 /product="nucleocapsid phosphoprotein" /protein_id="QKG81795.1" /translation="MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQG LPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMK DLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQ LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAA LALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGR RGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYT GAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTV TLLPAADLDDFSKQLQQSMSSADSTQA" gene 29550..29666 /gene="ORF10" CDS 29550..29666 /gene="ORF10" /codon_start=1 /product="ORF10 protein" /protein_id="QKG81796.1" /translation="MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFNLT" stem_loop 29601..29636 /gene="ORF10" /note="Coronavirus 3' UTR pseudoknot stem-loop 1" stem_loop 29621..29649 /gene="ORF10" /note="Coronavirus 3' UTR pseudoknot stem-loop 2" stem_loop 29720..29760 /note="Coronavirus 3' stem-loop II-like motif (s2m)" BASE COUNT 8948 a 5487 c 5863 g 9597 t ORIGIN 1 tttatacctt cccaggtaac aaaccaacca actttcgatc tcttgtagat ctgttctcta 61 aacgaacttt aaaatctgtg tggctgtcac tcggctgcat gcttagtgca ctcacgcagt 121 ataattaata actaattact gtcgttgaca ggacacgagt aactcgtcta tcttctgcag 181 gctgcttacg gtttcgtccg tgttgcagcc gatcatcagc acatctaggt tttgtccggg 241 tgtgaccgaa aggtaagatg gagagccttg tccctggttt caacgagaaa acacacgtcc 301 aactcagttt gcctgtttta caggttcgcg acgtgctcgt acgtggcttt ggagactccg 361 tggaggaggt cttatcagag gcacgtcaac atcttaaaga tggcacttgt ggcttagtag 421 aagttgaaaa aggcgttttg cctcaacttg aacagcccta tgtgttcatc aaacgttcgg 481 atgctcgaac tgcacctcat ggtcatgtta tggttgagct ggtagcagaa ctcgaaggca 541 ttcagtacgg tcgtagtggt gagacacttg gtgtccttgt ccctcatgtg ggcgaaatac 601 cagtggctta ccgcaaggtt cttcttcgta agaacggtaa taaaggagct ggtggccata 661 gttacggcgc cgatctaaag tcatttgact taggcgacga gcttggcact gatccttatg 721 aagattttca agaaaactgg aacactaaac atagcagtgg tgttacccgt gaactcatgc 781 gtgagcttaa cggaggggca tacactcgct atgtcgataa caacttctgt ggccctgatg 841 gctaccctct tgagtgcatt aaagaccttc tagcacgtgc tggtaaagct tcatgcactt 901 tgtccgaaca actggacttt attgacacta agaggggtgt atactgctgc cgtgaacatg 961 agcatgaaat tgcttggtac acggaacgtt ctgaaaagag ctatgaattg cagacacctt 1021 ttgaaattaa attggcaaag aaatttgaca ccttcaatgg ggaatgtcca aattttgtat 1081 ttcccttaaa ttccataatc aagactattc aaccaagggt tgaaaagaaa aagcttgatg 1141 gctttatggg tagaattcga tctgtctatc cagttgcgtc accaaatgaa tgcaaccaaa 1201 tgtgcctttc aactctcatg aagtgtgatc attgtggtga aacttcatgg cagacgggcg 1261 attttgttaa agccacttgc gaattttgtg gcactgagaa tttgactaaa gaaggtgcca 1321 ctacttgtgg ttacttaccc caaaatgctg ttgttaaaat ttattgtcca gcatgtcaca 1381 attcagaagt aggacctgag catagtcttg ccgaatacca taatgaatct ggcttgaaaa 1441 ccattcttcg taagggtggt cgcactattg cctttggagg ctgtgtgttc tcttatgttg 1501 gttgccataa caagtgtgcc tattgggttc cacgtgctag cgctaacata ggttgtaacc 1561 atacaggtgt tgttggagaa ggttccgaag gtcttaatga caaccttctt gaaatactcc 1621 aaaaagagaa agtcaacatc aatattgttg gtgactttaa acttaatgaa gagatcgcca 1681 ttattttggc atctttttct gcttccacaa gtgcttttgt ggaaactgtg aaaggtttgg 1741 attataaagc attcaaacaa attgttgaat cctgtggtaa ttttaaagtt acaaaaggaa 1801 aagctaaaaa aggtgcctgg aatattggtg aacagaaatc aatactgagt cctctttatg 1861 catttgcatc agaggctgct cgtgttgtac gatcaatttt ctcccgcact cttgaaactg 1921 ctcaaaattc tgtgcgtgtt ttacagaagg ccgctataac aatactagat ggaatttcac 1981 agtattcact gagactcatt gatgctatga tgttcacatc tgatttggct actaacaatc 2041 tagttgtaat ggcctacatt acaggtggtg ttgttcagtt gacttcgcag tggctaacta 2101 acatctttgg cactgtttat gaaaaactca aacccgtcct tgattggctt gaagagaagt 2161 ttaaggaagg tgtagagttt cttagagacg gttgggaaat tgttaaattt atctcaacct 2221 gtgcttgtga aattgtcggt ggacaaattg tcacctgtgc aaaggaaatt aaggagagtg 2281 ttcagacatt ctttaagctt gtaaataaat ttttggcttt gtgtgctgac tctatcatta 2341 ttggtggagc taaacttaaa gccttgaatt taggtgaaac atttgtcacg cactcaaagg 2401 gattgtacag aaagtgtgtt aaatccagag aagaaactgg cctactcatg cctctaaaag 2461 ccccaaaaga aattatcttc ttagagggag aaacacttcc cacagaagtg ttaacagagg 2521 aagttgtctt gaaaactggt gatttacaac cattagaaca acctactagt gaagctgttg 2581 aagctccatt ggttggtaca ccagtttgta ttaacgggct tatgttgctc gaaatcaaag 2641 acacagaaaa gtactgtgcc cttgcaccta atatgatggt aacaaacaat accttcacac 2701 tcaaaggcgg tgcaccaaca aaggttactt ttggtgatga cactgtgata gaagtgcaag 2761 gttacaagag tgtgaatatc acttttgaac ttgatgaaag gattgataaa gtacttaatg 2821 agaagtgctc tgcctataca gttgaactcg gtacagaagt aaatgagttc gcctgtgttg 2881 tggcagatgc tgtcataaaa actttgcaac cagtatctga attacttaca ccactgggca 2941 ttgatttaga tgagtggagt atggctacat actacttatt tgatgagtct ggtgagttta 3001 aattggcttc acatatgtat tgttcttttt accctccaga tgaggatgaa gaagaaggtg 3061 attgtgaaga agaagagttt gagccatcaa ctcaatatga gtatggtact gaagatgatt 3121 accaaggtaa acctttggaa tttggtgcca cttctgctgc tcttcaacct gaagaagagc 3181 aagaagaaga ttggttagat gatgatagtc aacaaactgt tggtcaacaa gacggcagtg 3241 aggacaatca gacaactact attcaaacaa ttgttgaggt tcaacctcaa ttagagatgg 3301 aacttacacc agttgttcag actattgaag tgaatagttt tagtggttat ttaaaactta 3361 ctgacaatgt atacattaaa aatgcagaca ttgtggaaga agctaaaaag gtaaaaccaa 3421 cagtggttgt taatgcagcc aatgtttacc ttaaacatgg aggaggtgtt gcaggagcct 3481 taaataaggc tactaacaat gccatgcaag ttgaatctga tgattacata gctactaatg 3541 gaccacttaa agtgggtggt agttgtgttt taagcggaca caatcttgct aaacactgtc 3601 ttcatgttgt cggcccaaat gttaacaaag gtgaagacat tcaacttctt aagagtgctt 3661 atgaaaattt taatcagcac gaagttctac ttgcaccatt attatcagct ggtatttttg 3721 gtgctgaccc tatacattct ttaagagttt gtgtagatac tgttcgcaca aatgtctact 3781 tagctgtctt tgataaaaat ctctatgaca aacttgtttc aagctttttg gaaatgaaga 3841 gtgaaaagca agttgaacaa aagatcgctg agattcctaa agaggaagtt aagccattta 3901 taactgaaag taaaccttca gttgaacaga gaaaacaaga tgataagaaa atcaaagctt 3961 gtgttgaaga agttacaaca actctggaag aaactaagtt cctcacagaa aacttgttac 4021 tttatattga cattaatggc aatcttcatc cagattctgc cactcttgtt agtgacattg 4081 acatcacttt cttaaagaaa gatgctccat atatagtggg tgatgttgtt caagagggtg 4141 ttttaactgc tgtggttata cctactaaaa aggctggtgg cactactgaa atgctagcga 4201 aagctttgag aaaagtgcca acagacaatt atataaccac ttacccgggt cagggtttaa 4261 atggttacac tgtagaggag gcaaagacag tgcttaaaaa gtgtaaaagt gccttttaca 4321 ttctaccatc tattatctct aatgagaagc aagaaattct tggaactgtt tcttggaatt 4381 tgcgagaaat gcttgcacat gcagaagaaa cacgcaaatt aatgcctgtc tgtgtggaaa 4441 ctaaagccat agtttcaact atacagcgta aatataaggg tattaaaata caagagggtg 4501 tggttgatta tggtgctaga ttttactttt acaccagtaa aacaactgta gcgtcactta 4561 tcaacacact taacgatcta aatgaaactc ttgttacaat gccacttggc tatgtaacac 4621 atggcttaaa tttggaagaa gctgctcggt atatgagatc tctcaaagtg ccagctacag 4681 tttctgtttc ttcacctgat gctgttacag cgtataatgg ttatcttact tcttcttcta 4741 aaacacctga agaacatttt attgaaacca tctcacttgc tggttcctat aaagattggt 4801 cctattctgg acaatctaca caactaggta tagaatttct taagagaggt gataaaagtg 4861 tatattacac tagtaatcct accacattcc acctagatgg tgaagttatc acctttgaca 4921 atcttaagac acttctttct ttgagagaag tgaggactat taaggtgttt acaacagtag 4981 acaacattaa cctccacacg caagttgtgg acatgtcaat gacatatgga caacagtttg 5041 gtccaactta tttggatgga gctgatgtta ctaaaataaa acctcataat tcacatgaag 5101 gtaaaacatt ttatgtttta cctaatgatg acactctacg tgttgaggct tttgagtact 5161 accacacaac tgatcctagt tttctgggta ggtacatgtc agcattaaat cacactaaaa 5221 agtggaaata cccacaagtt aatggtttaa cttctattaa atgggcagat aacaactgtt 5281 atcttgccac tgcattgtta acactccaac aaatagagtt gaagtttaat ccacctgctc 5341 tacaagatgc ttattacaga gcaagggctg gtgaagctgc taacttttgt gcacttatct 5401 tagcctactg taataagaca gtaggtgagt taggtgatgt tagagaaaca atgagttact 5461 tgtttcaaca tgccaattta gattcttgca aaagagtctt gaacgtggtg tgtaaaactt 5521 gtggacaaca gcagacaacc cttaagggtg tagaagctgt tatgtacatg ggcacacttt 5581 cttatgaaca atttaagaaa ggtgttcaga taccttgtac gtgtggtaaa caagctacaa 5641 aatatctagt acaacaggag tcaccttttg ttatgatgtc agcaccacct gctcagtatg 5701 aacttaagca tggtacattt acttgtgcta gtgagtacac tggtaattac cagtgtggtc 5761 actataaaca tataacttct aaagaaactt tgtattgcat agacggtgct ttacttacaa 5821 agtcctcaga atacaaaggt cctattacgg atgttttcta caaagaaaac agttacacaa 5881 caaccataaa accagttact tataaattgg atggtgttgt ttgtacagaa attgacccta 5941 agttggacaa ttattataag aaagacaatt cttatttcac agagcaacca attgatcttg 6001 taccaaacca accatatcca aacgcaagct tcgataattt taagtttgta tgtgataata 6061 tcaaatttgc tgatgattta aaccagttaa ctggttataa gaaacctgct tcaagagagc 6121 ttaaagttac atttttccct gacttaaatg gtgatgtggt ggctattgat tataaacact 6181 acacaccctc ttttaagaaa ggagctaaat tgttacataa acctattgtt tggcatgtta 6241 acaatgcaac taataaagcc acgtataaac caaatacctg gtgtatacgt tgtctttgga 6301 gcacaaaacc agttgaaaca tcaaattcgt ttgatgtact gaagtcagag gacgcgcagg 6361 gaatggataa tcttgcctgc gaagatctaa aaccagtctc tgaagaagta gtggaaaatc 6421 ctaccataca gaaagacgtt cttgagtgta atgtgaaaac taccgaagtt gtaggagaca 6481 ttatacttaa accagcaaat aatagtttaa aaattacaga agaggttggc cacacagatc 6541 taatggctgc ttatgtagac aattctagtc ttactattaa gaaacctaat gaattatcta 6601 gagtattagg tttgaaaacc cttgctactc atggtttagc tgctgttaat agtgtccctt 6661 gggatactat agctaattat gctaagcctt ttcttaacaa agttgttagt acaactacta 6721 acatagttac acggtgttta aaccgtgttt gtactaatta tatgccttat ttctttactt 6781 tattgctaca attgtgtact tttactagaa gtacaaattc tagaattaaa gcatctatgc 6841 cgactactat agcaaagaat actgttaaga gtgtcggtaa attttgtcta gaggcttcat 6901 ttaattattt gaagtcacct aatttttcta aactgataaa tattataatt tggtttttac 6961 tattaagtgt ttgcctaggt tctttaatct actcaaccgc tgctttaggt gttttaatgt 7021 ctaatttagg catgccttct tactgtactg gttacagaga aggctatttg aactctacta 7081 atgtcactat tgcaacctac tgtactggtt ctataccttg tagtgtttgt cttagtggtt 7141 tagattcttt agacacctat ccttctttag aaactataca aattaccatt tcatctttta 7201 aatgggattt aactgctttt ggcttagttg cagagtggtt tttggcatat attcttttca 7261 ctaggttttt ctatgtactt ggattggctg caatcatgca attgtttttc agctattttg 7321 cagtacattt tattagtaat tcttggctta tgtggttaat aattaatctt gtacaaatgg 7381 ccccgatttc agctatggtt agaatgtaca tcttctttgc atcattttat tatgtatgga 7441 aaagttatgt gcatgttgta gacggttgta attcatcaac ttgtatgatg tgttacaaac 7501 gtaatagagc aacaagagtc gaatgtacaa ctattgttaa tggtgttaga aggtcctttt 7561 atgtctatgc taatggaggt aaaggctttt gcaaactaca caattggaat tgtgttaatt 7621 gtgatacatt ctgtgctggt agtacattta ttagtgatga agttgcgaga gacttgtcac 7681 tacagtttaa aagaccaata aatcctactg accagtcttc ttacatcgtt gatagtgtta 7741 cagtgaagaa tggttccatc catctttact ttgataaagc tggtcaaaag acttatgaaa 7801 gacattctct ctctcatttt gttaacttag acaacctgag agctaataac actaaaggtt 7861 cattgcctat taatgttata gtttttgatg gtaaatcaaa atgtgaagaa tcatctgcaa 7921 aatcagcgtc tgtttactac agtcagctta tgtgtcaacc tatactgtta ctagatcagg 7981 cattagtgtc tgatgttggt gatagtgcgg aagttgcagt taaaatgttt gatgcttacg 8041 ttaatacgtt ttcatcaact tttaacgtac caatggaaaa actcaaaaca ctagttgcaa 8101 ctgcagaagc tgaacttgca aagaatgtgt ccttagacaa tgtcttatct acttttattt 8161 cagcagctcg gcaagggttt gttgattcag atgtagaaac taaagatgtt gttgaatgtc 8221 ttaaattgtc acatcaatct gacatagaag ttactggcga tagttgtaat aactatatgc 8281 tcacctataa caaagttgaa aacatgacac cccgtgacct tggtgcttgt attgactgta 8341 gtgcgcgtca tattaatgcg caggtagcaa aaagtcacaa cattgctttg atatggaacg 8401 ttaaagattt catgtcattg tctgaacaac tacgaaaaca aatacgtagt gctgctaaaa 8461 agaataactt accttttaag ttgacatgtg caactactag acaagttgtt aatgttgtaa 8521 caacaaagat agcacttaag ggtggtaaaa ttgttaataa ttggttgaag cagttaatta 8581 aagttacact tgtgttcctt tttgttgctg ctattttcta tttaataaca cctgttcatg 8641 tcatgtctaa acatactgac ttttcaagtg aaatcatagg atacaaggct attgatggtg 8701 gtgtcactcg tgacatagca tctacagata cttgttttgc taacaaacat gctgattttg 8761 acacatggtt tagccagcgt ggtggtagtt atactaatga caaagcttgc ccattgattg 8821 ctgcagtcat aacaagagaa gtgggttttg tcgtgcctgg tttgcctggc acgatattac 8881 gcacaactaa tggtgacttt ttgcatttct tacctagagt ttttagtgca gttggtaaca 8941 tctgttacac accatcaaaa cttatagagt acactgactt tgcaacatca gcttgtgttt 9001 tggctgctga atgtacaatt tttaaagatg cttctggtaa gccagtacca tattgttatg 9061 ataccaatgt actagaaggt tctgttgctt atgaaagttt acgccctgac acacgttatg 9121 tgctcatgga tggctctatt attcaatttc ctaacaccta ccttgaaggt tctgttagag 9181 tggtaacaac ttttgattct gagtactgta ggcacggcac ttgtgaaaga tcagaagctg 9241 gtgtttgtgt atctactagt ggtagatggg tacttaacaa tgattattac agatctttac 9301 caggagtttt ctgtggtgta gatgctgtaa atttacttac taatatgttt acaccactaa 9361 ttcaacctat tggtgctttg gacatatcag catctatagt agctggtggt attgtagcta 9421 tcgtagtaac atgccttgcc tactatttta tgaggtttag aagagctttt ggtgaataca 9481 gtcatgtagt tgcctttaat actttactat tccttatgtc attcactgta ctctgtttaa 9541 caccagttta ctcattctta cctggtgttt attctgttat ttacttgtac ttgacatttt 9601 atcttactaa tgatgtttct tttttagcac atattcagtg gatggttatg ttcacacctt 9661 tagtaccttt ctggataaca attgcttata tcatttgtat ttccacaaag catttctatt 9721 ggttctttag taattaccta aagagacgtg tagtctttaa tggtgtttcc tttagtactt 9781 ttgaagaagc tgcgctgtgc acctttttgt taaataaaga aatgtatcta aagttgcgta 9841 gtgatgtgct attacctctt acgcaatata atagatactt agctctttat aataagtaca 9901 agtattttag tggagcaatg gatacaacta gctacagaga agctgcttgt tgtcatctcg 9961 caaaggctct caatgacttc agtaactcag gttctgatgt tctttaccaa ccaccacaaa 10021 cctctatcac ctcagctgtt ttgcagagtg gttttagaaa aatggcattc ccatctggta 10081 aagttgaggg ttgtatggta caagtaactt gtggtacaac tacacttaac ggtctttggc 10141 ttgatgacgt agtttactgt ccaagacatg tgatctgcac ctctgaagac atgcttaacc 10201 ctaattatga agatttactc attcgtaagt ctaatcataa tttcttggta caggctggta 10261 atgttcaact cagggttatt ggacattcta tgcaaaattg tgtacttaag cttaaggttg 10321 atacagccaa tcctaagaca cctaagtata agtttgttcg cattcaacca ggacagactt 10381 tttcagtgtt agcttgttac aatggttcac catctggtgt ttaccaatgt gctatgaggc 10441 ccaatttcac tattaagggt tcattcctta atggttcatg tggtagtgtt ggttttaaca 10501 tagattatga ctgtgtctct ttttgttaca tgcaccatat ggaattacca actggagttc 10561 atgctggcac agacttagaa ggtaactttt atggaccttt tgttgacagg caaacagcac 10621 aagcagctgg tacggacaca actattacag ttaatgtttt agcttggttg tacgctgctg 10681 ttataaatgg agacaggtgg tttctcaatc gatttaccac aactcttaat gactttaacc 10741 ttgtggctat gaagtacaat tatgaacctc taacacaaga ccatgttgac atactaggac 10801 ctctttctgc tcaaactgga attgccgttt tagatatgtg tgcttcatta aaagaattac 10861 tgcaaaatgg tatgaatgga cgtaccatat tgggtagtgc tttattagaa gatgaattta 10921 caccttttga tgttgttaga caatgctcag gtgttacttt ccaaagtgca gtgaaaagaa 10981 caatcaaggg tacacaccac tggttgttac tcacaatttt gacttcactt ttagttttag 11041 tccagagtac tcaatggtct ttgttctttt ttttgtatga aaatgccttt ttaccttttg 11101 ctatgggtat tattgctatg tctgcttttg caatgatgtt tgtcaaacat aagcatgcat 11161 ttctctgttt gtttttgtta ccttctcttg ccactgtagc ttattttaat atggtctata 11221 tgcctgctag ttgggtgatg cgtattatga catggttgga tatggttgat actagtttgt 11281 ctggttttaa gctaaaagac tgtgttatgt atgcatcagc tgtagtgtta ctaatcctta 11341 tgacagcaag aactgtgtat gatgatggtg ctaggagagt gtggacactt atgaatgtct 11401 tgacactcgt ttataaagtt tattatggta atgctttaga tcaagccatt tccatgtggg 11461 ctcttataat ctctgttact tctaactact caggtgtagt tacaactgtc atgtttttgg 11521 ccagaggtat tgtttttatg tgtgttgagt attgccctat tttcttcata actggtaata 11581 cacttcagtg tataatgcta gtttattgtt tcttaggcta tttttgtact tgttactttg 11641 gcctcttttg tttactcaac cgctacttta gactgactct tggtgtttat gattacttag 11701 tttctacaca ggagtttaga tatatgaatt cacagggact actcccaccc aagaatagca 11761 tagatgcctt caaactcaac attaaattgt tgggtgttgg tggcaaacct tgtatcaaag 11821 tagccactgt acagtctaaa atgtcagatg taaagtgcac atcagtagtc ttactctcag 11881 ttttgcaaca actcagagta gaatcatcat ctaaattgtg ggctcaatgt gtccagttac 11941 acaatgacat tctcttagct aaagatacta ctgaagcctt tgaaaaaatg gtttcactac 12001 tttctgtttt gctttccatg cagggtgctg tagacataaa caagctttgt gaagaaatgc 12061 tggacaacag ggcaacctta caagctatag cctcagagtt tagttccctt ccatcatatg 12121 cagcttttgc tactgctcaa gaagcttatg agcaggctgt tgctaatggt gattctgaag 12181 ttgttcttaa aaagttgaag aagtctttga atgtggctaa atctgaattt gaccgtgatg 12241 cagccatgca acgtaagttg gaaaagatgg ctgatcaagc tatgacccaa atgtataaac 12301 aggctagatc tgaggacaag agggcaaaag ttactagtgc tatgcagaca atgcttttca 12361 ctatgcttag aaagttggat aatgatgcac tcaacaacat tatcaacaat gcaagagatg 12421 gttgtgttcc cttgaacata atacctctta caacagcagc caaactaatg gttgtcatac 12481 cagactataa cacatataaa aatacgtgtg atggtacaac atttacttat gcatcagcat 12541 tgtgggaaat ccaacaggtt gtagatgcag atagtaaaat tgttcaactt agtgaaatta 12601 gtatggacaa ttcacctaat ttagcatggc ctcttattgt aacagcttta agggccaatt 12661 ctgctgtcaa attacagaat aatgagctta gtcctgttgc actacgacag atgtcttgtg 12721 ctgccggtac tacacaaact gcttgcactg atgacaatgc gttagcttac tacaacacaa 12781 caaagggagg taggtttgta cttgcactgt tatccgattt acaggatttg aaatgggcta 12841 gattccctaa gagtgatgga actggtacta tctatacaga actggaacca ccttgtaggt 12901 ttgttacaga cacacctaaa ggtcctaaag tgaagtattt atactttatt aaaggattaa 12961 acaacctaaa tagaggtatg gtacttggta gtttagctgc cacagtacgt ctacaagctg 13021 gtaatgcaac agaagtgcct gccaattcaa ctgtattatc tttctgtgct tttgctgtag 13081 atgctgctaa agcttacaaa gattatctag ctagtggggg acaaccaatc actaattgtg 13141 ttaagatgtt gtgtacacac actggtactg gtcaggcaat aacagttaca ccggaagcca 13201 atatggatca agaatccttt ggtggtgcat cgtgttgtct gtactgccgt tgccacatag 13261 atcatccaaa tcctaaagga ttttgtgact taaaaggtaa gtatgtacaa atacctacaa 13321 cttgtgctaa tgaccctgtg ggttttacac ttaaaaacac agtctgtacc gtctgcggta 13381 tgtggaaagg ttatggctgt agttgtgatc aactccgcga acccatgctt cagtcagctg 13441 atgcacaatc gtttttaaac gggtttgcgg tgtaagtgca gcccgtctta caccgtgcgg 13501 cacaggcact agtactgatg tcgtatacag ggcttttgac atctacaatg ataaagtagc 13561 tggttttgct aaattcctaa aaactaattg ttgtcgcttc caagaaaagg acgaagatga 13621 caatttaatt gattcttact ttgtagttaa gagacacact ttctctaact accaacatga 13681 agaaacaatt tataatttac ttaaggattg tccagctgtt gctaaacatg acttctttaa 13741 gtttagaata gacggtgaca tggtaccaca tatatcacgt caacgtctta ctaaatacac 13801 aatggcagac ctcgtctatg ctttaaggca ttttgatgaa ggtaattgtg acacattaaa 13861 agaaatactt gtcacataca attgttgtga tgatgattat ttcaataaaa aggactggta 13921 tgattttgta gaaaacccag atatattacg cgtatacgcc aacttaggtg aacgtgtacg 13981 ccaagctttg ttaaaaacag tacaattctg tgatgccatg cgaaatgctg gtattgttgg 14041 tgtactgaca ttagataatc aagatctcaa tggtaactgg tatgatttcg gtgatttcat 14101 acaaaccacg ccaggtagtg gagttcctgt tgtagattct tattattcat tgttaatgcc 14161 tatattaacc ttgaccaggg ctttaactgc agagtcacat gttgacactg acttaacaaa 14221 gccttacatt aagtgggatt tgttaaaata tgacttcacg gaagagaggt taaaactctt 14281 tgaccgttat tttaaatatt gggatcagac ataccaccca aattgtgtta actgtttgga 14341 tgacagatgc attctgcatt gtgcaaactt taatgtttta ttctctacag tgttcccact 14401 tacaagtttt ggaccactag tgagaaaaat atttgttgat ggtgttccat ttgtagtttc 14461 aactggatac cacttcagag agctaggtgt tgtacataat caggatgtaa acttacatag 14521 ctctagactt agttttaagg aattacttgt gtatgctgct gaccctgcta tgcacgctgc 14581 ttctggtaat ctattactag ataaacgcac tacgtgcttt tcagtagctg cacttactaa 14641 caatgttgct tttcaaactg tcaaacccgg taattttaac aaagacttct atgactttgc 14701 tgtgtctaag ggtttcttta aggaaggaag ttctgttgaa ttaaaacact tcttctttgc 14761 tcaggatggt aatgctgcta tcagcgatta tgactactat cgttataatc taccaacaat 14821 gtgtgatatc agacaactac tatttgtagt tgaagttgtt gataagtact ttgattgtta 14881 cgatggtggc tgtattaatg ctaaccaagt catcgtcaac aacctagaca aatcagctgg 14941 ttttccattt aataaatggg gtaaggctag actttattat gattcaatga gttatgagga 15001 tcaagatgca cttttcgcat atacaaaacg taatgtcatc cctactataa ctcaaatgaa 15061 tcttaagtat gccattagtg caaagaatag agctcgcacc gtagctggtg tctctatctg 15121 tagtactatg accaatagac agtttcatca aaaattattg aaatcaatag ccgccactag 15181 aggagctact gtagtaattg gaacaagcaa attctatggt ggttggcaca acatgttaaa 15241 aactgtttat agtgatgtag aaaaccctca ccttatgggt tgggattatc ctaaatgtga 15301 tagagccatg cctaatatgc ttagaattat ggcctcactt gttcttgctc gcaaacatac 15361 aacgtgttgt agcttgtcac accgtttcta tagattagct aatgagtgtg ctcaagtatt 15421 gagtgaaatg gtcatgtgtg gcggttcact atatgttaaa ccaggtggaa cctcatcagg 15481 agatgccaca actgcttatg ctaatagtgt ttttaacatt tgtcaagctg tcacggccaa 15541 tgttaatgca cttttatcta ctgatggtaa caaaattgcc gataagtatg tccgcaattt 15601 acaacacaga ctttatgagt gtctctatag aaatagagat gttgacacag actttgtgaa 15661 tgagttttac gcatatttgc gtaaacattt ctcaatgatg atactctctg acgatgctgt 15721 tgtgtgtttc aatagcactt atgcatctca aggtctagtg gctagcataa agaactttaa 15781 gtcagttctt tattatcaaa acaatgtttt tatgtctgaa gcaaaatgtt ggactgagac 15841 tgaccttact aaaggacctc atgaattttg ctctcaacat acaatgctag ttaaacaggg 15901 tgatgattat gtgtaccttc cttacccaga tccatcaaga atcctagggg ccggctgttt 15961 tgtagatgat atcgtaaaaa cagatggtac acttatgatt gaacggttcg tgtctttagc 16021 tatagatgct tacccactta ctaaacatcc taatcaggag tatgctgatg tctttcattt 16081 gtacttacaa tacataagaa agctacatga tgagttaaca ggacacatgt tagacatgta 16141 ttctgttatg cttactaatg ataacacttc aaggtattgg gaacctgagt tttatgaggc 16201 tatgtacaca ccgcatacag tcttacaggc tgttggggct tgtgttcttt gcaattcaca 16261 gacttcatta agatgtggtg cttgcatacg tagaccattc ttatgttgta aatgctgtta 16321 cgaccatgtc atatcaacat cacataaatt agtcttgtct gttaatccgt atgtttgcaa 16381 tgctccaggt tgtgatgtca cagatgtgac tcaactttac ttaggaggta tgagctatta 16441 ttgtaaatca cataaaccac ccattagttt tccattgtgt gctaatggac aagtttttgg 16501 tttatataaa aatacatgtg ttggtagcga taatgttact gactttaatg caattgcaac 16561 atgtgactgg acaaatgctg gtgattacat tttagctaac acctgtactg aaagactcaa 16621 gctttttgca gcagaaacgc tcaaagctac tgaggagaca tttaaactgt cttatggtat 16681 tgctactgta cgtgaagtgc tgtctgacag agaattacat ctttcatggg aagttggtaa 16741 acctagacca ccacttaacc gaaattatgt ctttactggt tatcgtgtaa ctaaaaacag 16801 taaagtacaa ataggagagt acacctttga aaaaggtgac tatggtgatg ctgttgttta 16861 ccgaggtaca acaacttaca aattaaatgt tggtgattat tttgtgctga catcacatac 16921 agtaatgcca ttaagtgcac ctacactagt gccacaagag cactatgtta gaattactgg 16981 cttataccca acactcaata tctcagatga gttttctagc aatgttgcaa attatcaaaa 17041 ggttggtatg caaaagtatt ctacactcca gggaccacct ggtactggta agagtcattt 17101 tgctattggc ctagctctct actacccttc tgctcgcata gtgtatacag cttgctctca 17161 tgccgctgtt gatgcactat gtgagaaggc attaaaatat ttgcctatag ataaatgtag 17221 tagaattata cctgcacgtg ctcgtgtaga gtgttttgat aaattcaaag tgaattcaac 17281 attagaacag tatgtctttt gtactgtaaa tgcattgcct gagacgacag cagatatagt 17341 tgtctttgat gaaatttcaa tggccacaaa ttatgatttg agtgttgtca atgccagatt 17401 acgtgctaag cactatgtgt acattggcga ccctgctcaa ttacctgcac cacgcacatt 17461 gctaactaag ggcacactag aaccagaata tttcaattca gtgtgtagac ttatgaaaac 17521 tataggtcca gacatgttcc tcggaacttg tcggcgttgt cctgctgaaa ttgttgacac 17581 tgtgagtgct ttggtttatg ataataagct taaagcacat aaagacaaat cagctcaatg 17641 ctttaaaatg ttttataagg gtgttatcac gcatgatgtt tcatctgcaa ttaacaggcc 17701 acaaataggc gtggtaagag aattccttac acgtaaccct gcttggagaa aagctgtctt 17761 tatttcacct tataattcac agaatgctgt agcctcaaag attttgggac taccaactca 17821 aactgttgat tcatcacagg gctcagaata tgactatgtc atattcactc aaaccactga 17881 aacagctcac tcttgtaatg taaacagatt taatgttgct attaccagag caaaagtagg 17941 catactttgc ataatgtctg atagagacct ttatgacaag ttgcaattta caagtcttga 18001 aattccacgt aggaatgtgg caactttaca agctgaaaat gtaacaggac tctttaaaga 18061 ttgtagtaag gtaatcactg ggttacatcc tacacaggca cctacacacc tcagtgttga 18121 cactaaattc aaaactgaag gtttatgtgt tgacatacct ggcataccta aggacatgac 18181 ctatagaaga ctcatctcta tgatgggttt taaaatgaat tatcaagtta atggttaccc 18241 taacatgttt atcacccgcg aagaagctat aagacatgta cgtgcatgga ttggcttcga 18301 tgtcgagggg tgtcatgcta ctagagaagc tgttggtacc aatttacctt tacagctagg 18361 tttttctaca ggtgttaacc tagttgctgt acctacaggt tatgttgata cacctaataa 18421 tacagatttt tccagagtta gtgctaaacc accgcctgga gatcaattta aacacctcat 18481 accacttatg tacaaaggac ttccttggaa tgtagtgcgt ataaagattg tacaaatgtt 18541 aagtgacaca cttaaaaatc tctctgacag agtcgtattt gtcttatggg cacatggctt 18601 tgagttgaca tctatgaagt attttgtgaa aataggacct gagcgcacct gttgtctatg 18661 tgatagacgt gccacatgct tttccactgc ttcagacact tatgcctgtt ggcatcattc 18721 tattggattt gattacgtct ataatccgtt tatgattgat gttcaacaat ggggttttac 18781 aggtaaccta caaagcaacc atgatctgta ttgtcaagtc catggtaatg cacatgtagc 18841 tagttgtgat gcaatcatga ctaggtgtct agctgtccac gagtgctttg ttaagcgtgt 18901 tgactggact attgaatatc ctataattgg tgatgaactg aagattaatg cggcttgtag 18961 aaaggttcaa cacatggttg ttaaagctgc attattagca gacaaattcc cagttcttca 19021 cgacattggt aaccctaaag ctattaagtg tgtacctcaa gctgatgtag aatggaagtt 19081 ctatgatgca cagccttgta gtgacaaagc ttataaaata gaagaattat tctattctta 19141 tgccacacat tctgacaaat tcacagatgg tgtatgccta ttttggaatt gcaatgtcga 19201 tagatatcct gctaattcca ttgtttgtag atttgacact agagtgctat ctaaccttaa 19261 cttgcctggt tgtgatggtg gcagtttgta tgtaaataaa catgcattcc acacaccagc 19321 ttttgataaa agtgcttttg ttaatttaaa acaattacca tttttctatt actctgacag 19381 tccatgtgag tctcatggaa aacaagtagt gtcagatata gattatgtac cactaaagtc 19441 tgctacgtgt ataacacgtt gcaatttagg tggtgctgtc tgtagacatc atgctaatga 19501 gtacagattg tatctcgatg cttataacat gatgatctca gctggcttta gcttgtgggt 19561 ttacaaacaa tttgatactt ataacctctg gaacactttt acaagacttc agagtttaga 19621 aaatgtggct tttaatgttg taaataaggg acactttgat ggacaacagg gtgaagtacc 19681 agtttctatc attaataaca ctgtttacac aaaagttgat ggtgttgatg tagaattgtt 19741 tgaaaataaa acaacattac ctgttaatgt agcatttgag ctttgggcta agcgcaacat 19801 taaaccagta ccagaggtga aaatactcaa taatttgggt gtggacattg ctgctaatac 19861 tgtgatctgg gactacaaaa gagatgctcc agcacatata tctactattg gtgtttgttc 19921 tatgactgac atagccaaga aaccaactga aacgatttgt gcaccactca ctgtcttttt 19981 tgatggtaga gttgatggtc aagtagactt atttagaaat gcccgtaatg gtgttcttat 20041 tacagaaggt agtgttaaag gtttacaacc atctgtaggt cccaaacaag ctagtcttaa 20101 tggagtcaca ttaattggag aagccgtaaa aacacagttc aattattata agaaagttga 20161 tggtgttgtc caacaattac ctgaaactta ctttactcag agtagaaatt tacaagaatt 20221 taaacccagg agtcaaatgg aaattgattt cttagaatta gctatggatg aattcattga 20281 acggtataaa ttagaaggct atgccttcga acatatcgtt tatggagatt ttagtcatag 20341 tcagttaggt ggtttacatc tactgattgg actagctaaa cgttttaagg aatcaccttt 20401 tgaattagaa gattttattc ctatggacag tacagttaaa aactatttca taacagatgc 20461 gcaaacaggt tcatctaagt gtgtgtgttc tgttattgat ttattacttg atgattttgt 20521 tgaaataata aaatcccaag atttatctgt agtttctaag gttgtcaaag tgactattga 20581 ctatacagaa atttcattta tgctttggtg taaagatggc catgtagaaa cattttaccc 20641 aaaattacaa tctagtcaag cgtggcaacc gggtgttgct atgcctaatc tttacaaaat 20701 gcaaagaatg ctattagaaa agtgtgacct tcaaaattat ggtgatagtg caacattacc 20761 taaaggcata atgatgaatg tcgcaaaata tactcaactg tgtcaatatt taaacacatt 20821 aacattagct gtaccctata atatgagagt tatacatttt ggtgctggtt ctgataaagg 20881 agttgcacca ggtacagctg ttttaagaca gtggttgcct acgggtacgc tgcttgtcga 20941 ttcagatctt aatgactttg tctctgatgc agattcaact ttgattggtg attgtgcaac 21001 tgtacataca gctaataaat gggatctcat tattagtgat atgtacgacc ctaagactaa 21061 aaatgttaca aaagaaaatg actctaaaga gggttttttc acttacattt gtgggtttat 21121 acaacaaagg ctagctcttg gaggttccgt ggctataaag ataacagaac attcttggaa 21181 tgctgatctt tataagctca tgggacactt cgcatggtgg acagcctttg ttactaatgt 21241 gaatgcgtca tcatctgaag catttttaat tggatgtaat tatcttggca aaccacgcga 21301 acaaatagat ggttatgtca tgcatgcaaa ttacatattt tggaggaata caaatccaat 21361 tcagttgtct tcctattctt tatttgacat gagtaaattt ccccttaaat taaggggtac 21421 tgctgttatg tctttaaaag aaggtcaaat caatgatatg attttatctc ttcttagtaa 21481 aggtagactt ataattagag aaaacaacag agttgttatt tctagtgatg ttcttgttaa 21541 caactaaacg aacaatgttt gtttttcttg ttttattgcc actagtctct agtcagtgtg 21601 ttaatcttac aaccagaact caattacccc ctgcatacac taattctttc acacgtggtg 21661 tttattaccc tgacaaagtt ttcagatcct cagttttaca ttcaactcag gacttgttct 21721 tacctttctt ttccaatgtt acttggttcc atgctataca tgtctctggg accaatggta 21781 ctaagaggtt tgataaccct gtcctaccat ttaatgatgg tgtttatttt gcttccactg 21841 agaagtctaa cataataaga ggctggattt ttggtactac tttagattcg aagacccagt 21901 ccctacttat tgttaataac gctactaatg ttgttattaa agtctgtgaa tttcaatttt 21961 gtaatgatcc atttttgggt gtttattacc acaaaaacaa caaaagttgg atggaaagtg 22021 agttcagagt ttattctagt gcgaataatt gcacttttga atatgtctct cagccttttc 22081 ttatggacct tgaaggaaaa cagggtaatt tcaaaaatct tagggaattt gtgtttaaga 22141 atattgatgg ttattttaaa atatattcta agcacacgcc tattaattta gtgcgtgatc 22201 tccctcaggg tttttcggct ttagaaccat tggtagattt gccaataggt attaacatca 22261 ctaggtttca aactttactt gctttacata gaagttattt gactcctggt gattcttctt 22321 caggttggac agctggtgct gcagcttatt atgtgggtta tcttcaacct aggacttttc 22381 tattaaaata taatgaaaat ggaaccatta cagatgctgt agactgtgca cttgaccctc 22441 tctcagaaac aaagtgtacg ttgaaatcct tcactgtaga aaaaggaatc tatcaaactt 22501 ctaactttag agtccaacca acagaatcta ttgttagatt tcctaatatt acaaacttgt 22561 gcccttttgg tgaagttttt aacgccacca gatttgcatc tgtttatgct tggaacagga 22621 agagaatcag caactgtgtt gctgattatt ctgtcctata taattccgca tcattttcca 22681 cttttaagtg ttatggagtg tctcctacta aattaaatga tctctgcttt actaatgtct 22741 atgcagattc atttgtaatt agaggtgatg aagtcagaca aatcgctcca gggcaaactg 22801 gaaagattgc tgattataat tataaattac cagatgattt tacaggctgc gttatagctt 22861 ggaattctaa caatcttgat tctaaggttg gtggtaatta taattacctg tatagattgt 22921 ttaggaagtc taatctcaaa ccttttgaga gagatatttc aactgaaatc tatcaggccg 22981 gtagcacacc ttgtaatggt gttgaaggtt ttaattgtta ctttccttta caatcatatg 23041 gtttccaacc cactaatggt gttggttacc aaccatacag agtagtagta ctttcttttg 23101 aacttctaca tgcaccagca actgtttgtg gacctaaaaa gtctactaat ttggttaaaa 23161 acaaatgtgt caatttcaac ttcaatggtt taacaggcac aggtgttctt actgagtcta 23221 acaaaaagtt tctgcctttc caacaatttg gcagagacat tgctgacact actgatgctg 23281 tccgtgatcc acagacactt gagattcttg acattacacc atgttctttt ggtggtgtca 23341 gtgttataac accaggaaca aatacttcta accaggttgc tgttctttat cagggtgtta 23401 actgcacaga agtccctgtt gctattcatg cagatcaact tactcctact tggcgtgttt 23461 attctacagg ttctaatgtt tttcaaacac gtgcaggctg tttaataggg gctgaacatg 23521 tcaacaactc atatgagtgt gacataccca ttggtgcagg tatatgcgct agttatcaga 23581 ctcagactaa ttctcctcgg cgggcacgta gtgtagctag tcaatctatc attgcctaca 23641 ctatgtcact tggtgcagaa aattcagttg cttactctaa taactctatt gccataccca 23701 caaattttac tattagtgtt accacagaaa ttctaccagt gtctatgacc aagacatcag 23761 tagattgtac aatgtacatt tgtggtgatt caactgaatg cagcaatctt ttgttgcaat 23821 atggcagttt ttgtacacaa ttaaaccgtg ctttaactgg aatagctgtt gaacaagaca 23881 aaaacaccca agaagttttt gcacaagtca aacaaattta caaaacacca ccaattaaag 23941 attttggtgg ttttaatttt tcacaaatat taccagatcc atcaaaacca agcaagaggt 24001 catttattga agatctactt ttcaacaaag tgacacttgc agatgctggc ttcatcaaac 24061 aatatggtga ttgccttggt gatattgctg ctagagacct catttgtgca caaaagttta 24121 acggccttac tgttttgcca cctttgctca cagatgaaat gattgctcaa tacacttctg 24181 cactgttagc gggtacaatc acttctggtt ggacctttgg tgcaggtgct gcattacaaa 24241 taccatttgc tatgcaaatg gcttataggt ttaatggtat tggagttaca cagaatgttc 24301 tctatgagaa ccaaaaattg attgccaacc aatttaatag tgctattggc aaaattcaag 24361 actcactttc ttccacagca agtgcacttg gaaaacttca agatgtggtc aaccaaaatg 24421 cacaagcttt aaacacgctt gttaaacaac ttagctccaa ttttggtgca atttcaagtg 24481 ttttaaatga tatcctttca cgtcttgaca aagttgaggc tgaagtgcaa attgataggt 24541 tgatcacagg cagacttcaa agtttgcaga catatgtgac tcaacaatta attagagctg 24601 cagaaatcag agcttctgct aatcttgctg ctactaaaat gtcagagtgt gtacttggac 24661 aatcaaaaag agttgatttt tgtggaaagg gctatcatct tatgtccttc cctcagtcag 24721 cacctcatgg tgtagtcttc ttgcatgtga cttatgtccc tgcacaagaa aagaacttca 24781 caactgctcc tgccatttgt catgatggaa aagcacactt tcctcgtgaa ggtgtctttg 24841 tttcaaatgg cacacactgg tttgtaacac aaaggaattt ttatgaacca caaatcatta 24901 ctacagacaa cacatttgtg tctggtaact gtgatgttgt aataggaatt gtcaacaaca 24961 cagtttatga tcctttgcaa cctgaattag actcattcaa ggaggagtta gataaatatt 25021 ttaagaatca tacatcacca gatgttgatt taggtgacat ctctggcatt aatgcttcag 25081 ttgtaaacat tcaaaaagaa attgaccgcc tcaatgaggt tgccaagaat ttaaatgaat 25141 ctctcatcga tctccaagaa cttggaaagt atgagcagta tataaaatgg ccatggtaca 25201 tttggctagg ttttatagct ggcttgattg ccatagtaat ggtgacaatt atgctttgct 25261 gtatgaccag ttgctgtagt tgtctcaagg gctgttgttc ttgtggatcc tgctgcaaat 25321 ttgatgaaga cgactctgag ccagtgctca aaggagtcaa attacattac acataaacga 25381 acttatggat ttgtttatga gaatcttcac aattggaact gtaactttga agcaaggtga 25441 aatcaaggat gctactcctt cagattttgt tcgcgctact gcaacgatac cgatacaagc 25501 ctcactccct ttcggatggc ttattgttgg cgttgcactt cttgctgttt ttcagagcgc 25561 ttccaaaatc ataaccctca aaaagagatg gcaactagca ctctccaagg gtgttcactt 25621 tgtttgcaac ttgctgttgt tgtttgtaac agtttactca caccttttgc tcgttgctgc 25681 tggccttgaa gccccttttc tctatcttta tgctttagtc tacttcttgc agagtataaa 25741 ctttgtaaga ataataatga ggctttggct ttgctggaaa tgccgttcca aaaacccatt 25801 actttatgat gccaactatt ttctttgctg gcatactaat tgttacgact attgtatacc 25861 ttacaatagt gtaacttctt caattgtcat tacttcaggt gatggcacaa caagtcctat 25921 ttctgaacat gactaccaga ttggtggtta tactgaaaaa tgggaatctg gagtaaaaga 25981 ctgtgttgta ttacacagtt acttcacttc agactattac cagctgtact caactcaatt 26041 gagtacagac actggtgttg aacatgttac cttcttcatc tacaataaaa ttgttgatga 26101 gcctgaagaa catgtccaaa ttcacacaat cgacggttca tccggagttg ttaatccagt 26161 aatggaacca atttatgatg aaccgacgac gactactagc gtgcctttgt aagcacaagc 26221 tgatgagtac gaacttatgt actcattcgt ttcggaagag acaggtacgt taatagttaa 26281 tagcgtactt ctttttcttg ctttcgtggt attcttgcta gttacactag ccatccttac 26341 tgcgcttcga ttgtgtgcgt actgctgcaa tattgttaac gtgagtcttg taaaaccttc 26401 tttttacgtt tactctcgtg ttaaaaatct gaattcttct agagttcctg atcttctggt 26461 ctaaacgaac taaatattat attagttttt ctgtttggaa ctttaatttt agccatggca 26521 gattccaacg gtactattac cgttgaagag cttaaaaagc tccttgaaca atggaaccta 26581 gtaataggtt tcctattcct tacatggatt tgtcttctac aatttgccta tgccaacagg 26641 aataggtttt tgtatataat taagttaatt ttcctctggc tgttatggcc agtaacttta 26701 gcttgttttg tgcttgctgc tgtttacaga ataaattgga tcaccggtgg aattgctatc 26761 gcaatggctt gtcttgtagg cttgatgtgg ctcagctact tcattgcttc tttcagactg 26821 tttgcgcgta cgcgttccat gtggtcattc aatccagaaa ctaacattct tctcaacgtg 26881 ccactccatg gcactattct gaccagaccg cttctagaaa gtgaactcgt aatcggagct 26941 gtgatccttc gtggacatct tcgtattgct ggacaccatc taggacgctg tgacatcaag 27001 gacctgccta aagaaatcac tgttgctaca tcacgaacgc tttcttatta caaattggga 27061 gcttcgcagc gtgtagcagg tgactcaggt tttgctgcat acagtcgcta caggattggc 27121 aactataaat taaacacaga ccattccagt agcagtgaca atattgcttt gcttgtacag 27181 taagtgacaa cagatgtttc atctcgttga ctttcaggtt actatagcag agatattact 27241 aattattatg aggactttta aagtttccat ttggaatctt gattacatca taaacctcat 27301 aattaaaaat ttatctaagt cactaactga gaataaatat tctcaattag atgaagagca 27361 accaatggag attgattaaa cgaacatgaa aattattctt ttcttggcac tgataacact 27421 cgctacttgt gagctttatc actaccaaga gtgtgttaga ggtacaacag tacttttaaa 27481 agaaccttgc tcttctggaa catacgaggg caattcacca tttcatcctc tagctgataa 27541 caaatttgca ctgacttgct ttagcactca atttgctttt gcttgtcctg acggcgtaaa 27601 acacgtctat cagttacgtg ccagatcagt ttcacctaaa ctgttcatca gacaagagga 27661 agttcaagaa ctttactctc caatttttct tattgttgcg gcaatagtgt ttataacact 27721 ttgcttcaca ctcaaaagaa agacagaatg attgaacttt cattaattga cttctatttg 27781 tgctttttag cctttctgct attccttgtt ttaattatgc ttattatctt ttggttctca 27841 cttgaactgc aagatcataa tgaaacttgt cacgcctaaa cgaacatgaa atttcttgtt 27901 ttcttaggaa tcatcacaac tgtagctgca tttcaccaag aatgtagttt acagtcatgt 27961 actcaacatc aaccatatgt agttgatgac ccgtgtccta ttcacttcta ttctaaatgg 28021 tatattagag taggagctag aaaatcagca cctttaattg aattgtgcgt ggatgaggct 28081 ggttctaaat cacccattca gtacatcgat atcggtaatt atacagtttc ctgtttacct 28141 tttacaatta attgccagga acctaaattg ggtagtcttg tagtgcgttg ttcgttctat 28201 gaagactttt tagagtatca tgacgttcgt gttgttttag atttcatcta aacgaacaaa 28261 ctaaaatgtc tgataatgga ccccaaaatc agcgaaatgc accccgcatt acgtttggtg 28321 gaccctcaga ttcaactggc agtaaccaga atggagaacg cagtggggcg cgatcaaaac 28381 aacgtcggcc ccaaggttta cccaataata ctgcgtcttg gttcaccgct ctcactcaac 28441 atggcaagga agaccttaaa ttccctcgag gacaaggcgt tccaattaac accaatagca 28501 gtccagatga ccaaattggc tactaccgaa gagctaccag acgaattcgt ggtggtgacg 28561 gtaaaatgaa agatctcagt ccaagatggt atttctacta cctaggaact gggccagaag 28621 ctggacttcc ctatggtgct aacaaagacg gcatcatatg ggttgcaact gagggagcct 28681 tgaatacacc aaaagatcac attggcaccc gcaatcctgc taacaatgct gcaatcgtgc 28741 tacaacttcc tcaaggaaca acattgccaa aaggcttcta cgcagaaggg agcagaggcg 28801 gcagtcaagc ctcttctcgt tcctcatcac gtagtcgcaa cagttcaaga aattcaactc 28861 caggcagcag taggggaact tctcctgcta gaatggctgg caatggcggt gatgctgctc 28921 ttgctttgct gctgcttgac agattgaacc agcttgagag caaaatgtct ggtaaaggcc 28981 aacaacaaca aggccaaact gtcactaaga aatctgctgc tgaggcttct aagaagcctc 29041 ggcaaaaacg tactgccact aaagcataca atgtaacaca agctttcggc agacgtggtc 29101 cagaacaaac ccaaggaaat tttggggacc aggaactaat cagacaagga actgattaca 29161 aacattggcc gcaaattgca caatttgccc ccagcgcttc agcgttcttc ggaatgtcgc 29221 gcattggcat ggaagtcaca ccttcgggaa cgtggttgac ctacacaggt gccatcaaat 29281 tggatgacaa agatccaaat ttcaaagatc aagtcatttt gctgaataag catattgacg 29341 catacaaaac attcccacca acagagccta aaaaggacaa aaagaagaag gctgatgaaa 29401 ctcaagcctt accgcagaga cagaagaaac agcaaactgt gactcttctt cctgctgcag 29461 atttggatga tttctccaaa caattgcaac aatccatgag cagtgctgac tcaactcagg 29521 cctaaactca tgcagaccac acaaggcaga tgggctatat aaacgttttc gcttttccgt 29581 ttacgatata tagtctactc ttgtgcagaa tgaattctcg taactacata gcacaagtag 29641 atgtagttaa ctttaatctc acatagcaat ctttaatcag tgtgtaacat tagggaggac 29701 ttgaaagagc caccacattt tcaccgaggc cacgcggagt acgatcgagt gtacagtgaa 29761 caatgctagg gagagctgcc tatatggaag agccctaatg tgtaaaatta attttagtag 29821 tgctatcccc atgtgatttt aatagcttct taggagaatg acaaaaaaaa aaaaaaaaaa 29881 aaaaaaaaaa aaaaa //